The pathways for intelligible speech: multivariate and univariate perspectives.
Bottom Line: We have demonstrated that the left anterior superior temporal sulcus (STS) responds preferentially to intelligible speech (Scott SK, Blank CC, Rosen S, Wise RJS. 2000.In contrast, in classifications using local "searchlights" and a whole brain analysis, we find greater classification accuracy in posterior rather than anterior temporal regions.Thus, we show that the precise nature of the multivariate analysis used will emphasize different response profiles associated with complex sound to speech processing.
Affiliation: Institute of Cognitive Neuroscience, MRC Cognition and Brain Sciences Unit, Cambridge CB2 7EF, UK.Show MeSH
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Mentions: The main effect of spectral detail gave rise to bilateral clusters of activation focused within the PAC [12.3% in the left and 15.1% of the cluster in the right were located in PAC region TE 1.0 and 1.1 (Morosan et al. 2001)] and along the length of the superior temporal gyrus (STG; Fig. 1). Peak level activations were found in PAC and the STG bilaterally. This robustly bilateral activation contrasts with Scott et al. (2000), which evidenced a solely right lateralized response to the equivalent contrast. The increased power of this study, in which there were many more repetitions of the stimuli and measurements of the neural response, is likely to explain this difference.Figure 1.
Affiliation: Institute of Cognitive Neuroscience, MRC Cognition and Brain Sciences Unit, Cambridge CB2 7EF, UK.