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Multifocal bacterial osteomyelitis in a renal allograft recipient following urosepsis.

Valson AT, David VG, Balaji V, John GT - Indian J Nephrol (2014)

Bottom Line: Non-tubercular bacterial osteomyelitis is a rare infection.We report on a renal allograft recipient with osteomyelitis complicating urosepsis, manifesting as a multifocal infection poorly responsive to appropriate antibiotics and surgical intervention and culminating in graft loss.

View Article: PubMed Central - PubMed

Affiliation: Department of Nephrology, Christian Medical College Hospital, Vellore, Tamil Nadu, India.

ABSTRACT
Non-tubercular bacterial osteomyelitis is a rare infection. We report on a renal allograft recipient with osteomyelitis complicating urosepsis, manifesting as a multifocal infection poorly responsive to appropriate antibiotics and surgical intervention and culminating in graft loss.

No MeSH data available.


Related in: MedlinePlus

Technetium-99 methylene diphosphonate bone scan image of the patient, showing increased tracer uptake in both tibiae, shaft of humerii, femorii, ankle joints, iliac bones, sternoclavicular joint, lateral end of clavicle and corocoid process of scapulae (June 2007)
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Figure 2: Technetium-99 methylene diphosphonate bone scan image of the patient, showing increased tracer uptake in both tibiae, shaft of humerii, femorii, ankle joints, iliac bones, sternoclavicular joint, lateral end of clavicle and corocoid process of scapulae (June 2007)

Mentions: As both legs continued to suppurate, he underwent bilateral surgical decompression and insertion of gentamicin beads into the right tibia in February 2007. By June 2007, despite 7 months of IV imipenem, osteomyelitis had progressed to involve the ankles, humeri, iliac bones, scapula, sternum, clavicles and both femurs [Figure 2]. Radical limb amputation was not considered due to the multifocal nature of the disease. Azathioprine was withdrawn and Imipenem continued. In October 2007, he underwent sequestrectomy, curettage and gentamicin bead insertion for persistent left tibial discharge. A second course of valganciclovir was given for CMV retinitis without CMV viremia, following which the lesions healed.


Multifocal bacterial osteomyelitis in a renal allograft recipient following urosepsis.

Valson AT, David VG, Balaji V, John GT - Indian J Nephrol (2014)

Technetium-99 methylene diphosphonate bone scan image of the patient, showing increased tracer uptake in both tibiae, shaft of humerii, femorii, ankle joints, iliac bones, sternoclavicular joint, lateral end of clavicle and corocoid process of scapulae (June 2007)
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4127842&req=5

Figure 2: Technetium-99 methylene diphosphonate bone scan image of the patient, showing increased tracer uptake in both tibiae, shaft of humerii, femorii, ankle joints, iliac bones, sternoclavicular joint, lateral end of clavicle and corocoid process of scapulae (June 2007)
Mentions: As both legs continued to suppurate, he underwent bilateral surgical decompression and insertion of gentamicin beads into the right tibia in February 2007. By June 2007, despite 7 months of IV imipenem, osteomyelitis had progressed to involve the ankles, humeri, iliac bones, scapula, sternum, clavicles and both femurs [Figure 2]. Radical limb amputation was not considered due to the multifocal nature of the disease. Azathioprine was withdrawn and Imipenem continued. In October 2007, he underwent sequestrectomy, curettage and gentamicin bead insertion for persistent left tibial discharge. A second course of valganciclovir was given for CMV retinitis without CMV viremia, following which the lesions healed.

Bottom Line: Non-tubercular bacterial osteomyelitis is a rare infection.We report on a renal allograft recipient with osteomyelitis complicating urosepsis, manifesting as a multifocal infection poorly responsive to appropriate antibiotics and surgical intervention and culminating in graft loss.

View Article: PubMed Central - PubMed

Affiliation: Department of Nephrology, Christian Medical College Hospital, Vellore, Tamil Nadu, India.

ABSTRACT
Non-tubercular bacterial osteomyelitis is a rare infection. We report on a renal allograft recipient with osteomyelitis complicating urosepsis, manifesting as a multifocal infection poorly responsive to appropriate antibiotics and surgical intervention and culminating in graft loss.

No MeSH data available.


Related in: MedlinePlus