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Higher order aberrations of the corneal surface after laser subepithelial keratomileusis.

Jung HH, Ji YS, Oh HJ, Yoon KC - Korean J Ophthalmol (2014)

Bottom Line: In the dry eye group, total HOA RMS, coma and trefoil significantly increased except for SA at 10 seconds after blinking compared with those measured immediately after blinking.In addition, the changes of total HOA RMS, coma and trefoil were negatively correlated with tear film break-up time (R = -0.420, -0.473 and -0.439, respectively), but positively correlated with OSDI score (R = 0.433, 0.499 and 0.532, respectively).The tear film instability in the dry eye can be associated with more deterioration of the optical quality after LASEK, due to more significant increase of total HOA RMS, coma and trefoil.

View Article: PubMed Central - PubMed

Affiliation: Department of Ophthalmology and Research Institute of Medical Sciences, Chonnam National University Hospital, Chonnam National University Medical School, Gwangju, Korea.

ABSTRACT

Purpose: To evaluate the changes of higher order aberrations (HOAs) before and after laser subepithelial keratomileusis (LASEK) and to analyze the influence of tear film instability on HOAs of the corneal surface after LASEK.

Methods: In this cross-sectional study, 31 patients who underwent LASEK were divided into dry eye (16 patients, 32 eyes) and non-dry eye groups (15 patients, 30 eyes). Uncorrected distance visual acuity, spherical equivalent refraction, ablation depth, tear film parameters and Ocular Surface Disease Index (OSDI) questionnaire scores were evaluated in both groups. Total HOA root mean square (RMS), third-order coma, third-order trefoil and fourth-order spherical aberration (SA) of the corneal surface immediately and at 10 seconds after blinking were measured before and after surgery.

Results: The total HOA RMS, coma, trefoil and SA significantly increased after LASEK compared with preoperative values in both groups. In the dry eye group, total HOA RMS, coma and trefoil significantly increased except for SA at 10 seconds after blinking compared with those measured immediately after blinking. In addition, the changes of total HOA RMS, coma and trefoil were negatively correlated with tear film break-up time (R = -0.420, -0.473 and -0.439, respectively), but positively correlated with OSDI score (R = 0.433, 0.499 and 0.532, respectively). In the non-dry eye group, there were no significant differences between HOAs measured at 10 seconds after blinking and those measured immediately after blinking.

Conclusions: The HOAs including coma, trefoil and SA significantly increased after LASEK. The tear film instability in the dry eye can be associated with more deterioration of the optical quality after LASEK, due to more significant increase of total HOA RMS, coma and trefoil.

No MeSH data available.


Related in: MedlinePlus

Changes of total higher order aberration root mean square (A), coma (B), trefoil (C) and spherical aberration (D) between values measured immediately after blinking and those measured at 10 seconds after blinking in the dry eye and the non-dry eye groups. *p < 0.05 (comparison of values measured immediately after blinking and those measured at 10 seconds after blinking).
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Figure 1: Changes of total higher order aberration root mean square (A), coma (B), trefoil (C) and spherical aberration (D) between values measured immediately after blinking and those measured at 10 seconds after blinking in the dry eye and the non-dry eye groups. *p < 0.05 (comparison of values measured immediately after blinking and those measured at 10 seconds after blinking).

Mentions: When comparing the dry eye and non-dry eye groups, there were no statistically significant differences in all values measured immediately after blinking before and after LASEK (Tables 2 and 3). However, at 10 seconds after blinking, the dry eye group had significantly higher total HOA RMS (p = 0.01), coma (p = 0.03), and trefoil (p = 0.04) than the non-dry eye group. In the dry eye group, total HOA RMS, coma, and trefoil significantly increased at 10 seconds after blinking compared with those measured immediately after blinking (p < 0.01, p = 0.03, and p = 0.04, respectively), whereas there was no significant difference in SA value (p = 0.62). In the non-dry eye group, there were no statistically significant differences in all HOA parameters (Table 3 and Fig. 1). The mean pupil sizes measured immediately after blinking and at 10 seconds after blinking didn't show significant differences in either group.


