Plasma levels of S100B in preeclampsia and association with possible central nervous system effects.
Bottom Line: The purpose of this study was to compare levels of S100B in women with preeclampsia with levels in healthy pregnant control subjects and furthermore to analyze levels of S100B in relation to possible CNS effects.The main outcome measures were plasma levels of S100B and possible CNS effects.Levels of S100B were significantly higher among women with preeclampsia than among control subjects (0.12 µg/L vs. 0.07 µg/L; P < 0.001).
Affiliation: Department of Women's and Children's Health, Uppsala University, Uppsala, Sweden; Centre for Clinical Research, Dalarna, Sweden; email@example.com.Show MeSH
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Mentions: Levels of S100B in plasma for women with preeclampsia and healthy control subjects are presented as a boxplot in Figure 1. Women with preeclampsia had significantly higher median levels of S100B compared with control subjects (0.12 µg/L, 0.02–0.77 µg/L; vs. 0.07 µg/L, 0.02–0.31 µg/L; P < 0.001). Postpartum samples were available from some (n = 12) of the women with preeclampsia and the postpartum median levels were significantly higher when compared with samples collected before partus (n = 41) in that group of women (0.16 µg/L, 0.03–0.77 µg/L; vs. 0.11 µg/L, 0.02–0.33 µg/L; P < 0.05).
Affiliation: Department of Women's and Children's Health, Uppsala University, Uppsala, Sweden; Centre for Clinical Research, Dalarna, Sweden; firstname.lastname@example.org.