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Stereotactic body radiotherapy for small lung tumors in the University of Tokyo Hospital.

Yamashita H, Takahashi W, Haga A, Kida S, Saotome N, Nakagawa K - Biomed Res Int (2014)

Bottom Line: Our work on stereotactic body radiation therapy (SBRT) for primary and metastatic lung tumors will be described.The eligibility criteria for SBRT, our previous SBRT method, the definition of target volume, heterogeneity correction, the position adjustment using four-dimensional cone-beam computed tomography (4D CBCT) immediately before SBRT, volumetric modulated arc therapy (VMAT) method for SBRT, verifying of tumor position within internal target volume (ITV) using in-treatment 4D-CBCT during VMAT-SBRT, shortening of treatment time using flattening-filter-free (FFF) techniques, delivery of 4D dose calculation for lung-VMAT patients using in-treatment CBCT and LINAC log data with agility multileaf collimator, and SBRT method for centrally located lung tumors in our institution will be shown.In our institution, these efforts have been made with the goal of raising the local control rate and decreasing adverse effects after SBRT.

View Article: PubMed Central - PubMed

Affiliation: Department of Radiology, The University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan.

ABSTRACT
Our work on stereotactic body radiation therapy (SBRT) for primary and metastatic lung tumors will be described. The eligibility criteria for SBRT, our previous SBRT method, the definition of target volume, heterogeneity correction, the position adjustment using four-dimensional cone-beam computed tomography (4D CBCT) immediately before SBRT, volumetric modulated arc therapy (VMAT) method for SBRT, verifying of tumor position within internal target volume (ITV) using in-treatment 4D-CBCT during VMAT-SBRT, shortening of treatment time using flattening-filter-free (FFF) techniques, delivery of 4D dose calculation for lung-VMAT patients using in-treatment CBCT and LINAC log data with agility multileaf collimator, and SBRT method for centrally located lung tumors in our institution will be shown. In our institution, these efforts have been made with the goal of raising the local control rate and decreasing adverse effects after SBRT.

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4D CBCT images on the first day overlaid with PTV (in sky blue) and ITV (in yellow) contours after lung tumor registration for five consecutive respiratory phases covering half a breathing cycle, where the tumor moves from cranial to caudal direction during the half cycle [9].
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fig2: 4D CBCT images on the first day overlaid with PTV (in sky blue) and ITV (in yellow) contours after lung tumor registration for five consecutive respiratory phases covering half a breathing cycle, where the tumor moves from cranial to caudal direction during the half cycle [9].

Mentions: Three-dimensional (3D) “volumetric” imaging using CT mounted on the LINAC represents the latest development in the IGRT armamentaria [40]. Cone-beam CT (CBCT) imaging involves multiple kilovolt (kV) radiographs acquired by a large flat-panel detector [41–43]. The 4D CBCT was also extended by sorting kV radiograph images from the patient's respiratory signals before reconstruction [44, 45]. With the 3D or 4D information obtained just prior to treatment, the patient location can be corrected remotely by controlling the treatment couch, and the treatment can be quickly started. We showed 4D CBCT images overlaid with PTV and ITV contours after lung tumor registration for five consecutive respiratory phases covering half a breathing cycle in Figure 2.


Stereotactic body radiotherapy for small lung tumors in the University of Tokyo Hospital.

Yamashita H, Takahashi W, Haga A, Kida S, Saotome N, Nakagawa K - Biomed Res Int (2014)

4D CBCT images on the first day overlaid with PTV (in sky blue) and ITV (in yellow) contours after lung tumor registration for five consecutive respiratory phases covering half a breathing cycle, where the tumor moves from cranial to caudal direction during the half cycle [9].
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4109604&req=5

fig2: 4D CBCT images on the first day overlaid with PTV (in sky blue) and ITV (in yellow) contours after lung tumor registration for five consecutive respiratory phases covering half a breathing cycle, where the tumor moves from cranial to caudal direction during the half cycle [9].
Mentions: Three-dimensional (3D) “volumetric” imaging using CT mounted on the LINAC represents the latest development in the IGRT armamentaria [40]. Cone-beam CT (CBCT) imaging involves multiple kilovolt (kV) radiographs acquired by a large flat-panel detector [41–43]. The 4D CBCT was also extended by sorting kV radiograph images from the patient's respiratory signals before reconstruction [44, 45]. With the 3D or 4D information obtained just prior to treatment, the patient location can be corrected remotely by controlling the treatment couch, and the treatment can be quickly started. We showed 4D CBCT images overlaid with PTV and ITV contours after lung tumor registration for five consecutive respiratory phases covering half a breathing cycle in Figure 2.

Bottom Line: Our work on stereotactic body radiation therapy (SBRT) for primary and metastatic lung tumors will be described.The eligibility criteria for SBRT, our previous SBRT method, the definition of target volume, heterogeneity correction, the position adjustment using four-dimensional cone-beam computed tomography (4D CBCT) immediately before SBRT, volumetric modulated arc therapy (VMAT) method for SBRT, verifying of tumor position within internal target volume (ITV) using in-treatment 4D-CBCT during VMAT-SBRT, shortening of treatment time using flattening-filter-free (FFF) techniques, delivery of 4D dose calculation for lung-VMAT patients using in-treatment CBCT and LINAC log data with agility multileaf collimator, and SBRT method for centrally located lung tumors in our institution will be shown.In our institution, these efforts have been made with the goal of raising the local control rate and decreasing adverse effects after SBRT.

View Article: PubMed Central - PubMed

Affiliation: Department of Radiology, The University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan.

ABSTRACT
Our work on stereotactic body radiation therapy (SBRT) for primary and metastatic lung tumors will be described. The eligibility criteria for SBRT, our previous SBRT method, the definition of target volume, heterogeneity correction, the position adjustment using four-dimensional cone-beam computed tomography (4D CBCT) immediately before SBRT, volumetric modulated arc therapy (VMAT) method for SBRT, verifying of tumor position within internal target volume (ITV) using in-treatment 4D-CBCT during VMAT-SBRT, shortening of treatment time using flattening-filter-free (FFF) techniques, delivery of 4D dose calculation for lung-VMAT patients using in-treatment CBCT and LINAC log data with agility multileaf collimator, and SBRT method for centrally located lung tumors in our institution will be shown. In our institution, these efforts have been made with the goal of raising the local control rate and decreasing adverse effects after SBRT.

Show MeSH
Related in: MedlinePlus