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Squamous cell carcinoma developing in the scar of Fournier's gangrene--case report.

- BMC Cancer (2004)

Bottom Line: A 65-year-old gentleman presented with a small non-healing ulcer developing on right hemi-scrotum two years after the treatment for Fournier's gangrene.On histological examination it was found to be squamous cell carcinoma.Squamous cell carcinoma can develop in the scar of Fournier's gangrene after a long delay, which differentiates it from other scar carcinomas or Marjolin's ulcer.

View Article: PubMed Central - HTML - PubMed

Affiliation: Department of surgery, Indian Council of Medical Research, Vardhman Mahavir Medical College, Safdarjang Hospital, New Delhi 110023, India. chintamani7@rediffmail.com

ABSTRACT

Background: Squamous cell carcinoma of the scrotum is rare and its development in the scar of Fournier's gangrene is still rarer.

Case presentation: A 65-year-old gentleman presented with a small non-healing ulcer developing on right hemi-scrotum two years after the treatment for Fournier's gangrene. On histological examination it was found to be squamous cell carcinoma. He was successfully managed by surgery in the form of wide local excision and ilio-inguinal lymph node dissection followed by adjuvant radiotherapy and chemotherapy.

Conclusions: Squamous cell carcinoma can develop in the scar of Fournier's gangrene after a long delay, which differentiates it from other scar carcinomas or Marjolin's ulcer.

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Related in: MedlinePlus

The resected specimen showing the excised Primary lesion along with lymph nodes (en bloc specimen).
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Figure 3: The resected specimen showing the excised Primary lesion along with lymph nodes (en bloc specimen).

Mentions: The patient was put on antibiotics (third generation cephalosporin, cefotaxime 1 gm intravenously 12 hourly) and provided local wound care using antiseptic dressings of iodine preparations (Betadine). General care in the form of adequate nutrition and hydration was also provided. The incisional biopsy taken from the ulcer edge revealed a poorly differentiated squamous cell carcinoma of the scrotum (there were highly anaplastic, rounded cells with foci of necrosis and dyskeratosis). The patient was prepared for surgery and a wide local excision amounting to right hemiscrotectomy and placement of the right testes in left hemiscrotum through the median raphe was done (Fig. 2). Right ilio-inguinal block dissection was performed en bloc i.e. the lymph nodes were removed in continuity with the primary tumour (Fig. 3).


Squamous cell carcinoma developing in the scar of Fournier's gangrene--case report.

- BMC Cancer (2004)

The resected specimen showing the excised Primary lesion along with lymph nodes (en bloc specimen).
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC411041&req=5

Figure 3: The resected specimen showing the excised Primary lesion along with lymph nodes (en bloc specimen).
Mentions: The patient was put on antibiotics (third generation cephalosporin, cefotaxime 1 gm intravenously 12 hourly) and provided local wound care using antiseptic dressings of iodine preparations (Betadine). General care in the form of adequate nutrition and hydration was also provided. The incisional biopsy taken from the ulcer edge revealed a poorly differentiated squamous cell carcinoma of the scrotum (there were highly anaplastic, rounded cells with foci of necrosis and dyskeratosis). The patient was prepared for surgery and a wide local excision amounting to right hemiscrotectomy and placement of the right testes in left hemiscrotum through the median raphe was done (Fig. 2). Right ilio-inguinal block dissection was performed en bloc i.e. the lymph nodes were removed in continuity with the primary tumour (Fig. 3).

Bottom Line: A 65-year-old gentleman presented with a small non-healing ulcer developing on right hemi-scrotum two years after the treatment for Fournier's gangrene.On histological examination it was found to be squamous cell carcinoma.Squamous cell carcinoma can develop in the scar of Fournier's gangrene after a long delay, which differentiates it from other scar carcinomas or Marjolin's ulcer.

View Article: PubMed Central - HTML - PubMed

Affiliation: Department of surgery, Indian Council of Medical Research, Vardhman Mahavir Medical College, Safdarjang Hospital, New Delhi 110023, India. chintamani7@rediffmail.com

ABSTRACT

Background: Squamous cell carcinoma of the scrotum is rare and its development in the scar of Fournier's gangrene is still rarer.

Case presentation: A 65-year-old gentleman presented with a small non-healing ulcer developing on right hemi-scrotum two years after the treatment for Fournier's gangrene. On histological examination it was found to be squamous cell carcinoma. He was successfully managed by surgery in the form of wide local excision and ilio-inguinal lymph node dissection followed by adjuvant radiotherapy and chemotherapy.

Conclusions: Squamous cell carcinoma can develop in the scar of Fournier's gangrene after a long delay, which differentiates it from other scar carcinomas or Marjolin's ulcer.

Show MeSH
Related in: MedlinePlus