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Systemic mastocytosis - a diagnostic challenge.

Lladó AC, Mihon CE, Silva M, Galzerano A - Rev Bras Hematol Hemoter (2014)

Bottom Line: The histopathologic analysis is essential for definitive diagnosis but there is no curative treatment.This is a rare clinical case of aggressive systemic mastocytosis for which palliative treatment can improve survival and quality of life.A brief review of the literature about this pathology is also included.

View Article: PubMed Central - PubMed

Affiliation: Hospital Santo António dos Capuchos, Lisbon, Portugal; Centro Hospitalar de Lisboa Central, Lisbon, Portugal. Electronic address: ana.llado@sapo.pt.

No MeSH data available.


Related in: MedlinePlus

Computed tomography scan of the lumbar spine and sacrum – scattered osteosclerotic lesions on vertebrae, sacrum and iliac bones (coronal view).
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fig0005: Computed tomography scan of the lumbar spine and sacrum – scattered osteosclerotic lesions on vertebrae, sacrum and iliac bones (coronal view).

Mentions: A 72-year-old Caucasian woman with a history of diverticulosis, surgically-corrected lumbar hernia and plurisegmental degenerative osteoarticular disease is reported. There was no background of allergies, smoking or alcoholism and she was taking only analgesic medications. In May 2012, she was admitted for acute diverticulitis. During her hospital stay the lower back pain worsened and so a computed tomography (CT) scan of the lumbar spine was performed which documented diffuse osteopenia and multiple scattered osteosclerotic lesions on vertebrae, the sacrum and the iliac bones (Figure 1). After discharge and with a presumptive diagnosis of occult neoplastic disorder, she was referred to her doctor for further studies.


Systemic mastocytosis - a diagnostic challenge.

Lladó AC, Mihon CE, Silva M, Galzerano A - Rev Bras Hematol Hemoter (2014)

Computed tomography scan of the lumbar spine and sacrum – scattered osteosclerotic lesions on vertebrae, sacrum and iliac bones (coronal view).
© Copyright Policy - CC BY-NC-ND
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4109736&req=5

fig0005: Computed tomography scan of the lumbar spine and sacrum – scattered osteosclerotic lesions on vertebrae, sacrum and iliac bones (coronal view).
Mentions: A 72-year-old Caucasian woman with a history of diverticulosis, surgically-corrected lumbar hernia and plurisegmental degenerative osteoarticular disease is reported. There was no background of allergies, smoking or alcoholism and she was taking only analgesic medications. In May 2012, she was admitted for acute diverticulitis. During her hospital stay the lower back pain worsened and so a computed tomography (CT) scan of the lumbar spine was performed which documented diffuse osteopenia and multiple scattered osteosclerotic lesions on vertebrae, the sacrum and the iliac bones (Figure 1). After discharge and with a presumptive diagnosis of occult neoplastic disorder, she was referred to her doctor for further studies.

Bottom Line: The histopathologic analysis is essential for definitive diagnosis but there is no curative treatment.This is a rare clinical case of aggressive systemic mastocytosis for which palliative treatment can improve survival and quality of life.A brief review of the literature about this pathology is also included.

View Article: PubMed Central - PubMed

Affiliation: Hospital Santo António dos Capuchos, Lisbon, Portugal; Centro Hospitalar de Lisboa Central, Lisbon, Portugal. Electronic address: ana.llado@sapo.pt.

No MeSH data available.


Related in: MedlinePlus