Higher order aberrations of the corneal surface after laser subepithelial keratomileusis.

Jung HH, Ji YS, Oh HJ, Yoon KC - Korean J Ophthalmol (2014)

Changes of total higher order aberration root mean square (A), coma (B), trefoil (C) and spherical aberration (D) between values measured immediately after blinking and those measured at 10 seconds after blinking in the dry eye and the non-dry eye groups. *p < 0.05 (comparison of values measured immediately after blinking and those measured at 10 seconds after blinking).
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4120348&req=5

Figure 1: Changes of total higher order aberration root mean square (A), coma (B), trefoil (C) and spherical aberration (D) between values measured immediately after blinking and those measured at 10 seconds after blinking in the dry eye and the non-dry eye groups. *p < 0.05 (comparison of values measured immediately after blinking and those measured at 10 seconds after blinking).
Mentions: When comparing the dry eye and non-dry eye groups, there were no statistically significant differences in all values measured immediately after blinking before and after LASEK (Tables 2 and 3). However, at 10 seconds after blinking, the dry eye group had significantly higher total HOA RMS (p = 0.01), coma (p = 0.03), and trefoil (p = 0.04) than the non-dry eye group. In the dry eye group, total HOA RMS, coma, and trefoil significantly increased at 10 seconds after blinking compared with those measured immediately after blinking (p < 0.01, p = 0.03, and p = 0.04, respectively), whereas there was no significant difference in SA value (p = 0.62). In the non-dry eye group, there were no statistically significant differences in all HOA parameters (Table 3 and Fig. 1). The mean pupil sizes measured immediately after blinking and at 10 seconds after blinking didn't show significant differences in either group.

Bottom Line: In the dry eye group, total HOA RMS, coma and trefoil significantly increased except for SA at 10 seconds after blinking compared with those measured immediately after blinking.In addition, the changes of total HOA RMS, coma and trefoil were negatively correlated with tear film break-up time (R = -0.420, -0.473 and -0.439, respectively), but positively correlated with OSDI score (R = 0.433, 0.499 and 0.532, respectively).The tear film instability in the dry eye can be associated with more deterioration of the optical quality after LASEK, due to more significant increase of total HOA RMS, coma and trefoil.

View Article: PubMed Central - PubMed

Affiliation: Department of Ophthalmology and Research Institute of Medical Sciences, Chonnam National University Hospital, Chonnam National University Medical School, Gwangju, Korea.

ABSTRACT

Purpose: To evaluate the changes of higher order aberrations (HOAs) before and after laser subepithelial keratomileusis (LASEK) and to analyze the influence of tear film instability on HOAs of the corneal surface after LASEK.

Methods: In this cross-sectional study, 31 patients who underwent LASEK were divided into dry eye (16 patients, 32 eyes) and non-dry eye groups (15 patients, 30 eyes). Uncorrected distance visual acuity, spherical equivalent refraction, ablation depth, tear film parameters and Ocular Surface Disease Index (OSDI) questionnaire scores were evaluated in both groups. Total HOA root mean square (RMS), third-order coma, third-order trefoil and fourth-order spherical aberration (SA) of the corneal surface immediately and at 10 seconds after blinking were measured before and after surgery.

Results: The total HOA RMS, coma, trefoil and SA significantly increased after LASEK compared with preoperative values in both groups. In the dry eye group, total HOA RMS, coma and trefoil significantly increased except for SA at 10 seconds after blinking compared with those measured immediately after blinking. In addition, the changes of total HOA RMS, coma and trefoil were negatively correlated with tear film break-up time (R = -0.420, -0.473 and -0.439, respectively), but positively correlated with OSDI score (R = 0.433, 0.499 and 0.532, respectively). In the non-dry eye group, there were no significant differences between HOAs measured at 10 seconds after blinking and those measured immediately after blinking.

Conclusions: The HOAs including coma, trefoil and SA significantly increased after LASEK. The tear film instability in the dry eye can be associated with more deterioration of the optical quality after LASEK, due to more significant increase of total HOA RMS, coma and trefoil.

No MeSH data available.


Related in: MedlinePlus