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Bioresorbable vascular scaffold use in a case of in-stent restenosis.

Cadrin-Tourigny J, Dong L, Maehara A, Schampaert E, Genereux P - Arq. Bras. Cardiol. (2014)

View Article: PubMed Central - PubMed

Affiliation: Hôpital du Sacré-Coeur de Montréal, Québec, Canada.

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Bare metal stent Bioresorbable vascular scaffold Drug-eluting stent In-stent restenosis Left anterior descending Optical coherence tomography Percutaneous coronary intervention Bioresorbable vascular scaffolds (BVS) demonstrate favourable outcomes in patients with We present the first case of in-stent restenosis (ISR) successfully treated with an everolimus-eluting BVS (ABSORB; Abbott Vascular, Santa He had undergone PCI of the proximal left anterior descending everolimus... Prospective studies of BVS showed favourable outcomes in simple, de novo However, these studies specifically excluded ISR lesions... characterized by late lumen enlargement and replacement of the platform by proteoglycans, resulting in filling of the micro-aneurysms and exclusion of the nidus BVS are a promising addition to the PCI arsenal in managing complex coronary lesions... This case report demonstrates novel use of this technology to treat an ISR lesion of DES characterized by late acquired malapposition.

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Post PCI Angiogram and Optical Coherence Tomography(A) Final coronary angiography showing exclusion of the 2 micro-aneurysms presentat baseline. (B) Final optical coherence tomography showing good BVS appositionwith covering of the 2 micro-aneurysms and thrombus entrapment.
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f02: Post PCI Angiogram and Optical Coherence Tomography(A) Final coronary angiography showing exclusion of the 2 micro-aneurysms presentat baseline. (B) Final optical coherence tomography showing good BVS appositionwith covering of the 2 micro-aneurysms and thrombus entrapment.

Mentions: The coronary angiogram showed a severe 95% ISR lesion of the proximal LAD with thrombusand multiple areas of contrast staining outside the stent contour, compatible withcoronary micro-aneurysms (Figure 1A).Thromboaspiration revealed white thrombus. Optical coherence tomography (OCT) wascompatible with a localized hypersensitivity reaction to first-generation DES (Figure 1B). After consensus with the referringphysician, an ABSORB everolimus-eluting BVS 3.0 x 18 mm was deployed (Figure 2A). Repeated OCT showed good scaffoldapposition and coverage of the micro-aneurysms (Figure2B). The patient was discharged the following day on dual antiplatelet therapywith aspirin and ticagrelor. The patient was asymptomatic at 6 months clinicalfollow-up.


Bioresorbable vascular scaffold use in a case of in-stent restenosis.

Cadrin-Tourigny J, Dong L, Maehara A, Schampaert E, Genereux P - Arq. Bras. Cardiol. (2014)

Post PCI Angiogram and Optical Coherence Tomography(A) Final coronary angiography showing exclusion of the 2 micro-aneurysms presentat baseline. (B) Final optical coherence tomography showing good BVS appositionwith covering of the 2 micro-aneurysms and thrombus entrapment.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4126766&req=5

f02: Post PCI Angiogram and Optical Coherence Tomography(A) Final coronary angiography showing exclusion of the 2 micro-aneurysms presentat baseline. (B) Final optical coherence tomography showing good BVS appositionwith covering of the 2 micro-aneurysms and thrombus entrapment.
Mentions: The coronary angiogram showed a severe 95% ISR lesion of the proximal LAD with thrombusand multiple areas of contrast staining outside the stent contour, compatible withcoronary micro-aneurysms (Figure 1A).Thromboaspiration revealed white thrombus. Optical coherence tomography (OCT) wascompatible with a localized hypersensitivity reaction to first-generation DES (Figure 1B). After consensus with the referringphysician, an ABSORB everolimus-eluting BVS 3.0 x 18 mm was deployed (Figure 2A). Repeated OCT showed good scaffoldapposition and coverage of the micro-aneurysms (Figure2B). The patient was discharged the following day on dual antiplatelet therapywith aspirin and ticagrelor. The patient was asymptomatic at 6 months clinicalfollow-up.

View Article: PubMed Central - PubMed

Affiliation: Hôpital du Sacré-Coeur de Montréal, Québec, Canada.

AUTOMATICALLY GENERATED EXCERPT
Please rate it.

Bare metal stent Bioresorbable vascular scaffold Drug-eluting stent In-stent restenosis Left anterior descending Optical coherence tomography Percutaneous coronary intervention Bioresorbable vascular scaffolds (BVS) demonstrate favourable outcomes in patients with We present the first case of in-stent restenosis (ISR) successfully treated with an everolimus-eluting BVS (ABSORB; Abbott Vascular, Santa He had undergone PCI of the proximal left anterior descending everolimus... Prospective studies of BVS showed favourable outcomes in simple, de novo However, these studies specifically excluded ISR lesions... characterized by late lumen enlargement and replacement of the platform by proteoglycans, resulting in filling of the micro-aneurysms and exclusion of the nidus BVS are a promising addition to the PCI arsenal in managing complex coronary lesions... This case report demonstrates novel use of this technology to treat an ISR lesion of DES characterized by late acquired malapposition.

Show MeSH
Related in: MedlinePlus