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Osteosarcoma arising from the parapharyngeal space: A case report.

Hoshi M, Takada J, Oebisu N, Nakamura H - Oncol Lett (2014)

Bottom Line: Lung CT also showed multiple lung metastases at the time of the first visit to the Department of Orthopedic Surgery, Osaka City University Graduate School of Medicine (Osaka, Japan).The patient was alive at the 24-month follow-up subsequent to this treatment.Although a definitive diagnosis requires the use of a biopsy, the CT and MRI findings described in the present study suggest inclusion of this rare tumor in the differential diagnosis that is formed when such findings occur in the parapharyngeal space.

View Article: PubMed Central - PubMed

Affiliation: Department of Orthopedic Surgery, Osaka City University Graduate School of Medicine, Osaka 545-8585, Japan.

ABSTRACT
The current study presents a rare case of osteoblastic osteosarcoma arising from an extremely rare site, namely, the parapharyngeal space. To the best of our knowledge, this is the first study of computed tomography (CT) and magnetic resonance imaging (MRI) of an osteosarcoma in the parapharyngeal space with pathological correlation. A 56-year-old male presented with a mass of the right facial region. CT and MRI showed a heterogeneous mass, with ossification or calcification, occupying the parapharyngeal space. Open biopsy revealed an osteoblastic osteosarcoma containing calcified malignant osteoid. Lung CT also showed multiple lung metastases at the time of the first visit to the Department of Orthopedic Surgery, Osaka City University Graduate School of Medicine (Osaka, Japan). Systemic chemotherapy and radiotherapy were administered to the patient for palliation. The patient was alive at the 24-month follow-up subsequent to this treatment. Although a definitive diagnosis requires the use of a biopsy, the CT and MRI findings described in the present study suggest inclusion of this rare tumor in the differential diagnosis that is formed when such findings occur in the parapharyngeal space. The present study also briefly discusses osteosarcoma of the parapharyngeal space.

No MeSH data available.


Related in: MedlinePlus

Low-intensity within an isointensity mass on an axial view of magnetic resonance imaging showing ossification in the tumor on (A) T1- and (B) T2-weighted images.
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f2-ol-08-03-1240: Low-intensity within an isointensity mass on an axial view of magnetic resonance imaging showing ossification in the tumor on (A) T1- and (B) T2-weighted images.

Mentions: A 56-year-old male presented with a mass in the right facial bone that had been apparent for three months, and dysesthesia, which had occurred gradually at this site. The patient incidentally identified the tumor and visited Wakakusa-Daiichi Hospital, Higashi-Osaka (Osaka, Japan), where the mass was confirmed with computed tomography (CT) examination. Nothing of note was found in the patient’s past medical and family histories, and the findings from the routine laboratory studies were within the normal limits. Plain X-rays showed no particular findings, but regional CT showed a soft-tissue mass with prominent ossification in the central region, and involving the parapharyngeal space (Fig. 1), in which the anterior septum ballooned owing to compression from the mass. Magnetic resonance imaging (MRI) revealed heterogeneously low intensity to isointensity results on T1-weighted sequences and low to moderately high intensity results on T2-weighted images, with a size of 5.6×4.8 cm (Fig. 2). Lung CT revealed multiple small nodules that were suspected to be lung metastases (Fig. 3).


Osteosarcoma arising from the parapharyngeal space: A case report.

Hoshi M, Takada J, Oebisu N, Nakamura H - Oncol Lett (2014)

Low-intensity within an isointensity mass on an axial view of magnetic resonance imaging showing ossification in the tumor on (A) T1- and (B) T2-weighted images.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4114581&req=5

f2-ol-08-03-1240: Low-intensity within an isointensity mass on an axial view of magnetic resonance imaging showing ossification in the tumor on (A) T1- and (B) T2-weighted images.
Mentions: A 56-year-old male presented with a mass in the right facial bone that had been apparent for three months, and dysesthesia, which had occurred gradually at this site. The patient incidentally identified the tumor and visited Wakakusa-Daiichi Hospital, Higashi-Osaka (Osaka, Japan), where the mass was confirmed with computed tomography (CT) examination. Nothing of note was found in the patient’s past medical and family histories, and the findings from the routine laboratory studies were within the normal limits. Plain X-rays showed no particular findings, but regional CT showed a soft-tissue mass with prominent ossification in the central region, and involving the parapharyngeal space (Fig. 1), in which the anterior septum ballooned owing to compression from the mass. Magnetic resonance imaging (MRI) revealed heterogeneously low intensity to isointensity results on T1-weighted sequences and low to moderately high intensity results on T2-weighted images, with a size of 5.6×4.8 cm (Fig. 2). Lung CT revealed multiple small nodules that were suspected to be lung metastases (Fig. 3).

Bottom Line: Lung CT also showed multiple lung metastases at the time of the first visit to the Department of Orthopedic Surgery, Osaka City University Graduate School of Medicine (Osaka, Japan).The patient was alive at the 24-month follow-up subsequent to this treatment.Although a definitive diagnosis requires the use of a biopsy, the CT and MRI findings described in the present study suggest inclusion of this rare tumor in the differential diagnosis that is formed when such findings occur in the parapharyngeal space.

View Article: PubMed Central - PubMed

Affiliation: Department of Orthopedic Surgery, Osaka City University Graduate School of Medicine, Osaka 545-8585, Japan.

ABSTRACT
The current study presents a rare case of osteoblastic osteosarcoma arising from an extremely rare site, namely, the parapharyngeal space. To the best of our knowledge, this is the first study of computed tomography (CT) and magnetic resonance imaging (MRI) of an osteosarcoma in the parapharyngeal space with pathological correlation. A 56-year-old male presented with a mass of the right facial region. CT and MRI showed a heterogeneous mass, with ossification or calcification, occupying the parapharyngeal space. Open biopsy revealed an osteoblastic osteosarcoma containing calcified malignant osteoid. Lung CT also showed multiple lung metastases at the time of the first visit to the Department of Orthopedic Surgery, Osaka City University Graduate School of Medicine (Osaka, Japan). Systemic chemotherapy and radiotherapy were administered to the patient for palliation. The patient was alive at the 24-month follow-up subsequent to this treatment. Although a definitive diagnosis requires the use of a biopsy, the CT and MRI findings described in the present study suggest inclusion of this rare tumor in the differential diagnosis that is formed when such findings occur in the parapharyngeal space. The present study also briefly discusses osteosarcoma of the parapharyngeal space.

No MeSH data available.


Related in: MedlinePlus