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An unusual cause of recurrent pneumonia in adults.

Dhir V, Sagar V, Aggarwal A, Rawat A, Singhal M - Lung India (2014)

Bottom Line: It presents with recurrent infections and has been described as first presenting in adulthood with recurrent respiratory tract infections.Unlike its better known counterpart of IgA deficiency, this particular immunodeficiency is often overlooked.We present a case of selective IgM deficiency who presented with recurrent respiratory infections.

View Article: PubMed Central - PubMed

Affiliation: Department of Internal Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

ABSTRACT
Selective IgM deficiency is a rare primary immunodeficiency defined as isolated low levels of IgM. It presents with recurrent infections and has been described as first presenting in adulthood with recurrent respiratory tract infections. Unlike its better known counterpart of IgA deficiency, this particular immunodeficiency is often overlooked. We present a case of selective IgM deficiency who presented with recurrent respiratory infections.

No MeSH data available.


Related in: MedlinePlus

(a) Contrast enhanced computed tomography chest axial image in lung window setting show areas of consolidations in inferior segment of lingular lobe and lateral and posterior basal segments of left lower lobe (b) Axial image in mediastinal window demonstrate left pleural effusion
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Figure 1: (a) Contrast enhanced computed tomography chest axial image in lung window setting show areas of consolidations in inferior segment of lingular lobe and lateral and posterior basal segments of left lower lobe (b) Axial image in mediastinal window demonstrate left pleural effusion

Mentions: A 58-year old Indian male presented in June 2012 with a 4-day history of high grade fever and mucopurulent expectoration. On examination, patient was febrile (101°F) with arterial oxygen saturation of 93% and crepitations in left infra-axillary and infra-scapular region on respiratory examination. Chest radiograph and computed tomography of the thorax revealed consolidation in lingula and left lower lobe and left sided pleural effusion. [Figure 1] Pleural fluid was exudative with sterile cultures for bacteria and mycobacteria. White blood count was elevated (21000/μl); however, blood and urine culture were sterile. Patient was empirically started on broad-spectrum intravenous (IV) antibiotics (piperacillin-tazobactam 4.5 g four times a day) with which the patient slowly improved over 10 days.


An unusual cause of recurrent pneumonia in adults.

Dhir V, Sagar V, Aggarwal A, Rawat A, Singhal M - Lung India (2014)

(a) Contrast enhanced computed tomography chest axial image in lung window setting show areas of consolidations in inferior segment of lingular lobe and lateral and posterior basal segments of left lower lobe (b) Axial image in mediastinal window demonstrate left pleural effusion
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4129610&req=5

Figure 1: (a) Contrast enhanced computed tomography chest axial image in lung window setting show areas of consolidations in inferior segment of lingular lobe and lateral and posterior basal segments of left lower lobe (b) Axial image in mediastinal window demonstrate left pleural effusion
Mentions: A 58-year old Indian male presented in June 2012 with a 4-day history of high grade fever and mucopurulent expectoration. On examination, patient was febrile (101°F) with arterial oxygen saturation of 93% and crepitations in left infra-axillary and infra-scapular region on respiratory examination. Chest radiograph and computed tomography of the thorax revealed consolidation in lingula and left lower lobe and left sided pleural effusion. [Figure 1] Pleural fluid was exudative with sterile cultures for bacteria and mycobacteria. White blood count was elevated (21000/μl); however, blood and urine culture were sterile. Patient was empirically started on broad-spectrum intravenous (IV) antibiotics (piperacillin-tazobactam 4.5 g four times a day) with which the patient slowly improved over 10 days.

Bottom Line: It presents with recurrent infections and has been described as first presenting in adulthood with recurrent respiratory tract infections.Unlike its better known counterpart of IgA deficiency, this particular immunodeficiency is often overlooked.We present a case of selective IgM deficiency who presented with recurrent respiratory infections.

View Article: PubMed Central - PubMed

Affiliation: Department of Internal Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

ABSTRACT
Selective IgM deficiency is a rare primary immunodeficiency defined as isolated low levels of IgM. It presents with recurrent infections and has been described as first presenting in adulthood with recurrent respiratory tract infections. Unlike its better known counterpart of IgA deficiency, this particular immunodeficiency is often overlooked. We present a case of selective IgM deficiency who presented with recurrent respiratory infections.

No MeSH data available.


Related in: MedlinePlus