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Ischaemia-related cell damage in extracorporeal preserved tissue - new findings with a novel perfusion model.

Taeger CD, Müller-Seubert W, Horch RE, Präbst K, Münch F, Geppert CI, Birkholz T, Dragu A - J. Cell. Mol. Med. (2014)

Bottom Line: Expression of Caspase-3 after 60 min. was reduced in all groups compared to the control group.Oxygenation leads to higher oxygen levels at the venous branch compared to groups without oxygenation.Complete depletion of oxygen at the venous branch can be prevented by oxygenation of the perfusate with ambient air.

View Article: PubMed Central - PubMed

Affiliation: Department of Plastic and Hand Surgery, Friedrich-Alexander-University of Erlangen-Nürnberg, Erlangen, Germany.

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Related in: MedlinePlus

HIF-1-α staining 60 min. (control group), 200-fold magnification.
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fig11: HIF-1-α staining 60 min. (control group), 200-fold magnification.


Ischaemia-related cell damage in extracorporeal preserved tissue - new findings with a novel perfusion model.

Taeger CD, Müller-Seubert W, Horch RE, Präbst K, Münch F, Geppert CI, Birkholz T, Dragu A - J. Cell. Mol. Med. (2014)

HIF-1-α staining 60 min. (control group), 200-fold magnification.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4119394&req=5

fig11: HIF-1-α staining 60 min. (control group), 200-fold magnification.
Bottom Line: Expression of Caspase-3 after 60 min. was reduced in all groups compared to the control group.Oxygenation leads to higher oxygen levels at the venous branch compared to groups without oxygenation.Complete depletion of oxygen at the venous branch can be prevented by oxygenation of the perfusate with ambient air.

View Article: PubMed Central - PubMed

Affiliation: Department of Plastic and Hand Surgery, Friedrich-Alexander-University of Erlangen-Nürnberg, Erlangen, Germany.

Show MeSH
Related in: MedlinePlus