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Genome rearrangements and pervasive meiotic drive cause hybrid infertility in fission yeast.

Zanders SE, Eickbush MT, Yu JS, Kang JW, Fowler KR, Smith GR, Malik HS - Elife (2014)

Bottom Line: Hybrid sterility is one of the earliest postzygotic isolating mechanisms to evolve between two recently diverged species.Two of these driving loci are linked by a chromosomal translocation and thus constitute a novel type of paired meiotic drive complex.Our study reveals how quickly multiple barriers to fertility can arise.

View Article: PubMed Central - PubMed

Affiliation: Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, United States.

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Related in: MedlinePlus

DSB hotspots in Sk and Sp.We used ChIP-chip of Rec12-FLAG from rad50S Sk meiotic cultures to assay DSB hotspots and compared the Sk profile (red) to the published DSB hotspot maps of Sp (black) (Fowler et al., 2013). Traces are shown in Figure 2—figure supplements 1–11.DOI:http://dx.doi.org/10.7554/eLife.02630.007
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fig2s3: DSB hotspots in Sk and Sp.We used ChIP-chip of Rec12-FLAG from rad50S Sk meiotic cultures to assay DSB hotspots and compared the Sk profile (red) to the published DSB hotspot maps of Sp (black) (Fowler et al., 2013). Traces are shown in Figure 2—figure supplements 1–11.DOI:http://dx.doi.org/10.7554/eLife.02630.007


Genome rearrangements and pervasive meiotic drive cause hybrid infertility in fission yeast.

Zanders SE, Eickbush MT, Yu JS, Kang JW, Fowler KR, Smith GR, Malik HS - Elife (2014)

DSB hotspots in Sk and Sp.We used ChIP-chip of Rec12-FLAG from rad50S Sk meiotic cultures to assay DSB hotspots and compared the Sk profile (red) to the published DSB hotspot maps of Sp (black) (Fowler et al., 2013). Traces are shown in Figure 2—figure supplements 1–11.DOI:http://dx.doi.org/10.7554/eLife.02630.007
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4066438&req=5

fig2s3: DSB hotspots in Sk and Sp.We used ChIP-chip of Rec12-FLAG from rad50S Sk meiotic cultures to assay DSB hotspots and compared the Sk profile (red) to the published DSB hotspot maps of Sp (black) (Fowler et al., 2013). Traces are shown in Figure 2—figure supplements 1–11.DOI:http://dx.doi.org/10.7554/eLife.02630.007
Bottom Line: Hybrid sterility is one of the earliest postzygotic isolating mechanisms to evolve between two recently diverged species.Two of these driving loci are linked by a chromosomal translocation and thus constitute a novel type of paired meiotic drive complex.Our study reveals how quickly multiple barriers to fertility can arise.

View Article: PubMed Central - PubMed

Affiliation: Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, United States.

Show MeSH
Related in: MedlinePlus