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Sarcoidosis incidentally diagnosed: a case report.

Kesici B, Toros AB, Bayraktar L, Dervisoglu A - Case Rep Pulmonol (2014)

Bottom Line: Sarcoidosis is a chronic, granulomatous condition with unknown cause.Because most of the patients are free of clinical symptoms, sarcoidosis should be considered in differential diagnosis if noncaseous granuloma is noted in biopsies, performed for other reasons.With no clinical symptoms, our patient was diagnosed with sarcoidosis upon identifying noncaseous granuloma in the lymph node biopsy material collected during the laparoscopic operation, performed for gallbladder polyp.

View Article: PubMed Central - PubMed

Affiliation: Department of Gastroenterohepatology, Medical Faculty Bahcesehir University, Istanbul, Turkey.

ABSTRACT
Sarcoidosis is a chronic, granulomatous condition with unknown cause. Because most of the patients are free of clinical symptoms, sarcoidosis should be considered in differential diagnosis if noncaseous granuloma is noted in biopsies, performed for other reasons. With no clinical symptoms, our patient was diagnosed with sarcoidosis upon identifying noncaseous granuloma in the lymph node biopsy material collected during the laparoscopic operation, performed for gallbladder polyp.

No MeSH data available.


Related in: MedlinePlus

Thoracic CT views.
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Related In: Results  -  Collection


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fig4: Thoracic CT views.

Mentions: The 20-year-old female patient presented with abdominal pain, which began 10 days ago, and underwent relevant examinations, among which abdominal USG demonstrated a polypoid lesion with a diameter of 5.7 mm in the gallbladder, and laparoscopic cholecystectomy was therefore performed. Plaques, white in color, on the liver were noted during the surgery, although biopsy material was not collected, due to the risk of bleeding. The patient was referred to our clinic when chronic cholecystitis and nonnecrotizing granulomatous lymphadenitis in one lymph node were identified in the sections. Patient's investigations yielded normal hepatic enzymes; HBsAg and AntiHCV were negative. PA chest X-ray demonstrated fullness at both hili. Thoracic CT was performed (Figures 2, 3, 4, and 5) and was reported as upper mediastinal-bilateral superior and inferior paratracheal-aortopulmonary-paraesophageal-subcranial LAMs, the largest of which has a diameter of up to 13 mm, are observed. Pleuroparenchymal sequelae densities are present in the apical lobe of bilateral lungs. Centrilobular nodules are observed at bilateral lungs. There are celiac-periportal LAMs in the section crossing the upper abdomen. The findings reported principally suggest sarcoidosis. Patient's biopsies were therefore reevaluated at the pathology clinic of the university hospital. Nonnecrotizing granulomatous lymphadenitis was identified at the lymph node. The findings suggested sarcoidosis. Increased levels of angiotensin-converting enzyme (ACE) were found (197,5 U/L; normal range: 8–52). Calcium level was normal.


Sarcoidosis incidentally diagnosed: a case report.

Kesici B, Toros AB, Bayraktar L, Dervisoglu A - Case Rep Pulmonol (2014)

Thoracic CT views.
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4109602&req=5

fig4: Thoracic CT views.
Mentions: The 20-year-old female patient presented with abdominal pain, which began 10 days ago, and underwent relevant examinations, among which abdominal USG demonstrated a polypoid lesion with a diameter of 5.7 mm in the gallbladder, and laparoscopic cholecystectomy was therefore performed. Plaques, white in color, on the liver were noted during the surgery, although biopsy material was not collected, due to the risk of bleeding. The patient was referred to our clinic when chronic cholecystitis and nonnecrotizing granulomatous lymphadenitis in one lymph node were identified in the sections. Patient's investigations yielded normal hepatic enzymes; HBsAg and AntiHCV were negative. PA chest X-ray demonstrated fullness at both hili. Thoracic CT was performed (Figures 2, 3, 4, and 5) and was reported as upper mediastinal-bilateral superior and inferior paratracheal-aortopulmonary-paraesophageal-subcranial LAMs, the largest of which has a diameter of up to 13 mm, are observed. Pleuroparenchymal sequelae densities are present in the apical lobe of bilateral lungs. Centrilobular nodules are observed at bilateral lungs. There are celiac-periportal LAMs in the section crossing the upper abdomen. The findings reported principally suggest sarcoidosis. Patient's biopsies were therefore reevaluated at the pathology clinic of the university hospital. Nonnecrotizing granulomatous lymphadenitis was identified at the lymph node. The findings suggested sarcoidosis. Increased levels of angiotensin-converting enzyme (ACE) were found (197,5 U/L; normal range: 8–52). Calcium level was normal.

Bottom Line: Sarcoidosis is a chronic, granulomatous condition with unknown cause.Because most of the patients are free of clinical symptoms, sarcoidosis should be considered in differential diagnosis if noncaseous granuloma is noted in biopsies, performed for other reasons.With no clinical symptoms, our patient was diagnosed with sarcoidosis upon identifying noncaseous granuloma in the lymph node biopsy material collected during the laparoscopic operation, performed for gallbladder polyp.

View Article: PubMed Central - PubMed

Affiliation: Department of Gastroenterohepatology, Medical Faculty Bahcesehir University, Istanbul, Turkey.

ABSTRACT
Sarcoidosis is a chronic, granulomatous condition with unknown cause. Because most of the patients are free of clinical symptoms, sarcoidosis should be considered in differential diagnosis if noncaseous granuloma is noted in biopsies, performed for other reasons. With no clinical symptoms, our patient was diagnosed with sarcoidosis upon identifying noncaseous granuloma in the lymph node biopsy material collected during the laparoscopic operation, performed for gallbladder polyp.

No MeSH data available.


Related in: MedlinePlus