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Plasma levels of S100B in preeclampsia and association with possible central nervous system effects.

Bergman L, Akhter T, Wikström AK, Wikström J, Naessen T, Åkerud H - Am. J. Hypertens. (2014)

Bottom Line: The purpose of this study was to compare levels of S100B in women with preeclampsia with levels in healthy pregnant control subjects and furthermore to analyze levels of S100B in relation to possible CNS effects.The main outcome measures were plasma levels of S100B and possible CNS effects.Levels of S100B were significantly higher among women with preeclampsia than among control subjects (0.12 µg/L vs. 0.07 µg/L; P < 0.001).

View Article: PubMed Central - PubMed

Affiliation: Department of Women's and Children's Health, Uppsala University, Uppsala, Sweden; Centre for Clinical Research, Dalarna, Sweden; lina.bergman@kbh.uu.se.

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Related in: MedlinePlus

Boxplot showing levels of S100B among case patients and control subjects. The top and bottom of the box represent the third and first quartiles. The horizontal line within the box represents the median value. The bars on the sides of the box represent the highest and the lowest value. The circles represent extreme values >1.5 × interquartile range (IQR), and the asterisks represent extreme values >3 × IQR. P < 0.001.
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Figure 1: Boxplot showing levels of S100B among case patients and control subjects. The top and bottom of the box represent the third and first quartiles. The horizontal line within the box represents the median value. The bars on the sides of the box represent the highest and the lowest value. The circles represent extreme values >1.5 × interquartile range (IQR), and the asterisks represent extreme values >3 × IQR. P < 0.001.

Mentions: Levels of S100B in plasma for women with preeclampsia and healthy control subjects are presented as a boxplot in Figure 1. Women with preeclampsia had significantly higher median levels of S100B compared with control subjects (0.12 µg/L, 0.02–0.77 µg/L; vs. 0.07 µg/L, 0.02–0.31 µg/L; P < 0.001). Postpartum samples were available from some (n = 12) of the women with preeclampsia and the postpartum median levels were significantly higher when compared with samples collected before partus (n = 41) in that group of women (0.16 µg/L, 0.03–0.77 µg/L; vs. 0.11 µg/L, 0.02–0.33 µg/L; P < 0.05).


Plasma levels of S100B in preeclampsia and association with possible central nervous system effects.

Bergman L, Akhter T, Wikström AK, Wikström J, Naessen T, Åkerud H - Am. J. Hypertens. (2014)

Boxplot showing levels of S100B among case patients and control subjects. The top and bottom of the box represent the third and first quartiles. The horizontal line within the box represents the median value. The bars on the sides of the box represent the highest and the lowest value. The circles represent extreme values >1.5 × interquartile range (IQR), and the asterisks represent extreme values >3 × IQR. P < 0.001.
© Copyright Policy - creative-commons
Related In: Results  -  Collection

License 1 - License 2
Show All Figures
getmorefigures.php?uid=PMC4125339&req=5

Figure 1: Boxplot showing levels of S100B among case patients and control subjects. The top and bottom of the box represent the third and first quartiles. The horizontal line within the box represents the median value. The bars on the sides of the box represent the highest and the lowest value. The circles represent extreme values >1.5 × interquartile range (IQR), and the asterisks represent extreme values >3 × IQR. P < 0.001.
Mentions: Levels of S100B in plasma for women with preeclampsia and healthy control subjects are presented as a boxplot in Figure 1. Women with preeclampsia had significantly higher median levels of S100B compared with control subjects (0.12 µg/L, 0.02–0.77 µg/L; vs. 0.07 µg/L, 0.02–0.31 µg/L; P < 0.001). Postpartum samples were available from some (n = 12) of the women with preeclampsia and the postpartum median levels were significantly higher when compared with samples collected before partus (n = 41) in that group of women (0.16 µg/L, 0.03–0.77 µg/L; vs. 0.11 µg/L, 0.02–0.33 µg/L; P < 0.05).

Bottom Line: The purpose of this study was to compare levels of S100B in women with preeclampsia with levels in healthy pregnant control subjects and furthermore to analyze levels of S100B in relation to possible CNS effects.The main outcome measures were plasma levels of S100B and possible CNS effects.Levels of S100B were significantly higher among women with preeclampsia than among control subjects (0.12 µg/L vs. 0.07 µg/L; P < 0.001).

View Article: PubMed Central - PubMed

Affiliation: Department of Women's and Children's Health, Uppsala University, Uppsala, Sweden; Centre for Clinical Research, Dalarna, Sweden; lina.bergman@kbh.uu.se.

Show MeSH
Related in: MedlinePlus