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Progression of penile cutaneous horn to squamous cell carcinoma: A case report.

Zhou Y, Tang Y, Tang J, Xia B, Dai Y - Oncol Lett (2014)

Bottom Line: The current report presents the case of a 43-year-old male suffering from a penile cutaneous horn.A surgical excision of the lesion was performed and histopathology demonstrated hyperkeratosis, dyskeratosis and epithelial hyperplasia.The International Index of Erectile Function 5 questionnaire was used to assess the patient and the score had decreased in the one-month postoperative follow-up compared with that of the preoperative period.

View Article: PubMed Central - PubMed

Affiliation: Department of Urology, The Third Xiangya Hospital of Central South University, Changsha, Hunan 410013, P.R. China.

ABSTRACT
The current report presents the case of a 43-year-old male suffering from a penile cutaneous horn. A surgical excision of the lesion was performed and histopathology demonstrated hyperkeratosis, dyskeratosis and epithelial hyperplasia. The cutaneous horn progressed to squamous cell carcinoma <1.5 months following surgery and a partial penectomy was conducted. The International Index of Erectile Function 5 questionnaire was used to assess the patient and the score had decreased in the one-month postoperative follow-up compared with that of the preoperative period. These findings indicate that undergoing a partial penectomy on initial diagnosis of a penile cutaneous horn should be considered in order to conserve a greater quantity of the penile tissue and improve the postoperative quality of life.

No MeSH data available.


Related in: MedlinePlus

Histopathological staining identifying the lesion as a well differentiated squamous cell carcinoma (haematoxylin and eosin stain; magnification, ×200).
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f4-ol-08-03-1211: Histopathological staining identifying the lesion as a well differentiated squamous cell carcinoma (haematoxylin and eosin stain; magnification, ×200).

Mentions: The first postoperative visit was conducted on day 39 following surgery, the patient presented with a painful swelling over the glans penis and purulent discharge of the urethra. On examination, the glans penis was stiff and there was a ~5-mm nodular lesion on the distal aspect of the penile shaft. Pelvic magnetic resonance imaging (MRI) revealed a lesion with an unclear boundary measuring 0.6 cm in diameter (Fig. 3). A biopsy was performed and histopathology indicated squamous atypia and suspected squamous cell carcinoma. Finally, the patient consented to a partial penectomy and histopathology revealed a well differentiated squamous cell carcinoma (Fig. 4). A six-month postoperative follow-up was conducted and the patient was able to urinate whilst standing and the IIEF-5 score was 15 (moderate). Follow-up of the patient is ongoing.


Progression of penile cutaneous horn to squamous cell carcinoma: A case report.

Zhou Y, Tang Y, Tang J, Xia B, Dai Y - Oncol Lett (2014)

Histopathological staining identifying the lesion as a well differentiated squamous cell carcinoma (haematoxylin and eosin stain; magnification, ×200).
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4114708&req=5

f4-ol-08-03-1211: Histopathological staining identifying the lesion as a well differentiated squamous cell carcinoma (haematoxylin and eosin stain; magnification, ×200).
Mentions: The first postoperative visit was conducted on day 39 following surgery, the patient presented with a painful swelling over the glans penis and purulent discharge of the urethra. On examination, the glans penis was stiff and there was a ~5-mm nodular lesion on the distal aspect of the penile shaft. Pelvic magnetic resonance imaging (MRI) revealed a lesion with an unclear boundary measuring 0.6 cm in diameter (Fig. 3). A biopsy was performed and histopathology indicated squamous atypia and suspected squamous cell carcinoma. Finally, the patient consented to a partial penectomy and histopathology revealed a well differentiated squamous cell carcinoma (Fig. 4). A six-month postoperative follow-up was conducted and the patient was able to urinate whilst standing and the IIEF-5 score was 15 (moderate). Follow-up of the patient is ongoing.

Bottom Line: The current report presents the case of a 43-year-old male suffering from a penile cutaneous horn.A surgical excision of the lesion was performed and histopathology demonstrated hyperkeratosis, dyskeratosis and epithelial hyperplasia.The International Index of Erectile Function 5 questionnaire was used to assess the patient and the score had decreased in the one-month postoperative follow-up compared with that of the preoperative period.

View Article: PubMed Central - PubMed

Affiliation: Department of Urology, The Third Xiangya Hospital of Central South University, Changsha, Hunan 410013, P.R. China.

ABSTRACT
The current report presents the case of a 43-year-old male suffering from a penile cutaneous horn. A surgical excision of the lesion was performed and histopathology demonstrated hyperkeratosis, dyskeratosis and epithelial hyperplasia. The cutaneous horn progressed to squamous cell carcinoma <1.5 months following surgery and a partial penectomy was conducted. The International Index of Erectile Function 5 questionnaire was used to assess the patient and the score had decreased in the one-month postoperative follow-up compared with that of the preoperative period. These findings indicate that undergoing a partial penectomy on initial diagnosis of a penile cutaneous horn should be considered in order to conserve a greater quantity of the penile tissue and improve the postoperative quality of life.

No MeSH data available.


Related in: MedlinePlus