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Myasthenia gravis-like syndrome presenting as a component of the paraneoplastic syndrome of lung adenocarcinoma in a nonsmoker.

Eivaz-Mohammadi S, Gonzalez-Ibarra F, Hekmatjou H, Mikkilineni R, Patel A, Syed AK - Case Rep Oncol Med (2014)

Bottom Line: It is commonly seen in the periphery of the lungs.Myasthenia gravis is generally associated with mediastinal malignancies and rarely associated with adenocarcinoma of the lung.We present a case of a 38-year-old male nonsmoker with rapidly progressive adenocarcinoma of the lung associated with myasthenia gravis, a patient whom expired within 27 days of hospital admission and diagnosis.

View Article: PubMed Central - PubMed

Affiliation: Department of Internal Medicine, Jersey City Medical Center, Jersey City, NJ 07302, USA.

ABSTRACT
Adenocarcinoma of the lung is the most common form of lung cancer in nonsmokers. It is commonly seen in the periphery of the lungs. Myasthenia gravis is generally associated with mediastinal malignancies and rarely associated with adenocarcinoma of the lung. We present a case of a 38-year-old male nonsmoker with rapidly progressive adenocarcinoma of the lung associated with myasthenia gravis, a patient whom expired within 27 days of hospital admission and diagnosis.

No MeSH data available.


Related in: MedlinePlus

Chest X-ray showing a large right hilar mass extending to the right upper lobe with associated fine loss in the right lung. There is a right pleural effusion seen as well.
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fig1: Chest X-ray showing a large right hilar mass extending to the right upper lobe with associated fine loss in the right lung. There is a right pleural effusion seen as well.

Mentions: CT chest was ordered and revealed a large right mediastinal mass measuring 8.8 × 6.2 × 9.6 cm (Figures 1 and 2), consistent with malignancy, involving the right cardiac atrium with occlusion of the right main pulmonary artery either invaded or compressed by the mass, and no significant opacification of the right pulmonary arteries. The mass was further found to compress the superior vena cava with mild deviation to the left, also extending to the perihilar right upper lobe. A small right-sided pleural effusion was seen as well as a pericardial effusion measuring 1 cm anteriorly. A 1.2 × 0.5 cm pleural based nodule was found in the posterior left lower lobe. The patient was subsequently admitted to the hospital for further evaluation and a request for documentation of previous testing, including the “neurologic testing,” was placed (Figure 3).


Myasthenia gravis-like syndrome presenting as a component of the paraneoplastic syndrome of lung adenocarcinoma in a nonsmoker.

Eivaz-Mohammadi S, Gonzalez-Ibarra F, Hekmatjou H, Mikkilineni R, Patel A, Syed AK - Case Rep Oncol Med (2014)

Chest X-ray showing a large right hilar mass extending to the right upper lobe with associated fine loss in the right lung. There is a right pleural effusion seen as well.
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4129963&req=5

fig1: Chest X-ray showing a large right hilar mass extending to the right upper lobe with associated fine loss in the right lung. There is a right pleural effusion seen as well.
Mentions: CT chest was ordered and revealed a large right mediastinal mass measuring 8.8 × 6.2 × 9.6 cm (Figures 1 and 2), consistent with malignancy, involving the right cardiac atrium with occlusion of the right main pulmonary artery either invaded or compressed by the mass, and no significant opacification of the right pulmonary arteries. The mass was further found to compress the superior vena cava with mild deviation to the left, also extending to the perihilar right upper lobe. A small right-sided pleural effusion was seen as well as a pericardial effusion measuring 1 cm anteriorly. A 1.2 × 0.5 cm pleural based nodule was found in the posterior left lower lobe. The patient was subsequently admitted to the hospital for further evaluation and a request for documentation of previous testing, including the “neurologic testing,” was placed (Figure 3).

Bottom Line: It is commonly seen in the periphery of the lungs.Myasthenia gravis is generally associated with mediastinal malignancies and rarely associated with adenocarcinoma of the lung.We present a case of a 38-year-old male nonsmoker with rapidly progressive adenocarcinoma of the lung associated with myasthenia gravis, a patient whom expired within 27 days of hospital admission and diagnosis.

View Article: PubMed Central - PubMed

Affiliation: Department of Internal Medicine, Jersey City Medical Center, Jersey City, NJ 07302, USA.

ABSTRACT
Adenocarcinoma of the lung is the most common form of lung cancer in nonsmokers. It is commonly seen in the periphery of the lungs. Myasthenia gravis is generally associated with mediastinal malignancies and rarely associated with adenocarcinoma of the lung. We present a case of a 38-year-old male nonsmoker with rapidly progressive adenocarcinoma of the lung associated with myasthenia gravis, a patient whom expired within 27 days of hospital admission and diagnosis.

No MeSH data available.


Related in: MedlinePlus