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The effect of a community-based, primary health care exercise program on inflammatory biomarkers and hormone levels.

Papini CB, Nakamura PM, Zorzetto LP, Thompson JL, Phillips AC, Kokubun E - Mediators Inflamm. (2014)

Bottom Line: Repeated measures ANOVA analyses indicated that the intervention was effective in reducing CRP and TNFα after 1 year compared to baseline and 6 months (P < 0.05).There were no changes in IL10, IL6, and insulin after 1 year.However, leptin significantly increased at 1 year (P = 0.016).

View Article: PubMed Central - PubMed

Affiliation: Department of Physical Education, São Paulo State University, Avenida 24-A, 1515 Bela Vista, 13506-900 Rio Claro, SP, Brazil.

ABSTRACT
The aim of this study was to analyze the impact of a community-based exercise program in primary care on inflammatory biomarkers and hormone levels. The 1-year quasiexperimental study involved 13 women (mean age = 56.8 ± 11.4 years) and it was developed in two basic health care units in Rio Claro City, Brazil. The physical exercise intervention was comprised of two, 60-minute sessions/week. The inflammatory biomarkers were measured at baseline, 6 months, and 1 year. Repeated measures ANOVA analyses indicated that the intervention was effective in reducing CRP and TNFα after 1 year compared to baseline and 6 months (P < 0.05). There were no changes in IL10, IL6, and insulin after 1 year. However, leptin significantly increased at 1 year (P = 0.016). The major finding of this study is that a community-based exercise program can result in a decrease or maintenance of inflammatory biomarkers after 1 year, and thus has the potential to be a viable public health approach for chronic disease prevention.

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Related in: MedlinePlus

Recruitment of participants for the study. Evaluations were done at baseline, 6 months, and 1 year of SARC intervention.
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Related In: Results  -  Collection


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fig1: Recruitment of participants for the study. Evaluations were done at baseline, 6 months, and 1 year of SARC intervention.

Mentions: This 1-year quasiexperimental study was developed in two basic health care units in Rio Claro City, Brazil. Adult females were recruited via flyers and newspaper advertisements. Participants were assigned to the intervention group based upon proximity from their residence. Thirty-six participants were recruited at the beginning of intervention. As a result of either voluntary dropout or failure to meet the inclusion criterion for the study (frequency of 75% attendance in the sessions), 25 participants remained in the intervention after 6 months. Although 17 participants completed the 1 year intervention, four participants did not complete all evaluations; thus the final sample size was 13 women (mean age = 56.8 ± 11.4 years, Figure 1). The study was approved by the Human Research Ethics Committee of Biosciences Institute, UNESP, protocol number: 2308.


The effect of a community-based, primary health care exercise program on inflammatory biomarkers and hormone levels.

Papini CB, Nakamura PM, Zorzetto LP, Thompson JL, Phillips AC, Kokubun E - Mediators Inflamm. (2014)

Recruitment of participants for the study. Evaluations were done at baseline, 6 months, and 1 year of SARC intervention.
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4127245&req=5

fig1: Recruitment of participants for the study. Evaluations were done at baseline, 6 months, and 1 year of SARC intervention.
Mentions: This 1-year quasiexperimental study was developed in two basic health care units in Rio Claro City, Brazil. Adult females were recruited via flyers and newspaper advertisements. Participants were assigned to the intervention group based upon proximity from their residence. Thirty-six participants were recruited at the beginning of intervention. As a result of either voluntary dropout or failure to meet the inclusion criterion for the study (frequency of 75% attendance in the sessions), 25 participants remained in the intervention after 6 months. Although 17 participants completed the 1 year intervention, four participants did not complete all evaluations; thus the final sample size was 13 women (mean age = 56.8 ± 11.4 years, Figure 1). The study was approved by the Human Research Ethics Committee of Biosciences Institute, UNESP, protocol number: 2308.

Bottom Line: Repeated measures ANOVA analyses indicated that the intervention was effective in reducing CRP and TNFα after 1 year compared to baseline and 6 months (P < 0.05).There were no changes in IL10, IL6, and insulin after 1 year.However, leptin significantly increased at 1 year (P = 0.016).

View Article: PubMed Central - PubMed

Affiliation: Department of Physical Education, São Paulo State University, Avenida 24-A, 1515 Bela Vista, 13506-900 Rio Claro, SP, Brazil.

ABSTRACT
The aim of this study was to analyze the impact of a community-based exercise program in primary care on inflammatory biomarkers and hormone levels. The 1-year quasiexperimental study involved 13 women (mean age = 56.8 ± 11.4 years) and it was developed in two basic health care units in Rio Claro City, Brazil. The physical exercise intervention was comprised of two, 60-minute sessions/week. The inflammatory biomarkers were measured at baseline, 6 months, and 1 year. Repeated measures ANOVA analyses indicated that the intervention was effective in reducing CRP and TNFα after 1 year compared to baseline and 6 months (P < 0.05). There were no changes in IL10, IL6, and insulin after 1 year. However, leptin significantly increased at 1 year (P = 0.016). The major finding of this study is that a community-based exercise program can result in a decrease or maintenance of inflammatory biomarkers after 1 year, and thus has the potential to be a viable public health approach for chronic disease prevention.

Show MeSH
Related in: MedlinePlus