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The pathways for intelligible speech: multivariate and univariate perspectives.

Evans S, Kyong JS, Rosen S, Golestani N, Warren JE, McGettigan C, Mourão-Miranda J, Wise RJ, Scott SK - Cereb. Cortex (2013)

Bottom Line: We have demonstrated that the left anterior superior temporal sulcus (STS) responds preferentially to intelligible speech (Scott SK, Blank CC, Rosen S, Wise RJS. 2000.In contrast, in classifications using local "searchlights" and a whole brain analysis, we find greater classification accuracy in posterior rather than anterior temporal regions.Thus, we show that the precise nature of the multivariate analysis used will emphasize different response profiles associated with complex sound to speech processing.

View Article: PubMed Central - PubMed

Affiliation: Institute of Cognitive Neuroscience, MRC Cognition and Brain Sciences Unit, Cambridge CB2 7EF, UK.

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Related in: MedlinePlus

Surface renderings of the main positive effect of spectral detail, peak level uncorrected P < 0.001, FDR cluster corrected at q < 0.05. Plots show the mean beta value with error bars representing the standard error of the mean corrected for repeated-measures comparisons. Note that since there was no implicit baseline, the plots are mean centered to the overall level of activation to all conditions.
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BHT083F1: Surface renderings of the main positive effect of spectral detail, peak level uncorrected P < 0.001, FDR cluster corrected at q < 0.05. Plots show the mean beta value with error bars representing the standard error of the mean corrected for repeated-measures comparisons. Note that since there was no implicit baseline, the plots are mean centered to the overall level of activation to all conditions.

Mentions: The main effect of spectral detail gave rise to bilateral clusters of activation focused within the PAC [12.3% in the left and 15.1% of the cluster in the right were located in PAC region TE 1.0 and 1.1 (Morosan et al. 2001)] and along the length of the superior temporal gyrus (STG; Fig. 1). Peak level activations were found in PAC and the STG bilaterally. This robustly bilateral activation contrasts with Scott et al. (2000), which evidenced a solely right lateralized response to the equivalent contrast. The increased power of this study, in which there were many more repetitions of the stimuli and measurements of the neural response, is likely to explain this difference.Figure 1.


The pathways for intelligible speech: multivariate and univariate perspectives.

Evans S, Kyong JS, Rosen S, Golestani N, Warren JE, McGettigan C, Mourão-Miranda J, Wise RJ, Scott SK - Cereb. Cortex (2013)

Surface renderings of the main positive effect of spectral detail, peak level uncorrected P < 0.001, FDR cluster corrected at q < 0.05. Plots show the mean beta value with error bars representing the standard error of the mean corrected for repeated-measures comparisons. Note that since there was no implicit baseline, the plots are mean centered to the overall level of activation to all conditions.
© Copyright Policy - creative-commons
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4128702&req=5

BHT083F1: Surface renderings of the main positive effect of spectral detail, peak level uncorrected P < 0.001, FDR cluster corrected at q < 0.05. Plots show the mean beta value with error bars representing the standard error of the mean corrected for repeated-measures comparisons. Note that since there was no implicit baseline, the plots are mean centered to the overall level of activation to all conditions.
Mentions: The main effect of spectral detail gave rise to bilateral clusters of activation focused within the PAC [12.3% in the left and 15.1% of the cluster in the right were located in PAC region TE 1.0 and 1.1 (Morosan et al. 2001)] and along the length of the superior temporal gyrus (STG; Fig. 1). Peak level activations were found in PAC and the STG bilaterally. This robustly bilateral activation contrasts with Scott et al. (2000), which evidenced a solely right lateralized response to the equivalent contrast. The increased power of this study, in which there were many more repetitions of the stimuli and measurements of the neural response, is likely to explain this difference.Figure 1.

Bottom Line: We have demonstrated that the left anterior superior temporal sulcus (STS) responds preferentially to intelligible speech (Scott SK, Blank CC, Rosen S, Wise RJS. 2000.In contrast, in classifications using local "searchlights" and a whole brain analysis, we find greater classification accuracy in posterior rather than anterior temporal regions.Thus, we show that the precise nature of the multivariate analysis used will emphasize different response profiles associated with complex sound to speech processing.

View Article: PubMed Central - PubMed

Affiliation: Institute of Cognitive Neuroscience, MRC Cognition and Brain Sciences Unit, Cambridge CB2 7EF, UK.

Show MeSH
Related in: MedlinePlus