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Squamous cell carcinoma developing in the scar of Fournier's gangrene--case report.

- BMC Cancer (2004)

Bottom Line: A 65-year-old gentleman presented with a small non-healing ulcer developing on right hemi-scrotum two years after the treatment for Fournier's gangrene.On histological examination it was found to be squamous cell carcinoma.Squamous cell carcinoma can develop in the scar of Fournier's gangrene after a long delay, which differentiates it from other scar carcinomas or Marjolin's ulcer.

View Article: PubMed Central - HTML - PubMed

Affiliation: Department of surgery, Indian Council of Medical Research, Vardhman Mahavir Medical College, Safdarjang Hospital, New Delhi 110023, India. chintamani7@rediffmail.com

ABSTRACT

Background: Squamous cell carcinoma of the scrotum is rare and its development in the scar of Fournier's gangrene is still rarer.

Case presentation: A 65-year-old gentleman presented with a small non-healing ulcer developing on right hemi-scrotum two years after the treatment for Fournier's gangrene. On histological examination it was found to be squamous cell carcinoma. He was successfully managed by surgery in the form of wide local excision and ilio-inguinal lymph node dissection followed by adjuvant radiotherapy and chemotherapy.

Conclusions: Squamous cell carcinoma can develop in the scar of Fournier's gangrene after a long delay, which differentiates it from other scar carcinomas or Marjolin's ulcer.

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Related in: MedlinePlus

The clinical and preoperative picture showing the ulcero-proliferative lesion on the right side of the scrotum. The healed scar of previous debridement done for necrotizing fascitis on the anterior abdominal wall can also been seen.
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Figure 1: The clinical and preoperative picture showing the ulcero-proliferative lesion on the right side of the scrotum. The healed scar of previous debridement done for necrotizing fascitis on the anterior abdominal wall can also been seen.

Mentions: There was a 6 × 7 cm, fungating, ulcero-proliferative growth with everted edges on the right hemiscrotum, which was fixed to the underlying tissues (Fig. 1). The scar on the left hemiscrotum and the anterior abdominal wall was supple and well healed. Inguinal group of lymph nodes on the right-hand side (both the horizontal and vertical chain) were enlarged, hard and mobile. All the other systems were clinically normal. Routine investigations including hemogram (Hb: 13 gm%, total counts: 6000/cmm), blood sugar, kidney function tests, liver function tests and urine examination were essentially within normal limits. X-ray chest and electrocardiogram were also normal. Ultrasonographic examination and contrast enhanced computed tomography of the abdomen did not reveal any abnormality except the enlarged iliac and inguinal group of lymph nodes on the right-hand side. Bladder, kidneys and the left hemiscrotum were normal.


Squamous cell carcinoma developing in the scar of Fournier's gangrene--case report.

- BMC Cancer (2004)

The clinical and preoperative picture showing the ulcero-proliferative lesion on the right side of the scrotum. The healed scar of previous debridement done for necrotizing fascitis on the anterior abdominal wall can also been seen.
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC411041&req=5

Figure 1: The clinical and preoperative picture showing the ulcero-proliferative lesion on the right side of the scrotum. The healed scar of previous debridement done for necrotizing fascitis on the anterior abdominal wall can also been seen.
Mentions: There was a 6 × 7 cm, fungating, ulcero-proliferative growth with everted edges on the right hemiscrotum, which was fixed to the underlying tissues (Fig. 1). The scar on the left hemiscrotum and the anterior abdominal wall was supple and well healed. Inguinal group of lymph nodes on the right-hand side (both the horizontal and vertical chain) were enlarged, hard and mobile. All the other systems were clinically normal. Routine investigations including hemogram (Hb: 13 gm%, total counts: 6000/cmm), blood sugar, kidney function tests, liver function tests and urine examination were essentially within normal limits. X-ray chest and electrocardiogram were also normal. Ultrasonographic examination and contrast enhanced computed tomography of the abdomen did not reveal any abnormality except the enlarged iliac and inguinal group of lymph nodes on the right-hand side. Bladder, kidneys and the left hemiscrotum were normal.

Bottom Line: A 65-year-old gentleman presented with a small non-healing ulcer developing on right hemi-scrotum two years after the treatment for Fournier's gangrene.On histological examination it was found to be squamous cell carcinoma.Squamous cell carcinoma can develop in the scar of Fournier's gangrene after a long delay, which differentiates it from other scar carcinomas or Marjolin's ulcer.

View Article: PubMed Central - HTML - PubMed

Affiliation: Department of surgery, Indian Council of Medical Research, Vardhman Mahavir Medical College, Safdarjang Hospital, New Delhi 110023, India. chintamani7@rediffmail.com

ABSTRACT

Background: Squamous cell carcinoma of the scrotum is rare and its development in the scar of Fournier's gangrene is still rarer.

Case presentation: A 65-year-old gentleman presented with a small non-healing ulcer developing on right hemi-scrotum two years after the treatment for Fournier's gangrene. On histological examination it was found to be squamous cell carcinoma. He was successfully managed by surgery in the form of wide local excision and ilio-inguinal lymph node dissection followed by adjuvant radiotherapy and chemotherapy.

Conclusions: Squamous cell carcinoma can develop in the scar of Fournier's gangrene after a long delay, which differentiates it from other scar carcinomas or Marjolin's ulcer.

Show MeSH
Related in: MedlinePlus