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Rhodotorula mucilaginosa Keratitis: a rare fungus from Eastern India.

Saha S, Sengupta J, Chatterjee D, Banerjee D - Indian J Ophthalmol (2014)

Bottom Line: Molecular identification of the organism was performed which showed 100% homology with Rhodotorula mucilaginosa.Management of these cases is difficult often necessitating surgical procedures.However further reports are necessary to understand the disease and establish a treatment protocol.

View Article: PubMed Central - PubMed

Affiliation: Ocular Microbiology Laboratory Services, Priyamvada Birla Aravind Eye Hospital, 10 Loudon Street, Kolkata; Department of Microbiology, Vidyasagar University, Midnapore, India.

ABSTRACT
Rhodotorula mucilaginosa rarely cause keratitis in immunocompromised individuals. A 30 year old male with history of minor trauma presented with cotton wool like stromal infiltration and hypopyon in left eye. Microbiological examination of corneal scraping showed fungal hyphae and yeast cells in direct smear. Molecular identification of the organism was performed which showed 100% homology with Rhodotorula mucilaginosa. Management of these cases is difficult often necessitating surgical procedures. However further reports are necessary to understand the disease and establish a treatment protocol.

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Chromatograme data with both primer with Gel image of PCR amplicon
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Figure 6: Chromatograme data with both primer with Gel image of PCR amplicon

Mentions: Species confirmation was carried out at the Xcelris Genomic Centre, Ahmedabad, India by using D1/D2 region of LSU (Large SubUnit: 28SrDNA) based on PCR technique. PCR amplified a band with a sequence that was 100% homologous with Rhodotorula mucilaginosa (strain IMUFRJ 52028/ Gen Bank Accession Number: FN428899.1) [Fig. 6].


Rhodotorula mucilaginosa Keratitis: a rare fungus from Eastern India.

Saha S, Sengupta J, Chatterjee D, Banerjee D - Indian J Ophthalmol (2014)

Chromatograme data with both primer with Gel image of PCR amplicon
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4061676&req=5

Figure 6: Chromatograme data with both primer with Gel image of PCR amplicon
Mentions: Species confirmation was carried out at the Xcelris Genomic Centre, Ahmedabad, India by using D1/D2 region of LSU (Large SubUnit: 28SrDNA) based on PCR technique. PCR amplified a band with a sequence that was 100% homologous with Rhodotorula mucilaginosa (strain IMUFRJ 52028/ Gen Bank Accession Number: FN428899.1) [Fig. 6].

Bottom Line: Molecular identification of the organism was performed which showed 100% homology with Rhodotorula mucilaginosa.Management of these cases is difficult often necessitating surgical procedures.However further reports are necessary to understand the disease and establish a treatment protocol.

View Article: PubMed Central - PubMed

Affiliation: Ocular Microbiology Laboratory Services, Priyamvada Birla Aravind Eye Hospital, 10 Loudon Street, Kolkata; Department of Microbiology, Vidyasagar University, Midnapore, India.

ABSTRACT
Rhodotorula mucilaginosa rarely cause keratitis in immunocompromised individuals. A 30 year old male with history of minor trauma presented with cotton wool like stromal infiltration and hypopyon in left eye. Microbiological examination of corneal scraping showed fungal hyphae and yeast cells in direct smear. Molecular identification of the organism was performed which showed 100% homology with Rhodotorula mucilaginosa. Management of these cases is difficult often necessitating surgical procedures. However further reports are necessary to understand the disease and establish a treatment protocol.

Show MeSH
Related in: MedlinePlus