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Bone tumor mimickers: A pictorial essay.

Mhuircheartaigh JN, Lin YC, Wu JS - Indian J Radiol Imaging (2014)

Bottom Line: These bone tumor mimickers can include numerous normal anatomic variants and non-neoplastic processes.It is important for the radiologist and clinician to be aware of these bone tumor mimickers and understand the characteristic features which allow discrimination between them and true neoplasms in order to avoid unnecessary additional workup.Knowing which lesions to leave alone or which ones require workup can prevent misdiagnosis and reduce patient anxiety.

View Article: PubMed Central - PubMed

Affiliation: Department of Radiology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States.

ABSTRACT
Focal lesions in bone are very common and many of these lesions are not bone tumors. These bone tumor mimickers can include numerous normal anatomic variants and non-neoplastic processes. Many of these tumor mimickers can be left alone, while others can be due to a significant disease process. It is important for the radiologist and clinician to be aware of these bone tumor mimickers and understand the characteristic features which allow discrimination between them and true neoplasms in order to avoid unnecessary additional workup. Knowing which lesions to leave alone or which ones require workup can prevent misdiagnosis and reduce patient anxiety.

No MeSH data available.


Related in: MedlinePlus

Particle disease. An 82 year old male who had undergone total hip replacement for hip pain. (A) AP radiograph of the right hip shows multiple lucent lesions (arrows) on both sides of the right hip joint, abutting both the femoral and acetabular components (B) Axial CT image demonstrates multiple cavities (arrows) around the prosthesis, which do not confine to the outline of the prosthesis
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Figure 16: Particle disease. An 82 year old male who had undergone total hip replacement for hip pain. (A) AP radiograph of the right hip shows multiple lucent lesions (arrows) on both sides of the right hip joint, abutting both the femoral and acetabular components (B) Axial CT image demonstrates multiple cavities (arrows) around the prosthesis, which do not confine to the outline of the prosthesis

Mentions: Particle disease can present as areas of radiolucency surrounding the hardware components, usually following arthroplasty.[28] However, unlike mechanical loosening, the lucent areas seen with particle disease typically do not follow the outline of the prosthesis [Figure 16].[29] The arthroplasty components can incite a macrophage-mediated granulomatous response, which then stimulates osteoclast activity.[28] Particle disease can mimic osteolytic tumors or infection; however, particle disease can be distinguished by the presence of hardware and the fact that abnormal lucencies are seen on both sides of a joint.


Bone tumor mimickers: A pictorial essay.

Mhuircheartaigh JN, Lin YC, Wu JS - Indian J Radiol Imaging (2014)

Particle disease. An 82 year old male who had undergone total hip replacement for hip pain. (A) AP radiograph of the right hip shows multiple lucent lesions (arrows) on both sides of the right hip joint, abutting both the femoral and acetabular components (B) Axial CT image demonstrates multiple cavities (arrows) around the prosthesis, which do not confine to the outline of the prosthesis
© Copyright Policy - open-access
Related In: Results  -  Collection

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getmorefigures.php?uid=PMC4126137&req=5

Figure 16: Particle disease. An 82 year old male who had undergone total hip replacement for hip pain. (A) AP radiograph of the right hip shows multiple lucent lesions (arrows) on both sides of the right hip joint, abutting both the femoral and acetabular components (B) Axial CT image demonstrates multiple cavities (arrows) around the prosthesis, which do not confine to the outline of the prosthesis
Mentions: Particle disease can present as areas of radiolucency surrounding the hardware components, usually following arthroplasty.[28] However, unlike mechanical loosening, the lucent areas seen with particle disease typically do not follow the outline of the prosthesis [Figure 16].[29] The arthroplasty components can incite a macrophage-mediated granulomatous response, which then stimulates osteoclast activity.[28] Particle disease can mimic osteolytic tumors or infection; however, particle disease can be distinguished by the presence of hardware and the fact that abnormal lucencies are seen on both sides of a joint.

Bottom Line: These bone tumor mimickers can include numerous normal anatomic variants and non-neoplastic processes.It is important for the radiologist and clinician to be aware of these bone tumor mimickers and understand the characteristic features which allow discrimination between them and true neoplasms in order to avoid unnecessary additional workup.Knowing which lesions to leave alone or which ones require workup can prevent misdiagnosis and reduce patient anxiety.

View Article: PubMed Central - PubMed

Affiliation: Department of Radiology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States.

ABSTRACT
Focal lesions in bone are very common and many of these lesions are not bone tumors. These bone tumor mimickers can include numerous normal anatomic variants and non-neoplastic processes. Many of these tumor mimickers can be left alone, while others can be due to a significant disease process. It is important for the radiologist and clinician to be aware of these bone tumor mimickers and understand the characteristic features which allow discrimination between them and true neoplasms in order to avoid unnecessary additional workup. Knowing which lesions to leave alone or which ones require workup can prevent misdiagnosis and reduce patient anxiety.

No MeSH data available.


Related in: MedlinePlus