Limits...
Primary neuroendocrine small cell carcinoma of the parotid gland: A case report and review of the literature.

Liu M, Zhong M, Sun C - Oncol Lett (2014)

Bottom Line: An extended resection of the right parotid gland mass and dissection of the facial nerve were performed.Following discharge from the hospital, the patient received radiation therapy postoperatively.The patient has remained disease free during five months of follow-up.

View Article: PubMed Central - PubMed

Affiliation: Department of Oromaxillofacial-Head and Neck Surgery, School of Stomatology, China Medical University, Shenyang, Liaoning 110002, P.R. China.

ABSTRACT
Small cell carcinoma (SCC) is a malignant epithelial tumor that predominantly arises in the lungs. Primary SCC of the parotid gland is rare and difficult to diagnose by analysis of frozen sections obtained during surgery. Due to the aggressive nature of SCC and the frequent occurrence of distant metastases, identification of the disease is important. The current study reports the case of a male patient who presented with a right parotid gland mass. The tumor was resected and evaluated by light microscopy and immunohistochemical analysis. Immunohistochemically, the tumor was positive for cytokeratin, epithelial membrane antigen, cluster of differentiation 117, synaptophysin and thyroid transcription factor-1, which indicated that the tumor was a SCC of the parotid gland. An extended resection of the right parotid gland mass and dissection of the facial nerve were performed. Following discharge from the hospital, the patient received radiation therapy postoperatively. The patient has remained disease free during five months of follow-up.

No MeSH data available.


Related in: MedlinePlus

Ultrasonography of the parotid gland.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
getmorefigures.php?uid=PMC4114714&req=5

f1-ol-08-03-1275: Ultrasonography of the parotid gland.

Mentions: A 59-year-old male consulted to the Department of Oromaxillofacial-Head and Neck Surgery, School of Stomatology, China Medical University (Shenyang, China) due to a painless mass in the right parotid that had been progressively enlarging for two months. Upon admission, facial nerve palsy was not observed, and the mass appeared to be nodular. Ultrasonography revealed a 2.2×1.5-cm well-defined hypoechoic lesion in the right parotid gland (Fig. 1). A computed tomography (CT) scan of the thorax and ultrasonography of the thyroid gland did not reveal any involvement of other sites. An ‘S’ incision was made from the front of the earlobe to the jaw, separate and protecting the mandible branch and cervical branch of the facial nerve. The tumor was located behind and below the cervical branch of the facial nerve. Adhesions were located between the tumor and great auricular nerve, additionally enlarged lymph nodes were located beside the tumor. An extended resection of the right parotid gland mass, excision of the great auricular nerve and dissection of the facial nerve were subsequently performed. Following surgery, the patient received post-operative radiation therapy and remained disease-free during five months of follow-up.


Primary neuroendocrine small cell carcinoma of the parotid gland: A case report and review of the literature.

Liu M, Zhong M, Sun C - Oncol Lett (2014)

Ultrasonography of the parotid gland.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4114714&req=5

f1-ol-08-03-1275: Ultrasonography of the parotid gland.
Mentions: A 59-year-old male consulted to the Department of Oromaxillofacial-Head and Neck Surgery, School of Stomatology, China Medical University (Shenyang, China) due to a painless mass in the right parotid that had been progressively enlarging for two months. Upon admission, facial nerve palsy was not observed, and the mass appeared to be nodular. Ultrasonography revealed a 2.2×1.5-cm well-defined hypoechoic lesion in the right parotid gland (Fig. 1). A computed tomography (CT) scan of the thorax and ultrasonography of the thyroid gland did not reveal any involvement of other sites. An ‘S’ incision was made from the front of the earlobe to the jaw, separate and protecting the mandible branch and cervical branch of the facial nerve. The tumor was located behind and below the cervical branch of the facial nerve. Adhesions were located between the tumor and great auricular nerve, additionally enlarged lymph nodes were located beside the tumor. An extended resection of the right parotid gland mass, excision of the great auricular nerve and dissection of the facial nerve were subsequently performed. Following surgery, the patient received post-operative radiation therapy and remained disease-free during five months of follow-up.

Bottom Line: An extended resection of the right parotid gland mass and dissection of the facial nerve were performed.Following discharge from the hospital, the patient received radiation therapy postoperatively.The patient has remained disease free during five months of follow-up.

View Article: PubMed Central - PubMed

Affiliation: Department of Oromaxillofacial-Head and Neck Surgery, School of Stomatology, China Medical University, Shenyang, Liaoning 110002, P.R. China.

ABSTRACT
Small cell carcinoma (SCC) is a malignant epithelial tumor that predominantly arises in the lungs. Primary SCC of the parotid gland is rare and difficult to diagnose by analysis of frozen sections obtained during surgery. Due to the aggressive nature of SCC and the frequent occurrence of distant metastases, identification of the disease is important. The current study reports the case of a male patient who presented with a right parotid gland mass. The tumor was resected and evaluated by light microscopy and immunohistochemical analysis. Immunohistochemically, the tumor was positive for cytokeratin, epithelial membrane antigen, cluster of differentiation 117, synaptophysin and thyroid transcription factor-1, which indicated that the tumor was a SCC of the parotid gland. An extended resection of the right parotid gland mass and dissection of the facial nerve were performed. Following discharge from the hospital, the patient received radiation therapy postoperatively. The patient has remained disease free during five months of follow-up.

No MeSH data available.


Related in: MedlinePlus