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Efficacy of eye-movement desensitization and reprocessing for patients with posttraumatic-stress disorder: a meta-analysis of randomized controlled trials.

Chen YR, Hung KW, Tsai JC, Chu H, Chung MH, Chen SR, Liao YM, Ou KL, Chang YC, Chou KR - PLoS ONE (2014)

Bottom Line: We performed the first meta-analysis of clinical studies by investigating the effects of eye-movement desensitization and reprocessing (EMDR) therapy on the symptoms of posttraumatic stress disorder (PTSD), depression, anxiety, and subjective distress in PTSD patients treated during the past 2 decades.This study confirmed that EMDR therapy significantly reduces the symptoms of PTSD, depression, anxiety, and subjective distress in PTSD patients.The subgroup analysis indicated that a treatment duration of more than 60 min per session was a major contributing factor in the amelioration of anxiety and depression, and that a therapist with experience in conducting PTSD group therapy was a major contributing factor in the reduction of PTSD symptoms.

View Article: PubMed Central - PubMed

Affiliation: Graduate Institute of Nursing, College of Nursing, Taipei Medical University, Taipei, Taiwan, and Taoyuan Armed Forces General Hospital, Longtan, Taiwan.

ABSTRACT

Background: We performed the first meta-analysis of clinical studies by investigating the effects of eye-movement desensitization and reprocessing (EMDR) therapy on the symptoms of posttraumatic stress disorder (PTSD), depression, anxiety, and subjective distress in PTSD patients treated during the past 2 decades.

Methods: We performed a quantitative meta-analysis on the findings of 26 randomized controlled trials of EMDR therapy for PTSD published between 1991 and 2013, which were identified through the ISI Web of Science, Embase, Cochrane Library, MEDLINE, PubMed, Scopus, PsycINFO, and the Cumulative Index to Nursing and Allied Health Literature electronic databases, among which 22, 20, 16, and 11 of the studies assessed the effects of EMDR on the symptoms of PTSD, depression, anxiety, and subjective distress, respectively, as the primary clinical outcome.

Results: The meta-analysis revealed that the EMDR treatments significantly reduced the symptoms of PTSD (g = -0.662; 95% confidence interval (CI): -0.887 to -0.436), depression (g = -0.643; 95% CI: -0.864 to -0.422), anxiety (g = -0.640; 95% CI: -0.890 to -0.390), and subjective distress (g = -0.956; 95% CI: -1.388 to -0.525) in PTSD patients.

Conclusion: This study confirmed that EMDR therapy significantly reduces the symptoms of PTSD, depression, anxiety, and subjective distress in PTSD patients. The subgroup analysis indicated that a treatment duration of more than 60 min per session was a major contributing factor in the amelioration of anxiety and depression, and that a therapist with experience in conducting PTSD group therapy was a major contributing factor in the reduction of PTSD symptoms.

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Related in: MedlinePlus

Overall effect size of the reduction in the symptoms of depression in PTSD patients following EMDR therapy (n = 20 studies).
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pone-0103676-g003: Overall effect size of the reduction in the symptoms of depression in PTSD patients following EMDR therapy (n = 20 studies).

Mentions: Twenty studies that investigated depression as the primary outcome following EMDR therapy were included in our meta-analysis. The Hedges's g for the overall effect size was −0.643, and the 95% CI was −0.864 to −0.422 (Table 2, Figure 3). The effect sizes for sample collection were all negative, with the Hedges's g ranging from −0.076 to −1.995. These results suggested that the overall reduction in depression following EMDR therapy was significant, with a moderate effect size. Heterogeneity among the studies of depression was moderate (Q = 42.657, p = 0.001, I2 = 55.458). The funnel plot for these studies was approximately symmetrical, and the Egger's regression test revealed no publication bias (p = 0.74). The sensitivity analysis indicated that the removal of any one study did not affect the overall results.


