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Validation of chronic obstructive pulmonary disease recording in the Clinical Practice Research Datalink (CPRD-GOLD).

Quint JK, Müllerova H, DiSantostefano RL, Forbes H, Eaton S, Hurst JR, Davis K, Smeeth L - BMJ Open (2014)

Bottom Line: We assessed the accuracy of different approaches using the Clinical Practice Research Datalink, a UK electronic health record database. 951 participants registered with a CPRD practice in the UK between 1 January 2004 and 31 December 2012.Using a diagnostic code alone, the PPV was 86.5% (77.5-92.3%) while requiring a diagnosis plus spirometry plus specific medication; the PPV was slightly higher at 89.4% (80.7-94.5%) but reduced case numbers by 10%.Algorithms without specific diagnostic codes had low PPVs (range 12.2-44.4%).

View Article: PubMed Central - PubMed

Affiliation: Department of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK.

No MeSH data available.


Related in: MedlinePlus

Study population (COPD, chronic obstructive pulmonary disease; GP, general practitioner).
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BMJOPEN2014005540F1: Study population (COPD, chronic obstructive pulmonary disease; GP, general practitioner).

Mentions: Nine hundred and fifty-one questionnaires were sent to GPs (see figure 1 for patient selection). Of those, 738 (77.6%) were returned, 704 (74.0%) met quality control standards and were not duplicates and 696 (73.2%) could be included in the final analysis (8 had ‘uncertain’ COPD diagnosis and no supporting documentation and were therefore excluded).


Validation of chronic obstructive pulmonary disease recording in the Clinical Practice Research Datalink (CPRD-GOLD).

Quint JK, Müllerova H, DiSantostefano RL, Forbes H, Eaton S, Hurst JR, Davis K, Smeeth L - BMJ Open (2014)

Study population (COPD, chronic obstructive pulmonary disease; GP, general practitioner).
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4120321&req=5

BMJOPEN2014005540F1: Study population (COPD, chronic obstructive pulmonary disease; GP, general practitioner).
Mentions: Nine hundred and fifty-one questionnaires were sent to GPs (see figure 1 for patient selection). Of those, 738 (77.6%) were returned, 704 (74.0%) met quality control standards and were not duplicates and 696 (73.2%) could be included in the final analysis (8 had ‘uncertain’ COPD diagnosis and no supporting documentation and were therefore excluded).

Bottom Line: We assessed the accuracy of different approaches using the Clinical Practice Research Datalink, a UK electronic health record database. 951 participants registered with a CPRD practice in the UK between 1 January 2004 and 31 December 2012.Using a diagnostic code alone, the PPV was 86.5% (77.5-92.3%) while requiring a diagnosis plus spirometry plus specific medication; the PPV was slightly higher at 89.4% (80.7-94.5%) but reduced case numbers by 10%.Algorithms without specific diagnostic codes had low PPVs (range 12.2-44.4%).

View Article: PubMed Central - PubMed

Affiliation: Department of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK.

No MeSH data available.


Related in: MedlinePlus