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Bone tumor mimickers: A pictorial essay.

Mhuircheartaigh JN, Lin YC, Wu JS - Indian J Radiol Imaging (2014)

Bottom Line: These bone tumor mimickers can include numerous normal anatomic variants and non-neoplastic processes.It is important for the radiologist and clinician to be aware of these bone tumor mimickers and understand the characteristic features which allow discrimination between them and true neoplasms in order to avoid unnecessary additional workup.Knowing which lesions to leave alone or which ones require workup can prevent misdiagnosis and reduce patient anxiety.

View Article: PubMed Central - PubMed

Affiliation: Department of Radiology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States.

ABSTRACT
Focal lesions in bone are very common and many of these lesions are not bone tumors. These bone tumor mimickers can include numerous normal anatomic variants and non-neoplastic processes. Many of these tumor mimickers can be left alone, while others can be due to a significant disease process. It is important for the radiologist and clinician to be aware of these bone tumor mimickers and understand the characteristic features which allow discrimination between them and true neoplasms in order to avoid unnecessary additional workup. Knowing which lesions to leave alone or which ones require workup can prevent misdiagnosis and reduce patient anxiety.

No MeSH data available.


Related in: MedlinePlus

Brown tumor of hyperparathyroidism. A 42-year-old female with history of parathyroid adenoma. Focused AP radiograph of the humerus shows multiple well-defined lytic lesions (arrows) in the right humeral shaft
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Figure 18: Brown tumor of hyperparathyroidism. A 42-year-old female with history of parathyroid adenoma. Focused AP radiograph of the humerus shows multiple well-defined lytic lesions (arrows) in the right humeral shaft

Mentions: Longstanding untreated hyperparathyroidism can result in osteolytic lesions known as brown tumors (osteoclastomas) [Figure 18]. They can be seen in either primary or secondary hyperparathyroidism and are seen in 5% of patients with hyperparathyroidism.[32] However, the incidence has decreased with improved early diagnosis of the disease. The typical appearance of a brown tumor is a well-defined osteolytic lesion, which may have septations, be expansile, and can sometimes have aggressive features. Common sites include the long bones, ribs, pelvis, and facial bones.[33] The lesions improve with treatment, often becoming sclerotic. If lesions fail to improve in appearance with treatment, an alternative diagnosis should be considered.


Bone tumor mimickers: A pictorial essay.

Mhuircheartaigh JN, Lin YC, Wu JS - Indian J Radiol Imaging (2014)

Brown tumor of hyperparathyroidism. A 42-year-old female with history of parathyroid adenoma. Focused AP radiograph of the humerus shows multiple well-defined lytic lesions (arrows) in the right humeral shaft
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4126137&req=5

Figure 18: Brown tumor of hyperparathyroidism. A 42-year-old female with history of parathyroid adenoma. Focused AP radiograph of the humerus shows multiple well-defined lytic lesions (arrows) in the right humeral shaft
Mentions: Longstanding untreated hyperparathyroidism can result in osteolytic lesions known as brown tumors (osteoclastomas) [Figure 18]. They can be seen in either primary or secondary hyperparathyroidism and are seen in 5% of patients with hyperparathyroidism.[32] However, the incidence has decreased with improved early diagnosis of the disease. The typical appearance of a brown tumor is a well-defined osteolytic lesion, which may have septations, be expansile, and can sometimes have aggressive features. Common sites include the long bones, ribs, pelvis, and facial bones.[33] The lesions improve with treatment, often becoming sclerotic. If lesions fail to improve in appearance with treatment, an alternative diagnosis should be considered.

Bottom Line: These bone tumor mimickers can include numerous normal anatomic variants and non-neoplastic processes.It is important for the radiologist and clinician to be aware of these bone tumor mimickers and understand the characteristic features which allow discrimination between them and true neoplasms in order to avoid unnecessary additional workup.Knowing which lesions to leave alone or which ones require workup can prevent misdiagnosis and reduce patient anxiety.

View Article: PubMed Central - PubMed

Affiliation: Department of Radiology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States.

ABSTRACT
Focal lesions in bone are very common and many of these lesions are not bone tumors. These bone tumor mimickers can include numerous normal anatomic variants and non-neoplastic processes. Many of these tumor mimickers can be left alone, while others can be due to a significant disease process. It is important for the radiologist and clinician to be aware of these bone tumor mimickers and understand the characteristic features which allow discrimination between them and true neoplasms in order to avoid unnecessary additional workup. Knowing which lesions to leave alone or which ones require workup can prevent misdiagnosis and reduce patient anxiety.

No MeSH data available.


Related in: MedlinePlus