Efficacy of eye-movement desensitization and reprocessing for patients with posttraumatic-stress disorder: a meta-analysis of randomized controlled trials.

Chen YR, Hung KW, Tsai JC, Chu H, Chung MH, Chen SR, Liao YM, Ou KL, Chang YC, Chou KR - PLoS ONE (2014)

Overall effect size of the reduction in the symptoms of depression in PTSD patients following EMDR therapy (n = 20 studies).
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4125321&req=5

pone-0103676-g003: Overall effect size of the reduction in the symptoms of depression in PTSD patients following EMDR therapy (n = 20 studies).
Mentions: Twenty studies that investigated depression as the primary outcome following EMDR therapy were included in our meta-analysis. The Hedges's g for the overall effect size was −0.643, and the 95% CI was −0.864 to −0.422 (Table 2, Figure 3). The effect sizes for sample collection were all negative, with the Hedges's g ranging from −0.076 to −1.995. These results suggested that the overall reduction in depression following EMDR therapy was significant, with a moderate effect size. Heterogeneity among the studies of depression was moderate (Q = 42.657, p = 0.001, I2 = 55.458). The funnel plot for these studies was approximately symmetrical, and the Egger's regression test revealed no publication bias (p = 0.74). The sensitivity analysis indicated that the removal of any one study did not affect the overall results.

Bottom Line: We performed the first meta-analysis of clinical studies by investigating the effects of eye-movement desensitization and reprocessing (EMDR) therapy on the symptoms of posttraumatic stress disorder (PTSD), depression, anxiety, and subjective distress in PTSD patients treated during the past 2 decades.This study confirmed that EMDR therapy significantly reduces the symptoms of PTSD, depression, anxiety, and subjective distress in PTSD patients.The subgroup analysis indicated that a treatment duration of more than 60 min per session was a major contributing factor in the amelioration of anxiety and depression, and that a therapist with experience in conducting PTSD group therapy was a major contributing factor in the reduction of PTSD symptoms.

View Article: PubMed Central - PubMed

Affiliation: Graduate Institute of Nursing, College of Nursing, Taipei Medical University, Taipei, Taiwan, and Taoyuan Armed Forces General Hospital, Longtan, Taiwan.

ABSTRACT

Background: We performed the first meta-analysis of clinical studies by investigating the effects of eye-movement desensitization and reprocessing (EMDR) therapy on the symptoms of posttraumatic stress disorder (PTSD), depression, anxiety, and subjective distress in PTSD patients treated during the past 2 decades.

Methods: We performed a quantitative meta-analysis on the findings of 26 randomized controlled trials of EMDR therapy for PTSD published between 1991 and 2013, which were identified through the ISI Web of Science, Embase, Cochrane Library, MEDLINE, PubMed, Scopus, PsycINFO, and the Cumulative Index to Nursing and Allied Health Literature electronic databases, among which 22, 20, 16, and 11 of the studies assessed the effects of EMDR on the symptoms of PTSD, depression, anxiety, and subjective distress, respectively, as the primary clinical outcome.

Results: The meta-analysis revealed that the EMDR treatments significantly reduced the symptoms of PTSD (g = -0.662; 95% confidence interval (CI): -0.887 to -0.436), depression (g = -0.643; 95% CI: -0.864 to -0.422), anxiety (g = -0.640; 95% CI: -0.890 to -0.390), and subjective distress (g = -0.956; 95% CI: -1.388 to -0.525) in PTSD patients.

Conclusion: This study confirmed that EMDR therapy significantly reduces the symptoms of PTSD, depression, anxiety, and subjective distress in PTSD patients. The subgroup analysis indicated that a treatment duration of more than 60 min per session was a major contributing factor in the amelioration of anxiety and depression, and that a therapist with experience in conducting PTSD group therapy was a major contributing factor in the reduction of PTSD symptoms.

Show MeSH
Related in: MedlinePlus