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Efficacy of eye-movement desensitization and reprocessing for patients with posttraumatic-stress disorder: a meta-analysis of randomized controlled trials.

Chen YR, Hung KW, Tsai JC, Chu H, Chung MH, Chen SR, Liao YM, Ou KL, Chang YC, Chou KR - PLoS ONE (2014)

Bottom Line: We performed the first meta-analysis of clinical studies by investigating the effects of eye-movement desensitization and reprocessing (EMDR) therapy on the symptoms of posttraumatic stress disorder (PTSD), depression, anxiety, and subjective distress in PTSD patients treated during the past 2 decades.This study confirmed that EMDR therapy significantly reduces the symptoms of PTSD, depression, anxiety, and subjective distress in PTSD patients.The subgroup analysis indicated that a treatment duration of more than 60 min per session was a major contributing factor in the amelioration of anxiety and depression, and that a therapist with experience in conducting PTSD group therapy was a major contributing factor in the reduction of PTSD symptoms.

View Article: PubMed Central - PubMed

Affiliation: Graduate Institute of Nursing, College of Nursing, Taipei Medical University, Taipei, Taiwan, and Taoyuan Armed Forces General Hospital, Longtan, Taiwan.

ABSTRACT

Background: We performed the first meta-analysis of clinical studies by investigating the effects of eye-movement desensitization and reprocessing (EMDR) therapy on the symptoms of posttraumatic stress disorder (PTSD), depression, anxiety, and subjective distress in PTSD patients treated during the past 2 decades.

Methods: We performed a quantitative meta-analysis on the findings of 26 randomized controlled trials of EMDR therapy for PTSD published between 1991 and 2013, which were identified through the ISI Web of Science, Embase, Cochrane Library, MEDLINE, PubMed, Scopus, PsycINFO, and the Cumulative Index to Nursing and Allied Health Literature electronic databases, among which 22, 20, 16, and 11 of the studies assessed the effects of EMDR on the symptoms of PTSD, depression, anxiety, and subjective distress, respectively, as the primary clinical outcome.

Results: The meta-analysis revealed that the EMDR treatments significantly reduced the symptoms of PTSD (g = -0.662; 95% confidence interval (CI): -0.887 to -0.436), depression (g = -0.643; 95% CI: -0.864 to -0.422), anxiety (g = -0.640; 95% CI: -0.890 to -0.390), and subjective distress (g = -0.956; 95% CI: -1.388 to -0.525) in PTSD patients.

Conclusion: This study confirmed that EMDR therapy significantly reduces the symptoms of PTSD, depression, anxiety, and subjective distress in PTSD patients. The subgroup analysis indicated that a treatment duration of more than 60 min per session was a major contributing factor in the amelioration of anxiety and depression, and that a therapist with experience in conducting PTSD group therapy was a major contributing factor in the reduction of PTSD symptoms.

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pone-0103676-g001: PRISMA 2009 flow diagram.

Mentions: The inclusion criteria for the current study were based on those used in similar studies and our research objectives. Previous studies were selected for the meta-analysis based on the following inclusion criteria: (1) published between January 1991 and December 2013; (2) included PTSD patients treated with EMDR; (3) met the requirements of an RCT established by the Cochrane Collaboration [17]; (4) EMDR was administered by trained professionals, including physicians, nurses, or psychotherapists; (5) control patients received other treatment or no treatment; and (6) the assessment of clinical outcomes included an adequate statistical analysis of the effect size, such as the mean, standard deviation, mean difference, sample size, t value, F value, odds ratio (OR), or P value. Duplicate publications, qualitative studies, quasi-experimental studies, and single-subject or single-group experimental studies were excluded. The RCT selection process is depicted in Figure 1.


Efficacy of eye-movement desensitization and reprocessing for patients with posttraumatic-stress disorder: a meta-analysis of randomized controlled trials.

Chen YR, Hung KW, Tsai JC, Chu H, Chung MH, Chen SR, Liao YM, Ou KL, Chang YC, Chou KR - PLoS ONE (2014)

PRISMA 2009 flow diagram.
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4125321&req=5

pone-0103676-g001: PRISMA 2009 flow diagram.
Mentions: The inclusion criteria for the current study were based on those used in similar studies and our research objectives. Previous studies were selected for the meta-analysis based on the following inclusion criteria: (1) published between January 1991 and December 2013; (2) included PTSD patients treated with EMDR; (3) met the requirements of an RCT established by the Cochrane Collaboration [17]; (4) EMDR was administered by trained professionals, including physicians, nurses, or psychotherapists; (5) control patients received other treatment or no treatment; and (6) the assessment of clinical outcomes included an adequate statistical analysis of the effect size, such as the mean, standard deviation, mean difference, sample size, t value, F value, odds ratio (OR), or P value. Duplicate publications, qualitative studies, quasi-experimental studies, and single-subject or single-group experimental studies were excluded. The RCT selection process is depicted in Figure 1.

Bottom Line: We performed the first meta-analysis of clinical studies by investigating the effects of eye-movement desensitization and reprocessing (EMDR) therapy on the symptoms of posttraumatic stress disorder (PTSD), depression, anxiety, and subjective distress in PTSD patients treated during the past 2 decades.This study confirmed that EMDR therapy significantly reduces the symptoms of PTSD, depression, anxiety, and subjective distress in PTSD patients.The subgroup analysis indicated that a treatment duration of more than 60 min per session was a major contributing factor in the amelioration of anxiety and depression, and that a therapist with experience in conducting PTSD group therapy was a major contributing factor in the reduction of PTSD symptoms.

View Article: PubMed Central - PubMed

Affiliation: Graduate Institute of Nursing, College of Nursing, Taipei Medical University, Taipei, Taiwan, and Taoyuan Armed Forces General Hospital, Longtan, Taiwan.

ABSTRACT

Background: We performed the first meta-analysis of clinical studies by investigating the effects of eye-movement desensitization and reprocessing (EMDR) therapy on the symptoms of posttraumatic stress disorder (PTSD), depression, anxiety, and subjective distress in PTSD patients treated during the past 2 decades.

Methods: We performed a quantitative meta-analysis on the findings of 26 randomized controlled trials of EMDR therapy for PTSD published between 1991 and 2013, which were identified through the ISI Web of Science, Embase, Cochrane Library, MEDLINE, PubMed, Scopus, PsycINFO, and the Cumulative Index to Nursing and Allied Health Literature electronic databases, among which 22, 20, 16, and 11 of the studies assessed the effects of EMDR on the symptoms of PTSD, depression, anxiety, and subjective distress, respectively, as the primary clinical outcome.

Results: The meta-analysis revealed that the EMDR treatments significantly reduced the symptoms of PTSD (g = -0.662; 95% confidence interval (CI): -0.887 to -0.436), depression (g = -0.643; 95% CI: -0.864 to -0.422), anxiety (g = -0.640; 95% CI: -0.890 to -0.390), and subjective distress (g = -0.956; 95% CI: -1.388 to -0.525) in PTSD patients.

Conclusion: This study confirmed that EMDR therapy significantly reduces the symptoms of PTSD, depression, anxiety, and subjective distress in PTSD patients. The subgroup analysis indicated that a treatment duration of more than 60 min per session was a major contributing factor in the amelioration of anxiety and depression, and that a therapist with experience in conducting PTSD group therapy was a major contributing factor in the reduction of PTSD symptoms.

Show MeSH
Related in: MedlinePlus