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Abdominal obesity is associated with heart disease in dogs.

Thengchaisri N, Theerapun W, Kaewmokul S, Sastravaha A - BMC Vet. Res. (2014)

Bottom Line: The following morphometric measurements were greater in the heart disease group compared with healthy canines: MBMI (65.0 ± 4.5 vs. 52.5 ± 3.7 kg/m2, respectively, P = 0.035); WIWDR (4.1 ± 0.1 vs. 3.1 ± 0.1, P < 0.01); and WTLR (1.25 ± 0.04 vs. 1.05 ± 0.04, P < 0.01).However, there was no significant difference in WHSDR (3.6 ± 0.1 vs. 3.7 ± 0.2, P = 0.875).Our data indicate that abdominal obesity, rather than overall obesity, is associated with heart disease in dogs.

View Article: PubMed Central - HTML - PubMed

Affiliation: Department of Companion Animal Clinical Sciences, Faculty of Veterinary Medicine, Kasetsart University, 50 Pahonyothin Rd,, Lat Yao, Chatuchak, Bangkok 10900, Thailand. ajnaris@yahoo.com.

ABSTRACT

Background: The relationship between overall obesity and fat distribution in dogs and the development of heart disease is unclear. In the present study we evaluated the association between overall obesity and fat distribution and clinical heart disease by morphometric and computed tomography (CT)-based measurements. Body condition score (BCS), modified body mass index (MBMI, kg/m2), waist-to-hock-to-stifle distance ratio (WHSDR), waist-to-ilium wing distance ratio (WIWDR), and waist-to-truncal length ratio (WTLR) were compared between dogs with (n = 44) and without (n = 43) heart disease using receiver operating characteristic (ROC) analysis. Intra-abdominal fat (IAF) and subcutaneous fat (SQF) were measured in dogs with (n = 8) and without (n = 9) heart disease at the center of the fourth and fifth lumbar vertebrae by CT.

Results: BCS was similar between heart disease and healthy groups (3.6 ± 0.2 vs. 3.3 ± 0.1, P = 0.126). The following morphometric measurements were greater in the heart disease group compared with healthy canines: MBMI (65.0 ± 4.5 vs. 52.5 ± 3.7 kg/m2, respectively, P = 0.035); WIWDR (4.1 ± 0.1 vs. 3.1 ± 0.1, P < 0.01); and WTLR (1.25 ± 0.04 vs. 1.05 ± 0.04, P < 0.01). However, there was no significant difference in WHSDR (3.6 ± 0.1 vs. 3.7 ± 0.2, P = 0.875). Interestingly, IAF was significantly increased in dogs with heart disease compared with healthy dogs (23.5 ± 1.5% vs. 19.4 ± 1.2%, P = 0.039) whereas SQF was similar between two groups (35.5 ± 2.7% vs. 38.6 ± 3.5%, P = 0.496). Of the five morphometric indices studied, WIWDR and WTLR provided acceptable discrimination for diagnosing heart disease in dogs, with areas under the ROC curve of 0.778 (95% confidence interval [CI]:0.683-0.874) and 0.727 (95% CI:0.619-0.835), respectively.

Conclusions: Our data indicate that abdominal obesity, rather than overall obesity, is associated with heart disease in dogs. Measurements of both WIWDR and WTLR are particular useful for detection of an abdominal obesity in dogs.

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Average body condition score (mean ± SE) of male and female dogs from healthy and heart disease groups.
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Figure 1: Average body condition score (mean ± SE) of male and female dogs from healthy and heart disease groups.

Mentions: The average BCS in the heart disease group was slightly higher than that in the healthy group but the difference was not significant (3.6 ± 0.2 vs. 3.3 ± 0.1, P = 0.126). There was also no significant difference in BCS between heart disease and healthy groups when animals were analyzed according to gender: 3.4 ± 0.2 vs. 3.2 ± 0.2 (P = 0.4293) for males and 3.8 ± 0.2 vs. 3.3 ± 0.2 (P = 0.701) for females (Figure 1). The average MBMI in the heart disease group was significantly higher than that in healthy animals (65.0 ± 4.5 vs. 52.5 ± 3.7 kg/m2; P = 0.035) (Table 1).


Abdominal obesity is associated with heart disease in dogs.

