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Laryngeal lymphoma: the high and low grades of rare lymphoma involvement sites.

Azzopardi CP, Degaetano J, Betts A, Farrugia E, Magri C, Refalo N, Gatt A, Camilleri DJ - Case Rep Med (2014)

Bottom Line: The larynx is an extremely rare site of involvement by lymphomatous disease.We present two cases of isolated laryngeal high-grade and another low-grade lymphoma, together with a literature review of laryngeal lymphoma management.

View Article: PubMed Central - PubMed

Affiliation: Department of Haemato-Oncology, Mater Dei Hospital, Tal-Qroqq, Msida MSD 2090, Malta.

ABSTRACT
The larynx is an extremely rare site of involvement by lymphomatous disease. We present two cases of isolated laryngeal high-grade and another low-grade lymphoma, together with a literature review of laryngeal lymphoma management.

No MeSH data available.


Related in: MedlinePlus

Computed tomography at presentation.
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fig1: Computed tomography at presentation.

Mentions: An 82-year-old Caucasian lady known to suffer from ischaemic heart disease, hypertension, and mild renal impairment was admitted to hospital in November 2010 complaining of a 3-month history of increasing facial pain and difficulty breathing. She had previously undergone surgery for a complicated diverticular abscess two years prior to this presentation and this had resulted in a defunctioning colostomy. Physical examination showed no lymphadenopathy or organomegaly. Indirect laryngoscopy showed a mass at the base of the tongue, involving the epiglottis and causing airway obstruction. The patient underwent an emergency tracheostomy to secure the airway. Investigations showed a white blood count of 11.3 × 109/L, haemoglobin of 104 g/L, platelets of 296 × 109/L, and a normal serum lactate dehydrogenase level of 209 U/L. Staging with computed tomography only confirmed disease in the laryngeal area (Figure 1) and did not show any thoracic, abdominal, or pelvic lymphadenopathy. Bone marrow aspiration and biopsy showed no evidence of bone marrow involvement.


Laryngeal lymphoma: the high and low grades of rare lymphoma involvement sites.

Azzopardi CP, Degaetano J, Betts A, Farrugia E, Magri C, Refalo N, Gatt A, Camilleri DJ - Case Rep Med (2014)

Computed tomography at presentation.
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4129931&req=5

fig1: Computed tomography at presentation.
Mentions: An 82-year-old Caucasian lady known to suffer from ischaemic heart disease, hypertension, and mild renal impairment was admitted to hospital in November 2010 complaining of a 3-month history of increasing facial pain and difficulty breathing. She had previously undergone surgery for a complicated diverticular abscess two years prior to this presentation and this had resulted in a defunctioning colostomy. Physical examination showed no lymphadenopathy or organomegaly. Indirect laryngoscopy showed a mass at the base of the tongue, involving the epiglottis and causing airway obstruction. The patient underwent an emergency tracheostomy to secure the airway. Investigations showed a white blood count of 11.3 × 109/L, haemoglobin of 104 g/L, platelets of 296 × 109/L, and a normal serum lactate dehydrogenase level of 209 U/L. Staging with computed tomography only confirmed disease in the laryngeal area (Figure 1) and did not show any thoracic, abdominal, or pelvic lymphadenopathy. Bone marrow aspiration and biopsy showed no evidence of bone marrow involvement.

Bottom Line: The larynx is an extremely rare site of involvement by lymphomatous disease.We present two cases of isolated laryngeal high-grade and another low-grade lymphoma, together with a literature review of laryngeal lymphoma management.

View Article: PubMed Central - PubMed

Affiliation: Department of Haemato-Oncology, Mater Dei Hospital, Tal-Qroqq, Msida MSD 2090, Malta.

ABSTRACT
The larynx is an extremely rare site of involvement by lymphomatous disease. We present two cases of isolated laryngeal high-grade and another low-grade lymphoma, together with a literature review of laryngeal lymphoma management.

No MeSH data available.


Related in: MedlinePlus