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Correction: Nsp9 and Nsp10 Contribute to the Fatal Virulence of Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus Emerging in China

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Growth kinetics of the rescued viruses with the exchanged Nsp-coding region within ORF1b.The growth curves of each chimeric virus, RvJXwn and RvHB-1/3.9 in MARC-145 cells (A, B, C and D) and in primary PAMs (E, F, G and H) are shown. Virus titers from 12 h to 96 h pi were determined by microtitration infectivity assays. The data are shown as the means ± standard deviations (error bars) from three independent trials. Asterisk (*) indicates a significant difference in virus titers between RvJXwn (red) and RvJHn9 (black), or RvJHn9n10 (green), or between RvHB-1/3.9 (blue) and RvHJn9 (black) or RvHJn9n10 (green) (*P<0.05; **P<0.01; ***P<0.001). Pound (#) indicates a significant difference between RvJXwn and RvJHn10 (light blue) or RvJHn9n10n11 (yellow), or between RvHB-1/3.9 and RvHJn10 (light blue) or RvHJn9n10n11 (yellow) (##P<0.01; ###P<0.001). Phi (Φ) indicates a significant difference between RvHB-1/3.9 and RvHJn11 (gray) (ΦΦP<0.01; ΦΦΦP<0.001). Delta (δ) indicates a significant difference between RvHB-1/3.9 and RvHJn12 (gray) (δP<0.05; δδP<0.01). doi:10.1371/journal.ppat.1004216.g005
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ppat-1004344-g001: Growth kinetics of the rescued viruses with the exchanged Nsp-coding region within ORF1b.The growth curves of each chimeric virus, RvJXwn and RvHB-1/3.9 in MARC-145 cells (A, B, C and D) and in primary PAMs (E, F, G and H) are shown. Virus titers from 12 h to 96 h pi were determined by microtitration infectivity assays. The data are shown as the means ± standard deviations (error bars) from three independent trials. Asterisk (*) indicates a significant difference in virus titers between RvJXwn (red) and RvJHn9 (black), or RvJHn9n10 (green), or between RvHB-1/3.9 (blue) and RvHJn9 (black) or RvHJn9n10 (green) (*P<0.05; **P<0.01; ***P<0.001). Pound (#) indicates a significant difference between RvJXwn and RvJHn10 (light blue) or RvJHn9n10n11 (yellow), or between RvHB-1/3.9 and RvHJn10 (light blue) or RvHJn9n10n11 (yellow) (##P<0.01; ###P<0.001). Phi (Φ) indicates a significant difference between RvHB-1/3.9 and RvHJn11 (gray) (ΦΦP<0.01; ΦΦΦP<0.001). Delta (δ) indicates a significant difference between RvHB-1/3.9 and RvHJn12 (gray) (δP<0.05; δδP<0.01). doi:10.1371/journal.ppat.1004216.g005

Mentions: The incorrect version of Figure 5 was published. The icons showing RvHJn9 and RvHJn11 in panel C are now consistent with the icons in panel G. Please see the corrected figure here.


Correction: Nsp9 and Nsp10 Contribute to the Fatal Virulence of Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus Emerging in China
Growth kinetics of the rescued viruses with the exchanged Nsp-coding region within ORF1b.The growth curves of each chimeric virus, RvJXwn and RvHB-1/3.9 in MARC-145 cells (A, B, C and D) and in primary PAMs (E, F, G and H) are shown. Virus titers from 12 h to 96 h pi were determined by microtitration infectivity assays. The data are shown as the means ± standard deviations (error bars) from three independent trials. Asterisk (*) indicates a significant difference in virus titers between RvJXwn (red) and RvJHn9 (black), or RvJHn9n10 (green), or between RvHB-1/3.9 (blue) and RvHJn9 (black) or RvHJn9n10 (green) (*P<0.05; **P<0.01; ***P<0.001). Pound (#) indicates a significant difference between RvJXwn and RvJHn10 (light blue) or RvJHn9n10n11 (yellow), or between RvHB-1/3.9 and RvHJn10 (light blue) or RvHJn9n10n11 (yellow) (##P<0.01; ###P<0.001). Phi (Φ) indicates a significant difference between RvHB-1/3.9 and RvHJn11 (gray) (ΦΦP<0.01; ΦΦΦP<0.001). Delta (δ) indicates a significant difference between RvHB-1/3.9 and RvHJn12 (gray) (δP<0.05; δδP<0.01). doi:10.1371/journal.ppat.1004216.g005
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ppat-1004344-g001: Growth kinetics of the rescued viruses with the exchanged Nsp-coding region within ORF1b.The growth curves of each chimeric virus, RvJXwn and RvHB-1/3.9 in MARC-145 cells (A, B, C and D) and in primary PAMs (E, F, G and H) are shown. Virus titers from 12 h to 96 h pi were determined by microtitration infectivity assays. The data are shown as the means ± standard deviations (error bars) from three independent trials. Asterisk (*) indicates a significant difference in virus titers between RvJXwn (red) and RvJHn9 (black), or RvJHn9n10 (green), or between RvHB-1/3.9 (blue) and RvHJn9 (black) or RvHJn9n10 (green) (*P<0.05; **P<0.01; ***P<0.001). Pound (#) indicates a significant difference between RvJXwn and RvJHn10 (light blue) or RvJHn9n10n11 (yellow), or between RvHB-1/3.9 and RvHJn10 (light blue) or RvHJn9n10n11 (yellow) (##P<0.01; ###P<0.001). Phi (Φ) indicates a significant difference between RvHB-1/3.9 and RvHJn11 (gray) (ΦΦP<0.01; ΦΦΦP<0.001). Delta (δ) indicates a significant difference between RvHB-1/3.9 and RvHJn12 (gray) (δP<0.05; δδP<0.01). doi:10.1371/journal.ppat.1004216.g005
Mentions: The incorrect version of Figure 5 was published. The icons showing RvHJn9 and RvHJn11 in panel C are now consistent with the icons in panel G. Please see the corrected figure here.

View Article: PubMed Central

No MeSH data available.


Related in: MedlinePlus