Preoperative corneal topographic picture of the right e

Collagen cross-linking in the treatment of pellucid marginal degeneration. Hassan Z, Nemeth G, Modis L, Szalai E, Berta A - Indian J Ophthalmol (2014) Bottom Line: Uncorrected, LogMAR visual acuity has improved from +0.8 to +0.55 during the 6 months and +0.3 during the 8 months follow-up after CXL.Keratometric values and topografic indexes disclosed no progression of the disease.CXL may postpone or eliminate the need of corneal transplantation in cases with PMD. View Article: PubMed Central - PubMed Affiliation: Orbident Refractive Surgery and Medical Center, University of Debrecen, Debrecen, Hungary. ABSTRACT Pellucid marginal degeneration (PMD) is an uncommon cause of inferior peripheral corneal thinning disorder, characterized by irregular astigmatism. We analyzed a case of bilateral PMD patient and treated one eye with corneal collagen cross-linking (CXL) therapy. Corneal topography was characteristic for PMD. Visual acuity, slitlamp examinations, tonometry, and corneal thickness were observed. Simulated keratometric and topographic index values were detected with corneal topography. Uncorrected, LogMAR visual acuity has improved from +0.8 to +0.55 during the 6 months and +0.3 during the 8 months follow-up after CXL. Pachymetry values and intraocular pressure showed no changes. Keratometric values and topografic indexes disclosed no progression of the disease. CXL may postpone or eliminate the need of corneal transplantation in cases with PMD. Show MeSH Major Collagen/therapeutic use* Corneal Dystrophies, Hereditary/diagnosis/drug therapy* Corneal Stroma/pathology* Minor Corneal Topography Cross-Linking Reagents/therapeutic use Humans Male Middle Aged Photochemotherapy Photosensitizing Agents/therapeutic use Visual Acuity Related in: MedlinePlus	© Copyright Policy - open-access Related In: Results - Collection License Show All Figures getmorefigures.php?uid=PMC4061688&req=5 Figure 3: Preoperative corneal topographic picture of the right eye shows the characteristic bow-tie appearance of corneal steepening (red zones) and midperipheral inferior corneal flattening Mentions: Corneal topography was characteristic for PMD. The vertical axis images showed significant central irregular against-the-rule astigmatism, marked peripheral thinning within 2.0 mm of the limbus, and more normal corneal thickness inferior to the band of thinning. Topograph sagittal curvature map on the right eye showed vertical flatting and irregular inferior corneal astigmatism. The horizontal axis had more normal corneal contour and thickness. Keratometric readings were 53.98D/36.04D in the right eye. In both eyes, there was a bow-tie-shaped corneal astigmatism with a value of 17.96D in the right eye [Fig. 3]. This clinical picture was consistent with a diagnosis of PMD of both eyes.

Collagen cross-linking in the treatment of pellucid marginal degeneration.

Hassan Z, Nemeth G, Modis L, Szalai E, Berta A - Indian J Ophthalmol (2014)

Bottom Line: Uncorrected, LogMAR visual acuity has improved from +0.8 to +0.55 during the 6 months and +0.3 during the 8 months follow-up after CXL.Keratometric values and topografic indexes disclosed no progression of the disease.CXL may postpone or eliminate the need of corneal transplantation in cases with PMD.

View Article: PubMed Central - PubMed

Affiliation: Orbident Refractive Surgery and Medical Center, University of Debrecen, Debrecen, Hungary.

ABSTRACT

Pellucid marginal degeneration (PMD) is an uncommon cause of inferior peripheral corneal thinning disorder, characterized by irregular astigmatism. We analyzed a case of bilateral PMD patient and treated one eye with corneal collagen cross-linking (CXL) therapy. Corneal topography was characteristic for PMD. Visual acuity, slitlamp examinations, tonometry, and corneal thickness were observed. Simulated keratometric and topographic index values were detected with corneal topography. Uncorrected, LogMAR visual acuity has improved from +0.8 to +0.55 during the 6 months and +0.3 during the 8 months follow-up after CXL. Pachymetry values and intraocular pressure showed no changes. Keratometric values and topografic indexes disclosed no progression of the disease. CXL may postpone or eliminate the need of corneal transplantation in cases with PMD.

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Related in: MedlinePlus

Preoperative corneal topographic picture of the right eye shows the characteristic bow-tie appearance of corneal steepening (red zones) and midperipheral inferior corneal flattening

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Figure 3: Preoperative corneal topographic picture of the right eye shows the characteristic bow-tie appearance of corneal steepening (red zones) and midperipheral inferior corneal flattening

Mentions: Corneal topography was characteristic for PMD. The vertical axis images showed significant central irregular against-the-rule astigmatism, marked peripheral thinning within 2.0 mm of the limbus, and more normal corneal thickness inferior to the band of thinning. Topograph sagittal curvature map on the right eye showed vertical flatting and irregular inferior corneal astigmatism. The horizontal axis had more normal corneal contour and thickness. Keratometric readings were 53.98D/36.04D in the right eye. In both eyes, there was a bow-tie-shaped corneal astigmatism with a value of 17.96D in the right eye [Fig. 3]. This clinical picture was consistent with a diagnosis of PMD of both eyes.