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Annular elastolytic giant cell granuloma of conjunctiva: a case report.

Konar K, Sanyal S, Rakshit A - Indian J Ophthalmol (2014)

Bottom Line: All the previous patients were females with lesions in nasal or temporal bulbar conjunctiva varying 2-3 mm in size.We report a male patient aged 70 years presenting with a 14 mm × 7 mm fleshy mass on right lower bulbar conjunctiva.Clinical differential diagnoses were lymphoma, squamous cell carcinoma in situ and amyloidosis.

View Article: PubMed Central - PubMed

Affiliation: Department of Pathology, Burdwan Medical College, Burdwan, West Bengal, India.

ABSTRACT
Annular elastolytic giant cell granuloma is a condition characterized histologically by damaged elastic fibers associated with preponderance of giant cells along with absence of necrobiosis, lipid, mucin, and pallisading granuloma. It usually occurs on sun-damaged skin and hence the previous name actinic granuloma. A similar process occurs on the conjunctiva. Over the past three decades only four cases of conjunctival actinic granuloma have been documented. All the previous patients were females with lesions in nasal or temporal bulbar conjunctiva varying 2-3 mm in size. We report a male patient aged 70 years presenting with a 14 mm × 7 mm fleshy mass on right lower bulbar conjunctiva. Clinical differential diagnoses were lymphoma, squamous cell carcinoma in situ and amyloidosis. Surgical excision followed by histopathology confirmed it to be a case of actinic granuloma. This is the first case of isolated conjunctival actinic granuloma of such a large size reported from India.

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Clinical photograph showing 14 mm × 7 mm red fleshy mass in right lower bulbar conjunctiva
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Figure 1: Clinical photograph showing 14 mm × 7 mm red fleshy mass in right lower bulbar conjunctiva

Mentions: Ocular examination revealed a 14 mm × 7 mm red fleshy mass in the lower bulbar conjunctiva in the right eye [Fig. 1]. Vision in the right eye was 20/100 with early cataractous change. The left eye was pseudophakic and had a total retinal detachment with only PL. The patient had no significant past medical history.


Annular elastolytic giant cell granuloma of conjunctiva: a case report.

Konar K, Sanyal S, Rakshit A - Indian J Ophthalmol (2014)

Clinical photograph showing 14 mm × 7 mm red fleshy mass in right lower bulbar conjunctiva
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4061685&req=5

Figure 1: Clinical photograph showing 14 mm × 7 mm red fleshy mass in right lower bulbar conjunctiva
Mentions: Ocular examination revealed a 14 mm × 7 mm red fleshy mass in the lower bulbar conjunctiva in the right eye [Fig. 1]. Vision in the right eye was 20/100 with early cataractous change. The left eye was pseudophakic and had a total retinal detachment with only PL. The patient had no significant past medical history.

Bottom Line: All the previous patients were females with lesions in nasal or temporal bulbar conjunctiva varying 2-3 mm in size.We report a male patient aged 70 years presenting with a 14 mm × 7 mm fleshy mass on right lower bulbar conjunctiva.Clinical differential diagnoses were lymphoma, squamous cell carcinoma in situ and amyloidosis.

View Article: PubMed Central - PubMed

Affiliation: Department of Pathology, Burdwan Medical College, Burdwan, West Bengal, India.

ABSTRACT
Annular elastolytic giant cell granuloma is a condition characterized histologically by damaged elastic fibers associated with preponderance of giant cells along with absence of necrobiosis, lipid, mucin, and pallisading granuloma. It usually occurs on sun-damaged skin and hence the previous name actinic granuloma. A similar process occurs on the conjunctiva. Over the past three decades only four cases of conjunctival actinic granuloma have been documented. All the previous patients were females with lesions in nasal or temporal bulbar conjunctiva varying 2-3 mm in size. We report a male patient aged 70 years presenting with a 14 mm × 7 mm fleshy mass on right lower bulbar conjunctiva. Clinical differential diagnoses were lymphoma, squamous cell carcinoma in situ and amyloidosis. Surgical excision followed by histopathology confirmed it to be a case of actinic granuloma. This is the first case of isolated conjunctival actinic granuloma of such a large size reported from India.

Show MeSH
Related in: MedlinePlus