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Stereotactic body radiotherapy for small lung tumors in the University of Tokyo Hospital.

Yamashita H, Takahashi W, Haga A, Kida S, Saotome N, Nakagawa K - Biomed Res Int (2014)

Bottom Line: Our work on stereotactic body radiation therapy (SBRT) for primary and metastatic lung tumors will be described.The eligibility criteria for SBRT, our previous SBRT method, the definition of target volume, heterogeneity correction, the position adjustment using four-dimensional cone-beam computed tomography (4D CBCT) immediately before SBRT, volumetric modulated arc therapy (VMAT) method for SBRT, verifying of tumor position within internal target volume (ITV) using in-treatment 4D-CBCT during VMAT-SBRT, shortening of treatment time using flattening-filter-free (FFF) techniques, delivery of 4D dose calculation for lung-VMAT patients using in-treatment CBCT and LINAC log data with agility multileaf collimator, and SBRT method for centrally located lung tumors in our institution will be shown.In our institution, these efforts have been made with the goal of raising the local control rate and decreasing adverse effects after SBRT.

View Article: PubMed Central - PubMed

Affiliation: Department of Radiology, The University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan.

ABSTRACT
Our work on stereotactic body radiation therapy (SBRT) for primary and metastatic lung tumors will be described. The eligibility criteria for SBRT, our previous SBRT method, the definition of target volume, heterogeneity correction, the position adjustment using four-dimensional cone-beam computed tomography (4D CBCT) immediately before SBRT, volumetric modulated arc therapy (VMAT) method for SBRT, verifying of tumor position within internal target volume (ITV) using in-treatment 4D-CBCT during VMAT-SBRT, shortening of treatment time using flattening-filter-free (FFF) techniques, delivery of 4D dose calculation for lung-VMAT patients using in-treatment CBCT and LINAC log data with agility multileaf collimator, and SBRT method for centrally located lung tumors in our institution will be shown. In our institution, these efforts have been made with the goal of raising the local control rate and decreasing adverse effects after SBRT.

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Example of the detection of sagittal displacement between the ITV and the actual tumor location, for which the ITV contoured on the planning CT was superimposed onto the in-treatment 4D CBCT image.
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fig6: Example of the detection of sagittal displacement between the ITV and the actual tumor location, for which the ITV contoured on the planning CT was superimposed onto the in-treatment 4D CBCT image.

Mentions: CBCT integrated into a radiation therapy system is a powerful tool in IGRT. The CBCT images acquired just prior to treatment enable us to localize the target accurately and to correct patient positioning. In addition, they have been used in planning adaptive radiation therapy during the course of the treatment [49, 58–61]. However, the CBCT images before treatment may be displaced from the actual location during treatment. Therefore, the ideal is to obtain the image volume in the state of delivered beams, and this is called “in-treatment CBCT” (Figure 6). In our previous paper, we reported that in-treatment CBCT can actually be acquired with rotational treatment such as VMAT [53], and displacement of the target can be evaluated using the volumetric images [62].


Stereotactic body radiotherapy for small lung tumors in the University of Tokyo Hospital.

Yamashita H, Takahashi W, Haga A, Kida S, Saotome N, Nakagawa K - Biomed Res Int (2014)

Example of the detection of sagittal displacement between the ITV and the actual tumor location, for which the ITV contoured on the planning CT was superimposed onto the in-treatment 4D CBCT image.
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4109604&req=5

fig6: Example of the detection of sagittal displacement between the ITV and the actual tumor location, for which the ITV contoured on the planning CT was superimposed onto the in-treatment 4D CBCT image.
Mentions: CBCT integrated into a radiation therapy system is a powerful tool in IGRT. The CBCT images acquired just prior to treatment enable us to localize the target accurately and to correct patient positioning. In addition, they have been used in planning adaptive radiation therapy during the course of the treatment [49, 58–61]. However, the CBCT images before treatment may be displaced from the actual location during treatment. Therefore, the ideal is to obtain the image volume in the state of delivered beams, and this is called “in-treatment CBCT” (Figure 6). In our previous paper, we reported that in-treatment CBCT can actually be acquired with rotational treatment such as VMAT [53], and displacement of the target can be evaluated using the volumetric images [62].

Bottom Line: Our work on stereotactic body radiation therapy (SBRT) for primary and metastatic lung tumors will be described.The eligibility criteria for SBRT, our previous SBRT method, the definition of target volume, heterogeneity correction, the position adjustment using four-dimensional cone-beam computed tomography (4D CBCT) immediately before SBRT, volumetric modulated arc therapy (VMAT) method for SBRT, verifying of tumor position within internal target volume (ITV) using in-treatment 4D-CBCT during VMAT-SBRT, shortening of treatment time using flattening-filter-free (FFF) techniques, delivery of 4D dose calculation for lung-VMAT patients using in-treatment CBCT and LINAC log data with agility multileaf collimator, and SBRT method for centrally located lung tumors in our institution will be shown.In our institution, these efforts have been made with the goal of raising the local control rate and decreasing adverse effects after SBRT.

View Article: PubMed Central - PubMed

Affiliation: Department of Radiology, The University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan.

ABSTRACT
Our work on stereotactic body radiation therapy (SBRT) for primary and metastatic lung tumors will be described. The eligibility criteria for SBRT, our previous SBRT method, the definition of target volume, heterogeneity correction, the position adjustment using four-dimensional cone-beam computed tomography (4D CBCT) immediately before SBRT, volumetric modulated arc therapy (VMAT) method for SBRT, verifying of tumor position within internal target volume (ITV) using in-treatment 4D-CBCT during VMAT-SBRT, shortening of treatment time using flattening-filter-free (FFF) techniques, delivery of 4D dose calculation for lung-VMAT patients using in-treatment CBCT and LINAC log data with agility multileaf collimator, and SBRT method for centrally located lung tumors in our institution will be shown. In our institution, these efforts have been made with the goal of raising the local control rate and decreasing adverse effects after SBRT.

Show MeSH
Related in: MedlinePlus