Limits...
Ischaemia-related cell damage in extracorporeal preserved tissue - new findings with a novel perfusion model.

Taeger CD, Müller-Seubert W, Horch RE, Präbst K, Münch F, Geppert CI, Birkholz T, Dragu A - J. Cell. Mol. Med. (2014)

Bottom Line: Expression of Caspase-3 after 60 min. was reduced in all groups compared to the control group.Oxygenation leads to higher oxygen levels at the venous branch compared to groups without oxygenation.Complete depletion of oxygen at the venous branch can be prevented by oxygenation of the perfusate with ambient air.

View Article: PubMed Central - PubMed

Affiliation: Department of Plastic and Hand Surgery, Friedrich-Alexander-University of Erlangen-Nürnberg, Erlangen, Germany.

Show MeSH

Related in: MedlinePlus

Caspase-3 immunohistochemistry, percentage of positive cells after 60 min. of treatment, * statistically significant difference to the baseline.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
getmorefigures.php?uid=PMC4119394&req=5

fig05: Caspase-3 immunohistochemistry, percentage of positive cells after 60 min. of treatment, * statistically significant difference to the baseline.

Mentions: As shown in Figure 5, singular flush with the cardioplegic solution (group III) prevents a statistically significant increase in the expression of Caspase-3 during the different time-points 15, 30 and 60 min. compared to the baseline. Similar results have been found in the group that was treated with perfusion and oxygenation with the cardioplegic solution (group V).


Ischaemia-related cell damage in extracorporeal preserved tissue - new findings with a novel perfusion model.

Taeger CD, Müller-Seubert W, Horch RE, Präbst K, Münch F, Geppert CI, Birkholz T, Dragu A - J. Cell. Mol. Med. (2014)

Caspase-3 immunohistochemistry, percentage of positive cells after 60 min. of treatment, * statistically significant difference to the baseline.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4119394&req=5

fig05: Caspase-3 immunohistochemistry, percentage of positive cells after 60 min. of treatment, * statistically significant difference to the baseline.
Mentions: As shown in Figure 5, singular flush with the cardioplegic solution (group III) prevents a statistically significant increase in the expression of Caspase-3 during the different time-points 15, 30 and 60 min. compared to the baseline. Similar results have been found in the group that was treated with perfusion and oxygenation with the cardioplegic solution (group V).

Bottom Line: Expression of Caspase-3 after 60 min. was reduced in all groups compared to the control group.Oxygenation leads to higher oxygen levels at the venous branch compared to groups without oxygenation.Complete depletion of oxygen at the venous branch can be prevented by oxygenation of the perfusate with ambient air.

View Article: PubMed Central - PubMed

Affiliation: Department of Plastic and Hand Surgery, Friedrich-Alexander-University of Erlangen-Nürnberg, Erlangen, Germany.

Show MeSH
Related in: MedlinePlus