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Stereotactic body radiotherapy for small lung tumors in the University of Tokyo Hospital.

Yamashita H, Takahashi W, Haga A, Kida S, Saotome N, Nakagawa K - Biomed Res Int (2014)

Bottom Line: Our work on stereotactic body radiation therapy (SBRT) for primary and metastatic lung tumors will be described.The eligibility criteria for SBRT, our previous SBRT method, the definition of target volume, heterogeneity correction, the position adjustment using four-dimensional cone-beam computed tomography (4D CBCT) immediately before SBRT, volumetric modulated arc therapy (VMAT) method for SBRT, verifying of tumor position within internal target volume (ITV) using in-treatment 4D-CBCT during VMAT-SBRT, shortening of treatment time using flattening-filter-free (FFF) techniques, delivery of 4D dose calculation for lung-VMAT patients using in-treatment CBCT and LINAC log data with agility multileaf collimator, and SBRT method for centrally located lung tumors in our institution will be shown.In our institution, these efforts have been made with the goal of raising the local control rate and decreasing adverse effects after SBRT.

View Article: PubMed Central - PubMed

Affiliation: Department of Radiology, The University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan.

ABSTRACT
Our work on stereotactic body radiation therapy (SBRT) for primary and metastatic lung tumors will be described. The eligibility criteria for SBRT, our previous SBRT method, the definition of target volume, heterogeneity correction, the position adjustment using four-dimensional cone-beam computed tomography (4D CBCT) immediately before SBRT, volumetric modulated arc therapy (VMAT) method for SBRT, verifying of tumor position within internal target volume (ITV) using in-treatment 4D-CBCT during VMAT-SBRT, shortening of treatment time using flattening-filter-free (FFF) techniques, delivery of 4D dose calculation for lung-VMAT patients using in-treatment CBCT and LINAC log data with agility multileaf collimator, and SBRT method for centrally located lung tumors in our institution will be shown. In our institution, these efforts have been made with the goal of raising the local control rate and decreasing adverse effects after SBRT.

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A comparison of calculated dose distributions for the VMAT plan with (a) FF and (b) FFF [10].
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fig7: A comparison of calculated dose distributions for the VMAT plan with (a) FF and (b) FFF [10].

Mentions: We have successfully shown an advantage of the FFF configuration in terms of dose delivery times for stereotactic lung VMAT [10]. A shorter delivery time ensures more accurate tumor positioning during treatment and possibly greater tumor control. It was also demonstrated that 4D CBCT-based tumor registration is feasible with FFF delivery (Figure 7).


Stereotactic body radiotherapy for small lung tumors in the University of Tokyo Hospital.

Yamashita H, Takahashi W, Haga A, Kida S, Saotome N, Nakagawa K - Biomed Res Int (2014)

A comparison of calculated dose distributions for the VMAT plan with (a) FF and (b) FFF [10].
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4109604&req=5

fig7: A comparison of calculated dose distributions for the VMAT plan with (a) FF and (b) FFF [10].
Mentions: We have successfully shown an advantage of the FFF configuration in terms of dose delivery times for stereotactic lung VMAT [10]. A shorter delivery time ensures more accurate tumor positioning during treatment and possibly greater tumor control. It was also demonstrated that 4D CBCT-based tumor registration is feasible with FFF delivery (Figure 7).

Bottom Line: Our work on stereotactic body radiation therapy (SBRT) for primary and metastatic lung tumors will be described.The eligibility criteria for SBRT, our previous SBRT method, the definition of target volume, heterogeneity correction, the position adjustment using four-dimensional cone-beam computed tomography (4D CBCT) immediately before SBRT, volumetric modulated arc therapy (VMAT) method for SBRT, verifying of tumor position within internal target volume (ITV) using in-treatment 4D-CBCT during VMAT-SBRT, shortening of treatment time using flattening-filter-free (FFF) techniques, delivery of 4D dose calculation for lung-VMAT patients using in-treatment CBCT and LINAC log data with agility multileaf collimator, and SBRT method for centrally located lung tumors in our institution will be shown.In our institution, these efforts have been made with the goal of raising the local control rate and decreasing adverse effects after SBRT.

View Article: PubMed Central - PubMed

Affiliation: Department of Radiology, The University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan.

ABSTRACT
Our work on stereotactic body radiation therapy (SBRT) for primary and metastatic lung tumors will be described. The eligibility criteria for SBRT, our previous SBRT method, the definition of target volume, heterogeneity correction, the position adjustment using four-dimensional cone-beam computed tomography (4D CBCT) immediately before SBRT, volumetric modulated arc therapy (VMAT) method for SBRT, verifying of tumor position within internal target volume (ITV) using in-treatment 4D-CBCT during VMAT-SBRT, shortening of treatment time using flattening-filter-free (FFF) techniques, delivery of 4D dose calculation for lung-VMAT patients using in-treatment CBCT and LINAC log data with agility multileaf collimator, and SBRT method for centrally located lung tumors in our institution will be shown. In our institution, these efforts have been made with the goal of raising the local control rate and decreasing adverse effects after SBRT.

Show MeSH
Related in: MedlinePlus