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The use of platelet rich plasma in the treatment of immature tooth with periapical lesion: a case report.

Güven Polat G, Yıldırım C, Akgün OM, Altun C, Dinçer D, Ozkan CK - Restor Dent Endod (2014)

Bottom Line: This study describes the treatment of an immature permanent tooth with periapical lesion which was treated with regenerative approach using platelet rich plasma (PRP).The root canal of immature human permanent tooth with periapical lesion was gently debrided of necrotic tissue and disinfected with 2.5% NaOCl, and then medicated with triple antibiotic paste comprised of ciprofloxacin, metronidazole, and tetracycline.Our findings suggest that PRP can be used for the treatment of immature permanent teeth with periapical lesion, as part of a regenerative endodontic treatment procedure.

View Article: PubMed Central - PubMed

Affiliation: Department of Pediatric Dentistry, Center for Dental Sciences, Gulhane Medical Academy, Ankara, Turkey.

ABSTRACT
This study describes the treatment of an immature permanent tooth with periapical lesion which was treated with regenerative approach using platelet rich plasma (PRP). The root canal of immature human permanent tooth with periapical lesion was gently debrided of necrotic tissue and disinfected with 2.5% NaOCl, and then medicated with triple antibiotic paste comprised of ciprofloxacin, metronidazole, and tetracycline. When the tooth was asymptomatic, PRP and mineral trioxide aggregate (MTA) were placed into the root canal. Six months after PRP treatment, radiographical examination revealed resolution of the radiolucency and progressive thickening of the root wall and apical closure. Our findings suggest that PRP can be used for the treatment of immature permanent teeth with periapical lesion, as part of a regenerative endodontic treatment procedure.

No MeSH data available.


Related in: MedlinePlus

Periapical radiograph of the left permanent mandibular second premolar six months after treatment.
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Figure 3: Periapical radiograph of the left permanent mandibular second premolar six months after treatment.

Mentions: The root canal was irrigated with sterile saline solution and dried with sterile paper points under rubber dam isolation. Then, PRP was injected gently into the root canal to the level of cemento-enamel junction (CEJ) using an insulin syringe, and allowed to clot for 10 minutes. MTA (Pro-Root MTA, Dentsply Maillefer, Baillagues, Switzerland) was then placed into the root canal with a wet cotton pellet placed over. The cotton pellet was removed after 10 minutes. Glass ionomer cement was placed against the MTA, and adhesive (Excite DSC, Ivoclar Vivadent AG, Schaan, Liechtenstein) was applied according to the manufacturer's instructions. Finally, composite restoration was completed with Tetric Ceram (Ivoclar Vivadent AG) using the incremental technique, followed by occlusal adjustment (Figure 2). The patient was asymptomatic six months after the treatment. The radiographic presentation of the radiolucency was healed and the root continued to develop (Figure 3). At the 2-year recall, the root of the tooth was fully developed (Figure 4).


The use of platelet rich plasma in the treatment of immature tooth with periapical lesion: a case report.

Güven Polat G, Yıldırım C, Akgün OM, Altun C, Dinçer D, Ozkan CK - Restor Dent Endod (2014)

Periapical radiograph of the left permanent mandibular second premolar six months after treatment.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4125589&req=5

Figure 3: Periapical radiograph of the left permanent mandibular second premolar six months after treatment.
Mentions: The root canal was irrigated with sterile saline solution and dried with sterile paper points under rubber dam isolation. Then, PRP was injected gently into the root canal to the level of cemento-enamel junction (CEJ) using an insulin syringe, and allowed to clot for 10 minutes. MTA (Pro-Root MTA, Dentsply Maillefer, Baillagues, Switzerland) was then placed into the root canal with a wet cotton pellet placed over. The cotton pellet was removed after 10 minutes. Glass ionomer cement was placed against the MTA, and adhesive (Excite DSC, Ivoclar Vivadent AG, Schaan, Liechtenstein) was applied according to the manufacturer's instructions. Finally, composite restoration was completed with Tetric Ceram (Ivoclar Vivadent AG) using the incremental technique, followed by occlusal adjustment (Figure 2). The patient was asymptomatic six months after the treatment. The radiographic presentation of the radiolucency was healed and the root continued to develop (Figure 3). At the 2-year recall, the root of the tooth was fully developed (Figure 4).

Bottom Line: This study describes the treatment of an immature permanent tooth with periapical lesion which was treated with regenerative approach using platelet rich plasma (PRP).The root canal of immature human permanent tooth with periapical lesion was gently debrided of necrotic tissue and disinfected with 2.5% NaOCl, and then medicated with triple antibiotic paste comprised of ciprofloxacin, metronidazole, and tetracycline.Our findings suggest that PRP can be used for the treatment of immature permanent teeth with periapical lesion, as part of a regenerative endodontic treatment procedure.

View Article: PubMed Central - PubMed

Affiliation: Department of Pediatric Dentistry, Center for Dental Sciences, Gulhane Medical Academy, Ankara, Turkey.

ABSTRACT
This study describes the treatment of an immature permanent tooth with periapical lesion which was treated with regenerative approach using platelet rich plasma (PRP). The root canal of immature human permanent tooth with periapical lesion was gently debrided of necrotic tissue and disinfected with 2.5% NaOCl, and then medicated with triple antibiotic paste comprised of ciprofloxacin, metronidazole, and tetracycline. When the tooth was asymptomatic, PRP and mineral trioxide aggregate (MTA) were placed into the root canal. Six months after PRP treatment, radiographical examination revealed resolution of the radiolucency and progressive thickening of the root wall and apical closure. Our findings suggest that PRP can be used for the treatment of immature permanent teeth with periapical lesion, as part of a regenerative endodontic treatment procedure.

No MeSH data available.


Related in: MedlinePlus