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Autologous haematopoietic stem cell transplantation following high-dose chemotherapy for non-rhabdomyosarcoma soft tissue sarcomas: a Cochrane systematic review*.

Peinemann F, Labeit AM - BMJ Open (2014)

Bottom Line: The planned and measured primary outcomes were overall survival and treatment-related mortality.The planned and measured secondary outcomes were progression-free survival, grade 3-4 non-haematological toxicity and secondary neoplasia.Treatment-related mortality was reported in 5.1% (15 of 294) transplanted patients.

View Article: PubMed Central - PubMed

Affiliation: Children's Hospital, University of Cologne, Cologne, Germany.

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Related in: MedlinePlus

Literature search and study flow.
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BMJOPEN2014005033F1: Literature search and study flow.

Mentions: Figure 1 shows the literature search and study flow. We retrieved 1035 records and evaluated 260 full text papers in detail. We included 62 studies with 294 transplanted patients, 1 RCT with 38 transplanted and 45 non-transplanted patients,21 6 single-arm studies reporting aggregate case series data,22–27 and 55 single-arm studies with individual data. In online registries, we identified 6 studies with a still pending completion and we did not find additional studies in the update search.


Autologous haematopoietic stem cell transplantation following high-dose chemotherapy for non-rhabdomyosarcoma soft tissue sarcomas: a Cochrane systematic review*.

Peinemann F, Labeit AM - BMJ Open (2014)

Literature search and study flow.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4120440&req=5

BMJOPEN2014005033F1: Literature search and study flow.
Mentions: Figure 1 shows the literature search and study flow. We retrieved 1035 records and evaluated 260 full text papers in detail. We included 62 studies with 294 transplanted patients, 1 RCT with 38 transplanted and 45 non-transplanted patients,21 6 single-arm studies reporting aggregate case series data,22–27 and 55 single-arm studies with individual data. In online registries, we identified 6 studies with a still pending completion and we did not find additional studies in the update search.

Bottom Line: The planned and measured primary outcomes were overall survival and treatment-related mortality.The planned and measured secondary outcomes were progression-free survival, grade 3-4 non-haematological toxicity and secondary neoplasia.Treatment-related mortality was reported in 5.1% (15 of 294) transplanted patients.

View Article: PubMed Central - PubMed

Affiliation: Children's Hospital, University of Cologne, Cologne, Germany.

Show MeSH
Related in: MedlinePlus