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Intensification of bioactive compounds extraction from medicinal plants using ultrasonic irradiation.

Vardanega R, Santos DT, Meireles MA - Pharmacogn Rev (2014)

Bottom Line: Extraction processes are largely used in many chemical, biotechnological and pharmaceutical industries for recovery of bioactive compounds from medicinal plants.To replace the conventional extraction techniques, new techniques as high-pressure extraction processes that use environment friendly solvents have been developed.However, these techniques, sometimes, are associated with low extraction rate.

View Article: PubMed Central - PubMed

Affiliation: LASEFI/DEA/FEA (School of Food Engineering), UNICAMP (University of Campinas), SP, Brazil.

ABSTRACT
Extraction processes are largely used in many chemical, biotechnological and pharmaceutical industries for recovery of bioactive compounds from medicinal plants. To replace the conventional extraction techniques, new techniques as high-pressure extraction processes that use environment friendly solvents have been developed. However, these techniques, sometimes, are associated with low extraction rate. The ultrasound can be effectively used to improve the extraction rate by the increasing the mass transfer and possible rupture of cell wall due the formation of microcavities leading to higher product yields with reduced processing time and solvent consumption. This review presents a brief survey about the mechanism and aspects that affecting the ultrasound assisted extraction focusing on the use of ultrasound irradiation for high-pressure extraction processes intensification.

No MeSH data available.


Related in: MedlinePlus

Collapse of cavitation bubble and release of plant content (adapted from Pingret et al.[3])
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Figure 1: Collapse of cavitation bubble and release of plant content (adapted from Pingret et al.[3])

Mentions: Ultrasound also exerts a mechanical effect. In pure liquids, the bubble retains its spherical shape during the collapse, as its surroundings are uniform. However, when the bubble collapses near a solid surface it occurs asymmetrically and produces high-speed jets of solvent toward the cell walls. These jets have a strong impact on the solid surface, therefore, increasing the solvent penetration into the cell and increasing the contact surface area between solid and liquid phase [Figure 1].[46] Another effect caused by the ultrasound wave on the solid material is that the ultrasound waves can facilitate the swelling and hydration and so cause an enlargement in the pores of the cell wall. This will improve the diffusion process and therefore enhancing mass transfer.[7]


Intensification of bioactive compounds extraction from medicinal plants using ultrasonic irradiation.

Vardanega R, Santos DT, Meireles MA - Pharmacogn Rev (2014)

Collapse of cavitation bubble and release of plant content (adapted from Pingret et al.[3])
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4127826&req=5

Figure 1: Collapse of cavitation bubble and release of plant content (adapted from Pingret et al.[3])
Mentions: Ultrasound also exerts a mechanical effect. In pure liquids, the bubble retains its spherical shape during the collapse, as its surroundings are uniform. However, when the bubble collapses near a solid surface it occurs asymmetrically and produces high-speed jets of solvent toward the cell walls. These jets have a strong impact on the solid surface, therefore, increasing the solvent penetration into the cell and increasing the contact surface area between solid and liquid phase [Figure 1].[46] Another effect caused by the ultrasound wave on the solid material is that the ultrasound waves can facilitate the swelling and hydration and so cause an enlargement in the pores of the cell wall. This will improve the diffusion process and therefore enhancing mass transfer.[7]

Bottom Line: Extraction processes are largely used in many chemical, biotechnological and pharmaceutical industries for recovery of bioactive compounds from medicinal plants.To replace the conventional extraction techniques, new techniques as high-pressure extraction processes that use environment friendly solvents have been developed.However, these techniques, sometimes, are associated with low extraction rate.

View Article: PubMed Central - PubMed

Affiliation: LASEFI/DEA/FEA (School of Food Engineering), UNICAMP (University of Campinas), SP, Brazil.

ABSTRACT
Extraction processes are largely used in many chemical, biotechnological and pharmaceutical industries for recovery of bioactive compounds from medicinal plants. To replace the conventional extraction techniques, new techniques as high-pressure extraction processes that use environment friendly solvents have been developed. However, these techniques, sometimes, are associated with low extraction rate. The ultrasound can be effectively used to improve the extraction rate by the increasing the mass transfer and possible rupture of cell wall due the formation of microcavities leading to higher product yields with reduced processing time and solvent consumption. This review presents a brief survey about the mechanism and aspects that affecting the ultrasound assisted extraction focusing on the use of ultrasound irradiation for high-pressure extraction processes intensification.

No MeSH data available.


Related in: MedlinePlus