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Recurrent benign adrenal pheochromocytomas associated with hemihypertrophy.

Pikilidou M, Yavropoulou M, Katsounaros M - Endocrinol Diabetes Metab Case Rep (2014)

Bottom Line: We report a case of a female with hemihypertrophy, who developed five recurrences of pheochromocytomas until the age of 35.Timely follow-up of the patient's blood pressure assisted in early diagnosis and treatment of recurrent tumors.Recurrent benign pheochromocytomas should raise suspicion of a genetic syndrome.A pheochromocytoma at a young age has a high propensity to recur and strict follow-up is mandatory.

View Article: PubMed Central - PubMed

Affiliation: Hypertension Excellence Center, First Department of Internal Medicine , AHEPA University Hospital , Thessaloniki , Greece ; Second Department of Internal Medicine , Papanikolaou General Hospital , Thessaloniki , Greece.

ABSTRACT

Unlabelled: We report a case of a female with hemihypertrophy, who developed five recurrences of pheochromocytomas until the age of 35. Timely follow-up of the patient's blood pressure assisted in early diagnosis and treatment of recurrent tumors.

Learning points: Recurrent benign pheochromocytomas should raise suspicion of a genetic syndrome.A pheochromocytoma at a young age has a high propensity to recur and strict follow-up is mandatory.

No MeSH data available.


Related in: MedlinePlus

MRI of the abdomen showing (a) a heterogeneous mass in the anatomic region of the left adrenal gland. (b) Imaging after resection of the tumor.
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fig2: MRI of the abdomen showing (a) a heterogeneous mass in the anatomic region of the left adrenal gland. (b) Imaging after resection of the tumor.

Mentions: During her clinical examination in our center, the patient had right ipsilateral hemihypertrophy, significant leg length discrepancy (left leg, 85 cm and right leg, 92 cm), and abdominal wall defects (Fig. 1). At the time of admission, her blood pressure was 270/140 mmHg with a heart rate of 146 b.p.m. (sinus tachycardia). Remarkable findings from the laboratory examinations included significantly elevated 24 h urine 3-methoxy-4-hydroxymandelic acid, and fractionated metanephrine levels and increased plasma metanephrine levels (Table 1). A new pheochromocytoma was then clinically and biochemically suspected and magnetic resonance imaging (MRI) scan of the abdomen identified a tumor on the anatomic region of the left adrenal gland (Fig. 2a).


Recurrent benign adrenal pheochromocytomas associated with hemihypertrophy.

Pikilidou M, Yavropoulou M, Katsounaros M - Endocrinol Diabetes Metab Case Rep (2014)

MRI of the abdomen showing (a) a heterogeneous mass in the anatomic region of the left adrenal gland. (b) Imaging after resection of the tumor.
© Copyright Policy - license
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4120361&req=5

fig2: MRI of the abdomen showing (a) a heterogeneous mass in the anatomic region of the left adrenal gland. (b) Imaging after resection of the tumor.
Mentions: During her clinical examination in our center, the patient had right ipsilateral hemihypertrophy, significant leg length discrepancy (left leg, 85 cm and right leg, 92 cm), and abdominal wall defects (Fig. 1). At the time of admission, her blood pressure was 270/140 mmHg with a heart rate of 146 b.p.m. (sinus tachycardia). Remarkable findings from the laboratory examinations included significantly elevated 24 h urine 3-methoxy-4-hydroxymandelic acid, and fractionated metanephrine levels and increased plasma metanephrine levels (Table 1). A new pheochromocytoma was then clinically and biochemically suspected and magnetic resonance imaging (MRI) scan of the abdomen identified a tumor on the anatomic region of the left adrenal gland (Fig. 2a).

Bottom Line: We report a case of a female with hemihypertrophy, who developed five recurrences of pheochromocytomas until the age of 35.Timely follow-up of the patient's blood pressure assisted in early diagnosis and treatment of recurrent tumors.Recurrent benign pheochromocytomas should raise suspicion of a genetic syndrome.A pheochromocytoma at a young age has a high propensity to recur and strict follow-up is mandatory.

View Article: PubMed Central - PubMed

Affiliation: Hypertension Excellence Center, First Department of Internal Medicine , AHEPA University Hospital , Thessaloniki , Greece ; Second Department of Internal Medicine , Papanikolaou General Hospital , Thessaloniki , Greece.

ABSTRACT

Unlabelled: We report a case of a female with hemihypertrophy, who developed five recurrences of pheochromocytomas until the age of 35. Timely follow-up of the patient's blood pressure assisted in early diagnosis and treatment of recurrent tumors.

Learning points: Recurrent benign pheochromocytomas should raise suspicion of a genetic syndrome.A pheochromocytoma at a young age has a high propensity to recur and strict follow-up is mandatory.

No MeSH data available.


Related in: MedlinePlus