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Collagen cross-linking in the treatment of pellucid marginal degeneration.

Hassan Z, Nemeth G, Modis L, Szalai E, Berta A - Indian J Ophthalmol (2014)

Bottom Line: Uncorrected, LogMAR visual acuity has improved from +0.8 to +0.55 during the 6 months and +0.3 during the 8 months follow-up after CXL.Keratometric values and topografic indexes disclosed no progression of the disease.CXL may postpone or eliminate the need of corneal transplantation in cases with PMD.

View Article: PubMed Central - PubMed

Affiliation: Orbident Refractive Surgery and Medical Center, University of Debrecen, Debrecen, Hungary.

ABSTRACT
Pellucid marginal degeneration (PMD) is an uncommon cause of inferior peripheral corneal thinning disorder, characterized by irregular astigmatism. We analyzed a case of bilateral PMD patient and treated one eye with corneal collagen cross-linking (CXL) therapy. Corneal topography was characteristic for PMD. Visual acuity, slitlamp examinations, tonometry, and corneal thickness were observed. Simulated keratometric and topographic index values were detected with corneal topography. Uncorrected, LogMAR visual acuity has improved from +0.8 to +0.55 during the 6 months and +0.3 during the 8 months follow-up after CXL. Pachymetry values and intraocular pressure showed no changes. Keratometric values and topografic indexes disclosed no progression of the disease. CXL may postpone or eliminate the need of corneal transplantation in cases with PMD.

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Corneal topograph shows flattening of the inferior cornea 8 months after CXL treatment
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Figure 4: Corneal topograph shows flattening of the inferior cornea 8 months after CXL treatment

Mentions: The follow-up period was 8 months. Visual acuity, simulated keratometric indexes, and corneal thickness values were detected during the postoperative period. Uncorrected visual acuity has increased from +0.8 to +0.55; best-corrected visual acuity was +0.25 with a correction of spherical equivalent of -4.0 D 8 months after CXL treatment. After CXL treatment, SK1 decreased to 50.48 D and SK2 to 33.97 D [Fig. 4]. Pre- and postoperative corneal back surface Scheimpflug pictures (Pentacam HR) do not show difference [Fig. 5].


Collagen cross-linking in the treatment of pellucid marginal degeneration.

Hassan Z, Nemeth G, Modis L, Szalai E, Berta A - Indian J Ophthalmol (2014)

Corneal topograph shows flattening of the inferior cornea 8 months after CXL treatment
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4061688&req=5

Figure 4: Corneal topograph shows flattening of the inferior cornea 8 months after CXL treatment
Mentions: The follow-up period was 8 months. Visual acuity, simulated keratometric indexes, and corneal thickness values were detected during the postoperative period. Uncorrected visual acuity has increased from +0.8 to +0.55; best-corrected visual acuity was +0.25 with a correction of spherical equivalent of -4.0 D 8 months after CXL treatment. After CXL treatment, SK1 decreased to 50.48 D and SK2 to 33.97 D [Fig. 4]. Pre- and postoperative corneal back surface Scheimpflug pictures (Pentacam HR) do not show difference [Fig. 5].

Bottom Line: Uncorrected, LogMAR visual acuity has improved from +0.8 to +0.55 during the 6 months and +0.3 during the 8 months follow-up after CXL.Keratometric values and topografic indexes disclosed no progression of the disease.CXL may postpone or eliminate the need of corneal transplantation in cases with PMD.

View Article: PubMed Central - PubMed

Affiliation: Orbident Refractive Surgery and Medical Center, University of Debrecen, Debrecen, Hungary.

ABSTRACT
Pellucid marginal degeneration (PMD) is an uncommon cause of inferior peripheral corneal thinning disorder, characterized by irregular astigmatism. We analyzed a case of bilateral PMD patient and treated one eye with corneal collagen cross-linking (CXL) therapy. Corneal topography was characteristic for PMD. Visual acuity, slitlamp examinations, tonometry, and corneal thickness were observed. Simulated keratometric and topographic index values were detected with corneal topography. Uncorrected, LogMAR visual acuity has improved from +0.8 to +0.55 during the 6 months and +0.3 during the 8 months follow-up after CXL. Pachymetry values and intraocular pressure showed no changes. Keratometric values and topografic indexes disclosed no progression of the disease. CXL may postpone or eliminate the need of corneal transplantation in cases with PMD.

Show MeSH
Related in: MedlinePlus