Thigh fat and muscle each contribute to excess cardiometabolic risk in South Asians, independent of visceral adipose tissue.
Bottom Line: Accounting for body size, South Asians had greater VAT and TSAT than Europeans, but less thigh muscle.Insulin resistance did not account for the effects of TSAT or thigh muscle.Effects of TSAT and thigh muscle were independent of insulin resistance.
Affiliation: National Heart and Lung Institute, Imperial College London, London, UK.Show MeSH
Related in: MedlinePlus
Mentions: Taken separately, fat depots were positively associated with cardiometabolic risk factors (Figure 1), with VAT generally showing the strongest associations. Thigh muscle area was negatively associated with all cardiometabolic traits, significantly so in South Asians for diabetes, HbA1c, and clinical and subclinical CHD.
Affiliation: National Heart and Lung Institute, Imperial College London, London, UK.