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Life in Science: Abraham Eisenstark.

Eisenstark A - Bacteriophage (2014)

View Article: PubMed Central - PubMed

Affiliation: Cancer Research Center, Columbia, Missouri; Byler Distinguished Professor (Emeritus), University of Missouri; Thomas Jefferson Professor, Univerity of Missouri; Columbia, MO USA.

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At the University of Illinois, there were exciting seminars and evening discussions with visiting molecular genetic giants (Delbrück, Hershey, Sonnenborn, etc)... A particularly inspiring phage research mentor was Edouard Kellenberger... He, his wife Grete Kellenberger and Nobelist Werner Arber were guest professors at Kansas State U during 1965–1966... Edouard and I shared the mentorship of PhD candidate Sam To, resulting in the publication of a paper discussing the disassembly of T-even bacteriophage into structural sements and subunits... Currently, via phage P22 transduction, we have rid Salmonella typhimurium LT2 of pathogenic genes, and inserted tumor-seeking genes... The genetically engineered strain reduces prostate tumors in mice, and we are continuing to use the phage-engineered Sallmonella in dogs with prostate cancers... While my passion for phage studies has received constant stimulations from mentors, a great joy has been to mentor numerous students at many levels of personal mentorship as well as in the classroom... Among future issues, I expect to learn of newly discovered bacteriophage from weird places (sea bottoms, deep into the center of the earth, and perhaps from bodies high in the sky), of phage that unravel more of the mysteries of nature, of phage that destroy disease agents, and of phage (via phage display technology) that serve as basic biochemical and even industrial tools... I look forward to seeing pictures of phage fine structures, learning of their unique functions, and perhaps of phage origins and evolutionary development from the beginning of world history... My enthusiasm for phage experiments may be explained by a statement by Linus Pauling who said his great joy was to see the results of an experiment and to know that he, and no one else in the world, then knew what he observed... Eureka!! For me, of course, other investigators can then read these results when they are published in a high impact journal, such as Bacteriophage.

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Abraham Eisenstark, Research Director, Cancer Research Center, Columbia, Missouri; Byler Distinguished Professor (Emeritus), University of Missouri; Thomas Jefferson Professor, Univerity of Missouri; Columbia, MO USA
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Fa: Abraham Eisenstark, Research Director, Cancer Research Center, Columbia, Missouri; Byler Distinguished Professor (Emeritus), University of Missouri; Thomas Jefferson Professor, Univerity of Missouri; Columbia, MO USA


Life in Science: Abraham Eisenstark.

Eisenstark A - Bacteriophage (2014)

Abraham Eisenstark, Research Director, Cancer Research Center, Columbia, Missouri; Byler Distinguished Professor (Emeritus), University of Missouri; Thomas Jefferson Professor, Univerity of Missouri; Columbia, MO USA
© Copyright Policy - open-access
Related In: Results  -  Collection

License
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getmorefigures.php?uid=PMC4116385&req=5

Fa: Abraham Eisenstark, Research Director, Cancer Research Center, Columbia, Missouri; Byler Distinguished Professor (Emeritus), University of Missouri; Thomas Jefferson Professor, Univerity of Missouri; Columbia, MO USA

View Article: PubMed Central - PubMed

Affiliation: Cancer Research Center, Columbia, Missouri; Byler Distinguished Professor (Emeritus), University of Missouri; Thomas Jefferson Professor, Univerity of Missouri; Columbia, MO USA.

AUTOMATICALLY GENERATED EXCERPT
Please rate it.

At the University of Illinois, there were exciting seminars and evening discussions with visiting molecular genetic giants (Delbrück, Hershey, Sonnenborn, etc)... A particularly inspiring phage research mentor was Edouard Kellenberger... He, his wife Grete Kellenberger and Nobelist Werner Arber were guest professors at Kansas State U during 1965–1966... Edouard and I shared the mentorship of PhD candidate Sam To, resulting in the publication of a paper discussing the disassembly of T-even bacteriophage into structural sements and subunits... Currently, via phage P22 transduction, we have rid Salmonella typhimurium LT2 of pathogenic genes, and inserted tumor-seeking genes... The genetically engineered strain reduces prostate tumors in mice, and we are continuing to use the phage-engineered Sallmonella in dogs with prostate cancers... While my passion for phage studies has received constant stimulations from mentors, a great joy has been to mentor numerous students at many levels of personal mentorship as well as in the classroom... Among future issues, I expect to learn of newly discovered bacteriophage from weird places (sea bottoms, deep into the center of the earth, and perhaps from bodies high in the sky), of phage that unravel more of the mysteries of nature, of phage that destroy disease agents, and of phage (via phage display technology) that serve as basic biochemical and even industrial tools... I look forward to seeing pictures of phage fine structures, learning of their unique functions, and perhaps of phage origins and evolutionary development from the beginning of world history... My enthusiasm for phage experiments may be explained by a statement by Linus Pauling who said his great joy was to see the results of an experiment and to know that he, and no one else in the world, then knew what he observed... Eureka!! For me, of course, other investigators can then read these results when they are published in a high impact journal, such as Bacteriophage.

No MeSH data available.


Related in: MedlinePlus