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Years of life lost as a measure of cancer burden on a national level.

Brustugun OT, Møller B, Helland A - Br. J. Cancer (2014)

Bottom Line: Lung cancer caused almost as many YLL alone (22.1% of cancer-caused YLL) as colon, prostate and breast cancer combined (23.1%).From 1997 to 2012, cancer-caused YLL as a fraction of all YLL increased from 32.5% to 35.2%, but with major differences among diagnoses.Public health efforts and research funding should be explicitly directed at preventing premature deaths.

View Article: PubMed Central - PubMed

Affiliation: 1] Department of Oncology, Oslo University Hospital-The Norwegian Radium Hospital, Oslo, Norway [2] Institute of Clinical Medicine, University of Oslo, Oslo, Norway.

ABSTRACT

Background: The severity of cancers is often measured in number of deaths. However, number of years of life lost (YLL) may be a more appropriate indicator of impact on society. Here we have calculated the YLL of adult cancers in Norway for the year 2012, as well as for the previous 15-year period.

Methods: Data on age composition, expected remaining years of life, total numbers of deaths and deaths due to cancer were retrieved from the National Census Agency Statistics Norway. YLL were calculated for both sexes aged 25-99 years based on each individual's age at death, and the expected remaining years of life at that age.

Results: Cancer deaths represented 25.8% of all adult deaths in 2012, with a lower fraction of females (28.7% in men and 23.1% in women), whereas cancer represented 35.2% of all YLL, with a higher fraction of females (32.8% in men and 37.8% in women). Females loose on average more life years to cancer than men (14.9 vs 12.7 years). Average YLL varied from 23.7 (cervical cancer) to 7.9 (prostate cancer). Lung cancer caused almost as many YLL alone (22.1% of cancer-caused YLL) as colon, prostate and breast cancer combined (23.1%). From 1997 to 2012, cancer-caused YLL as a fraction of all YLL increased from 32.5% to 35.2%, but with major differences among diagnoses.

Conclusions: Cancer is a major and increasing cause of premature deaths, and YLL may be a more accurate measure than number of deaths. Public health efforts and research funding should be explicitly directed at preventing premature deaths.

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Related in: MedlinePlus

Percentage YLL of total cancer-caused YLL in Norway in 2012 for 18 most frequent cancer types. Percentage YLL of total cancer-caused YLL in Norway 2012 for 18 most frequent cancer types, both sexes combined (A). Average YLL of the 18 most frequent cancer types (B).
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fig2: Percentage YLL of total cancer-caused YLL in Norway in 2012 for 18 most frequent cancer types. Percentage YLL of total cancer-caused YLL in Norway 2012 for 18 most frequent cancer types, both sexes combined (A). Average YLL of the 18 most frequent cancer types (B).

Mentions: Based on the total number of deaths at each age level, multiplied by the expected remaining years of life on each level, a hypothetical total of 421 047 YLL in age 25–99 years was lost in 2012. In total, 148 095 (35.2%) of these were due to cancer. The fraction of cancer-caused YLL of total YLL was higher in females than in men (37.8% and 32.8%, respectively). Lung cancer was the main cause (32 691 YLL—22.1% of all cancer-caused YLL)—nearly as many as colon (15 646, 10.6%), breast (10 700, 7.2%) and prostate cancer (7979, 5.4%) combined (34 275, 23.1%). The YLL for all 18 cancers is shown as percentage of all cancer-caused YLL (Figure 2A).


Years of life lost as a measure of cancer burden on a national level.

Brustugun OT, Møller B, Helland A - Br. J. Cancer (2014)

Percentage YLL of total cancer-caused YLL in Norway in 2012 for 18 most frequent cancer types. Percentage YLL of total cancer-caused YLL in Norway 2012 for 18 most frequent cancer types, both sexes combined (A). Average YLL of the 18 most frequent cancer types (B).
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4150272&req=5

fig2: Percentage YLL of total cancer-caused YLL in Norway in 2012 for 18 most frequent cancer types. Percentage YLL of total cancer-caused YLL in Norway 2012 for 18 most frequent cancer types, both sexes combined (A). Average YLL of the 18 most frequent cancer types (B).
Mentions: Based on the total number of deaths at each age level, multiplied by the expected remaining years of life on each level, a hypothetical total of 421 047 YLL in age 25–99 years was lost in 2012. In total, 148 095 (35.2%) of these were due to cancer. The fraction of cancer-caused YLL of total YLL was higher in females than in men (37.8% and 32.8%, respectively). Lung cancer was the main cause (32 691 YLL—22.1% of all cancer-caused YLL)—nearly as many as colon (15 646, 10.6%), breast (10 700, 7.2%) and prostate cancer (7979, 5.4%) combined (34 275, 23.1%). The YLL for all 18 cancers is shown as percentage of all cancer-caused YLL (Figure 2A).

Bottom Line: Lung cancer caused almost as many YLL alone (22.1% of cancer-caused YLL) as colon, prostate and breast cancer combined (23.1%).From 1997 to 2012, cancer-caused YLL as a fraction of all YLL increased from 32.5% to 35.2%, but with major differences among diagnoses.Public health efforts and research funding should be explicitly directed at preventing premature deaths.

View Article: PubMed Central - PubMed

Affiliation: 1] Department of Oncology, Oslo University Hospital-The Norwegian Radium Hospital, Oslo, Norway [2] Institute of Clinical Medicine, University of Oslo, Oslo, Norway.

ABSTRACT

Background: The severity of cancers is often measured in number of deaths. However, number of years of life lost (YLL) may be a more appropriate indicator of impact on society. Here we have calculated the YLL of adult cancers in Norway for the year 2012, as well as for the previous 15-year period.

Methods: Data on age composition, expected remaining years of life, total numbers of deaths and deaths due to cancer were retrieved from the National Census Agency Statistics Norway. YLL were calculated for both sexes aged 25-99 years based on each individual's age at death, and the expected remaining years of life at that age.

Results: Cancer deaths represented 25.8% of all adult deaths in 2012, with a lower fraction of females (28.7% in men and 23.1% in women), whereas cancer represented 35.2% of all YLL, with a higher fraction of females (32.8% in men and 37.8% in women). Females loose on average more life years to cancer than men (14.9 vs 12.7 years). Average YLL varied from 23.7 (cervical cancer) to 7.9 (prostate cancer). Lung cancer caused almost as many YLL alone (22.1% of cancer-caused YLL) as colon, prostate and breast cancer combined (23.1%). From 1997 to 2012, cancer-caused YLL as a fraction of all YLL increased from 32.5% to 35.2%, but with major differences among diagnoses.

Conclusions: Cancer is a major and increasing cause of premature deaths, and YLL may be a more accurate measure than number of deaths. Public health efforts and research funding should be explicitly directed at preventing premature deaths.

Show MeSH
Related in: MedlinePlus