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Study of the digital model of self-regulation system of the heart

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With development of cardiology technologies relevant models of the cardiovascular system, taking into account the regulatory processes should be implemented. of the paper was to study the mathematical model of the system of self-regulation of the heart... The mathematical equation (1) allows us to consider the work of such a system is dependent on the values of the coefficients. (1) where: V1 - heart ventricle filling, V2 - stroke volume, P2 - the average pressure in aorta, Vres - residual blood volume, Vn - the cavity volume which “heterometric dependence” of the heart function starts from, K - pump ventricular coefficient, K7 - depending on the inertia heterometric ratio, K8 - the coefficient of inertia of “heterometric dependence” We estimated parameters and variables obtained from healthy volunteers... The form has a smooth transient nature of overshoot is observed... The results were similar for different signs of stress (+122, -122) and the magnitude of the perturbation... If K7 is less than 0.5, the control error, is less than 25% even at the maximum of unfavorable perturbation (kind of trigger effect - acceleration curve)... For a perturbation of the system of self-regulation of the heart are associated with changes in blood pressure, the coefficient K does not bind significantly to the transition process... The parameter that determines the heterometric depending inertia (K8), affects the output of the system time to a steady value (fig. 1)... If K8> 0, 5, then the observed oscillatory process is not consistent as physiological representations... The coefficient K7 has very little effect on the system when the pressure in the aorta... The inertia related to both heterometric and gemeometrical properties play a significant role in the dynamics of the heart... Using a mathematical model of the cardiovascular system with implemented regulation processes monitoring, and real-time operating computer systems can support personalized therapy... Similarly, qualitative analysis is required to select the appropriate therapy.

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the reaction of the model to a step of pressure change
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Figure 1: the reaction of the model to a step of pressure change

Mentions: For a perturbation of the system of self-regulation of the heart are associated with changes in blood pressure, the coefficient K does not bind significantly to the transition process. The parameter that determines the heterometric depending inertia (K8), affects the output of the system time to a steady value (fig. 1). If K8> 0, 5, then the observed oscillatory process is not consistent as physiological representations [3]. The coefficient K7 has very little effect on the system when the pressure in the aorta.


Study of the digital model of self-regulation system of the heart
the reaction of the model to a step of pressure change
© Copyright Policy - open-access
Related In: Results  -  Collection

License 1 - License 2
Show All Figures
getmorefigures.php?uid=PMC4125785&req=5

Figure 1: the reaction of the model to a step of pressure change
Mentions: For a perturbation of the system of self-regulation of the heart are associated with changes in blood pressure, the coefficient K does not bind significantly to the transition process. The parameter that determines the heterometric depending inertia (K8), affects the output of the system time to a steady value (fig. 1). If K8> 0, 5, then the observed oscillatory process is not consistent as physiological representations [3]. The coefficient K7 has very little effect on the system when the pressure in the aorta.

View Article: PubMed Central - HTML

AUTOMATICALLY GENERATED EXCERPT
Please rate it.

With development of cardiology technologies relevant models of the cardiovascular system, taking into account the regulatory processes should be implemented. of the paper was to study the mathematical model of the system of self-regulation of the heart... The mathematical equation (1) allows us to consider the work of such a system is dependent on the values of the coefficients. (1) where: V1 - heart ventricle filling, V2 - stroke volume, P2 - the average pressure in aorta, Vres - residual blood volume, Vn - the cavity volume which “heterometric dependence” of the heart function starts from, K - pump ventricular coefficient, K7 - depending on the inertia heterometric ratio, K8 - the coefficient of inertia of “heterometric dependence” We estimated parameters and variables obtained from healthy volunteers... The form has a smooth transient nature of overshoot is observed... The results were similar for different signs of stress (+122, -122) and the magnitude of the perturbation... If K7 is less than 0.5, the control error, is less than 25% even at the maximum of unfavorable perturbation (kind of trigger effect - acceleration curve)... For a perturbation of the system of self-regulation of the heart are associated with changes in blood pressure, the coefficient K does not bind significantly to the transition process... The parameter that determines the heterometric depending inertia (K8), affects the output of the system time to a steady value (fig. 1)... If K8> 0, 5, then the observed oscillatory process is not consistent as physiological representations... The coefficient K7 has very little effect on the system when the pressure in the aorta... The inertia related to both heterometric and gemeometrical properties play a significant role in the dynamics of the heart... Using a mathematical model of the cardiovascular system with implemented regulation processes monitoring, and real-time operating computer systems can support personalized therapy... Similarly, qualitative analysis is required to select the appropriate therapy.

No MeSH data available.