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The use of platelet rich plasma in the treatment of immature tooth with periapical lesion: a case report.

Güven Polat G, Yıldırım C, Akgün OM, Altun C, Dinçer D, Ozkan CK - Restor Dent Endod (2014)

Bottom Line: This study describes the treatment of an immature permanent tooth with periapical lesion which was treated with regenerative approach using platelet rich plasma (PRP).The root canal of immature human permanent tooth with periapical lesion was gently debrided of necrotic tissue and disinfected with 2.5% NaOCl, and then medicated with triple antibiotic paste comprised of ciprofloxacin, metronidazole, and tetracycline.Our findings suggest that PRP can be used for the treatment of immature permanent teeth with periapical lesion, as part of a regenerative endodontic treatment procedure.

View Article: PubMed Central - PubMed

Affiliation: Department of Pediatric Dentistry, Center for Dental Sciences, Gulhane Medical Academy, Ankara, Turkey.

ABSTRACT
This study describes the treatment of an immature permanent tooth with periapical lesion which was treated with regenerative approach using platelet rich plasma (PRP). The root canal of immature human permanent tooth with periapical lesion was gently debrided of necrotic tissue and disinfected with 2.5% NaOCl, and then medicated with triple antibiotic paste comprised of ciprofloxacin, metronidazole, and tetracycline. When the tooth was asymptomatic, PRP and mineral trioxide aggregate (MTA) were placed into the root canal. Six months after PRP treatment, radiographical examination revealed resolution of the radiolucency and progressive thickening of the root wall and apical closure. Our findings suggest that PRP can be used for the treatment of immature permanent teeth with periapical lesion, as part of a regenerative endodontic treatment procedure.

No MeSH data available.


Related in: MedlinePlus

Periapical radiograph of the left permanent mandibular second premolar before treatment.
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Figure 1: Periapical radiograph of the left permanent mandibular second premolar before treatment.

Mentions: 10-year-old female patient was referred to the Department of Pediatric Dentistry complaining of swelling of the left permanent mandibular second premolar. Radiographic examination of this tooth revealed an open apex associated with a large radiolucency (Figure 1). According to intraoral examination, the tooth had enamel hypoplasia and caries. A buccal sinus tract was present, which traced to the apex of the tooth. Negative responses to electric pulp test (EPT) and cold sensivity test were recorded. Response to percussion and palpation were within normal limits. It was decided that the PRP procedure was appropriate in this case because positive results can be obtained in a short time using PRP. The procedure was explained to the parents and informed consent was obtained. A treatment plan was formulated which included the use of PRP as an internal matrix and mineral trioxide aggregate (MTA) as an apical barrier. The treatment plan was explained to the parents, and a customized informed consent form was subsequently signed.


The use of platelet rich plasma in the treatment of immature tooth with periapical lesion: a case report.

Güven Polat G, Yıldırım C, Akgün OM, Altun C, Dinçer D, Ozkan CK - Restor Dent Endod (2014)

Periapical radiograph of the left permanent mandibular second premolar before treatment.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4125589&req=5

Figure 1: Periapical radiograph of the left permanent mandibular second premolar before treatment.
Mentions: 10-year-old female patient was referred to the Department of Pediatric Dentistry complaining of swelling of the left permanent mandibular second premolar. Radiographic examination of this tooth revealed an open apex associated with a large radiolucency (Figure 1). According to intraoral examination, the tooth had enamel hypoplasia and caries. A buccal sinus tract was present, which traced to the apex of the tooth. Negative responses to electric pulp test (EPT) and cold sensivity test were recorded. Response to percussion and palpation were within normal limits. It was decided that the PRP procedure was appropriate in this case because positive results can be obtained in a short time using PRP. The procedure was explained to the parents and informed consent was obtained. A treatment plan was formulated which included the use of PRP as an internal matrix and mineral trioxide aggregate (MTA) as an apical barrier. The treatment plan was explained to the parents, and a customized informed consent form was subsequently signed.

Bottom Line: This study describes the treatment of an immature permanent tooth with periapical lesion which was treated with regenerative approach using platelet rich plasma (PRP).The root canal of immature human permanent tooth with periapical lesion was gently debrided of necrotic tissue and disinfected with 2.5% NaOCl, and then medicated with triple antibiotic paste comprised of ciprofloxacin, metronidazole, and tetracycline.Our findings suggest that PRP can be used for the treatment of immature permanent teeth with periapical lesion, as part of a regenerative endodontic treatment procedure.

View Article: PubMed Central - PubMed

Affiliation: Department of Pediatric Dentistry, Center for Dental Sciences, Gulhane Medical Academy, Ankara, Turkey.

ABSTRACT
This study describes the treatment of an immature permanent tooth with periapical lesion which was treated with regenerative approach using platelet rich plasma (PRP). The root canal of immature human permanent tooth with periapical lesion was gently debrided of necrotic tissue and disinfected with 2.5% NaOCl, and then medicated with triple antibiotic paste comprised of ciprofloxacin, metronidazole, and tetracycline. When the tooth was asymptomatic, PRP and mineral trioxide aggregate (MTA) were placed into the root canal. Six months after PRP treatment, radiographical examination revealed resolution of the radiolucency and progressive thickening of the root wall and apical closure. Our findings suggest that PRP can be used for the treatment of immature permanent teeth with periapical lesion, as part of a regenerative endodontic treatment procedure.

No MeSH data available.


Related in: MedlinePlus