Thengchaisri N, Theerapun W, Kaewmokul S, Sastravaha A - BMC Vet. Res. (2014)

Average body condition score (mean ± SE) of male and female dogs from healthy and heart disease groups.
© Copyright Policy - open-access
Related In: Results  -  Collection

License 1 - License 2
Show All Figures
getmorefigures.php?uid=PMC4066699&req=5

Figure 1: Average body condition score (mean ± SE) of male and female dogs from healthy and heart disease groups.
Mentions: The average BCS in the heart disease group was slightly higher than that in the healthy group but the difference was not significant (3.6 ± 0.2 vs. 3.3 ± 0.1, P = 0.126). There was also no significant difference in BCS between heart disease and healthy groups when animals were analyzed according to gender: 3.4 ± 0.2 vs. 3.2 ± 0.2 (P = 0.4293) for males and 3.8 ± 0.2 vs. 3.3 ± 0.2 (P = 0.701) for females (Figure 1). The average MBMI in the heart disease group was significantly higher than that in healthy animals (65.0 ± 4.5 vs. 52.5 ± 3.7 kg/m2; P = 0.035) (Table 1).

Bottom Line: The following morphometric measurements were greater in the heart disease group compared with healthy canines: MBMI (65.0 ± 4.5 vs. 52.5 ± 3.7 kg/m2, respectively, P = 0.035); WIWDR (4.1 ± 0.1 vs. 3.1 ± 0.1, P < 0.01); and WTLR (1.25 ± 0.04 vs. 1.05 ± 0.04, P < 0.01).However, there was no significant difference in WHSDR (3.6 ± 0.1 vs. 3.7 ± 0.2, P = 0.875).Our data indicate that abdominal obesity, rather than overall obesity, is associated with heart disease in dogs.

View Article: PubMed Central - HTML - PubMed

Affiliation: Department of Companion Animal Clinical Sciences, Faculty of Veterinary Medicine, Kasetsart University, 50 Pahonyothin Rd,, Lat Yao, Chatuchak, Bangkok 10900, Thailand. ajnaris@yahoo.com.

ABSTRACT

Background: The relationship between overall obesity and fat distribution in dogs and the development of heart disease is unclear. In the present study we evaluated the association between overall obesity and fat distribution and clinical heart disease by morphometric and computed tomography (CT)-based measurements. Body condition score (BCS), modified body mass index (MBMI, kg/m2), waist-to-hock-to-stifle distance ratio (WHSDR), waist-to-ilium wing distance ratio (WIWDR), and waist-to-truncal length ratio (WTLR) were compared between dogs with (n = 44) and without (n = 43) heart disease using receiver operating characteristic (ROC) analysis. Intra-abdominal fat (IAF) and subcutaneous fat (SQF) were measured in dogs with (n = 8) and without (n = 9) heart disease at the center of the fourth and fifth lumbar vertebrae by CT.

Results: BCS was similar between heart disease and healthy groups (3.6 ± 0.2 vs. 3.3 ± 0.1, P = 0.126). The following morphometric measurements were greater in the heart disease group compared with healthy canines: MBMI (65.0 ± 4.5 vs. 52.5 ± 3.7 kg/m2, respectively, P = 0.035); WIWDR (4.1 ± 0.1 vs. 3.1 ± 0.1, P < 0.01); and WTLR (1.25 ± 0.04 vs. 1.05 ± 0.04, P < 0.01). However, there was no significant difference in WHSDR (3.6 ± 0.1 vs. 3.7 ± 0.2, P = 0.875). Interestingly, IAF was significantly increased in dogs with heart disease compared with healthy dogs (23.5 ± 1.5% vs. 19.4 ± 1.2%, P = 0.039) whereas SQF was similar between two groups (35.5 ± 2.7% vs. 38.6 ± 3.5%, P = 0.496). Of the five morphometric indices studied, WIWDR and WTLR provided acceptable discrimination for diagnosing heart disease in dogs, with areas under the ROC curve of 0.778 (95% confidence interval [CI]:0.683-0.874) and 0.727 (95% CI:0.619-0.835), respectively.

Conclusions: Our data indicate that abdominal obesity, rather than overall obesity, is associated with heart disease in dogs. Measurements of both WIWDR and WTLR are particular useful for detection of an abdominal obesity in dogs.

Show MeSH
Related in: MedlinePlus