Limits...
Primary adrenal nodular lymphocyte-predominant Hodgkin lymphoma: A case report and review of the literature.

Wang J, Ma J, Hu C, Li D, She X - Oncol Lett (2014)

Bottom Line: The patient was without specific clinical signs and the definitive diagnosis was achieved by histological study.Given the rarity of this disease, there are limited experiences with regard to its diagnosis and treatment.This study is useful for the differential diagnosis and treatment of adrenal masses.

View Article: PubMed Central - PubMed

Affiliation: Department of Oncology, The Second Xiangya Hospital of Central South University, Changsha, Hunan 410011, P.R. China.

ABSTRACT
Nodular lymphocyte-predominant Hodgkin lymphoma (NLPHL) is a subtype of Hodgkin lymphoma (HL), and is a rare disease manifestation in the adrenal gland, which is difficult to be diagnosed and treated. In the present study, we report a case of primary adrenal NLPHL in a 36-year-old male patient. The patient was without specific clinical signs and the definitive diagnosis was achieved by histological study. The patient underwent a laparoscopic left adrenalectomy and chemotherapy regimen of doxorubicin, bleomycin, vinblastine and dacarbazine (ABVD). There is no standard treatment for adrenal NLPHL and therefore, treatment is based on that for other types of NLPHL, which includes radiotherapy and ABVD chemotherapy. Given the rarity of this disease, there are limited experiences with regard to its diagnosis and treatment. This study is useful for the differential diagnosis and treatment of adrenal masses.

No MeSH data available.


Related in: MedlinePlus

Abdominal computed tomography of the patient with primary adrenal nodular lymphocyte-predominant Hodgkin lymphoma. A soft tissue mass was observed in the left adrenal gland (arrow), measuring 4.5×5.5 cm, with a less uniform density and clear borders.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
getmorefigures.php?uid=PMC4114715&req=5

f1-ol-08-03-1147: Abdominal computed tomography of the patient with primary adrenal nodular lymphocyte-predominant Hodgkin lymphoma. A soft tissue mass was observed in the left adrenal gland (arrow), measuring 4.5×5.5 cm, with a less uniform density and clear borders.

Mentions: A 36-year-old male presented at The Second Xiangya Hospital of Central South University (Changsha, China) with high fever and weight loss lasting for 10 days, as well as a left adrenal mass that had been identified one week previously. The patient had no history of hypertension and physical examination showed no abnormalities. A total body computed tomography (CT) scan revealed the presence of a large left adrenal mass measuring 4.5×5.5 cm in size (Fig. 1). No obvious abnormalities in the right adrenal gland, retroperitoneal area and other parts of the body were identified by CT. Bone marrow aspiration and biopsy were normal. Plasma metanephrine, plasma renin activity, serum aldosterone, dehydroepiandrosterone and basic metabolic panel test results were all normal. Routine hematological parameters and liver and kidney function tests were normal. Hepatitis B and C and human immunodeficiency virus serology test results were negative. In addition, Epstein-Barr virus (EBV) serology showed negativity for immunoglobulin M (IgM) and IgG antibodies. The patient subsequently underwent laparoscopic left adrenalectomy.


Primary adrenal nodular lymphocyte-predominant Hodgkin lymphoma: A case report and review of the literature.

Wang J, Ma J, Hu C, Li D, She X - Oncol Lett (2014)

Abdominal computed tomography of the patient with primary adrenal nodular lymphocyte-predominant Hodgkin lymphoma. A soft tissue mass was observed in the left adrenal gland (arrow), measuring 4.5×5.5 cm, with a less uniform density and clear borders.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4114715&req=5

f1-ol-08-03-1147: Abdominal computed tomography of the patient with primary adrenal nodular lymphocyte-predominant Hodgkin lymphoma. A soft tissue mass was observed in the left adrenal gland (arrow), measuring 4.5×5.5 cm, with a less uniform density and clear borders.
Mentions: A 36-year-old male presented at The Second Xiangya Hospital of Central South University (Changsha, China) with high fever and weight loss lasting for 10 days, as well as a left adrenal mass that had been identified one week previously. The patient had no history of hypertension and physical examination showed no abnormalities. A total body computed tomography (CT) scan revealed the presence of a large left adrenal mass measuring 4.5×5.5 cm in size (Fig. 1). No obvious abnormalities in the right adrenal gland, retroperitoneal area and other parts of the body were identified by CT. Bone marrow aspiration and biopsy were normal. Plasma metanephrine, plasma renin activity, serum aldosterone, dehydroepiandrosterone and basic metabolic panel test results were all normal. Routine hematological parameters and liver and kidney function tests were normal. Hepatitis B and C and human immunodeficiency virus serology test results were negative. In addition, Epstein-Barr virus (EBV) serology showed negativity for immunoglobulin M (IgM) and IgG antibodies. The patient subsequently underwent laparoscopic left adrenalectomy.

Bottom Line: The patient was without specific clinical signs and the definitive diagnosis was achieved by histological study.Given the rarity of this disease, there are limited experiences with regard to its diagnosis and treatment.This study is useful for the differential diagnosis and treatment of adrenal masses.

View Article: PubMed Central - PubMed

Affiliation: Department of Oncology, The Second Xiangya Hospital of Central South University, Changsha, Hunan 410011, P.R. China.

ABSTRACT
Nodular lymphocyte-predominant Hodgkin lymphoma (NLPHL) is a subtype of Hodgkin lymphoma (HL), and is a rare disease manifestation in the adrenal gland, which is difficult to be diagnosed and treated. In the present study, we report a case of primary adrenal NLPHL in a 36-year-old male patient. The patient was without specific clinical signs and the definitive diagnosis was achieved by histological study. The patient underwent a laparoscopic left adrenalectomy and chemotherapy regimen of doxorubicin, bleomycin, vinblastine and dacarbazine (ABVD). There is no standard treatment for adrenal NLPHL and therefore, treatment is based on that for other types of NLPHL, which includes radiotherapy and ABVD chemotherapy. Given the rarity of this disease, there are limited experiences with regard to its diagnosis and treatment. This study is useful for the differential diagnosis and treatment of adrenal masses.

No MeSH data available.


Related in: MedlinePlus