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A rare case of toxic optic neuropathy secondary to consumption of neem oil.

Suresha AR, Rajesh P, Anil Raj KS, Torgal R - Indian J Ophthalmol (2014)

Bottom Line: Magnetic resonance imaging (MRI) scan showed bilateral putaminal regions with altered signal, hypointensities in T1-weighted images, hyperintensities on T2-weighted, images and hyperintense on Fluid Attenuation Inversion Recovery (FLAIR) images suggestive of cytotoxic edema due to tissue hypoxia.Her vision improved to 20/200 in both eyes with treatment after two months.This is the first case report of such nature in the literature to the best of our knowledge.

View Article: PubMed Central - PubMed

Affiliation: Department of Ophthalmology, J. J. M. Medical College, Davangere, Karnataka, India.

ABSTRACT
A 35-year-old female was referred to our hospital with bilateral loss of vision of two days duration. She gave history of consumption of about 150 ml of neem oil five days back.Examination revealed no perception of light in both eyes. Both pupils were dilated and sluggishly reacting to light. Her fundus examination showed bilateral hyperemic, edematous discs and also edema extending along the superior and inferior temporal vascular arcade. Magnetic resonance imaging (MRI) scan showed bilateral putaminal regions with altered signal, hypointensities in T1-weighted images, hyperintensities on T2-weighted, images and hyperintense on Fluid Attenuation Inversion Recovery (FLAIR) images suggestive of cytotoxic edema due to tissue hypoxia. Her vision improved to 20/200 in both eyes with treatment after two months. This is the first case report of such nature in the literature to the best of our knowledge.

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Related in: MedlinePlus

Left Eye Fundus picture showing reduced disc edema
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Figure 6: Left Eye Fundus picture showing reduced disc edema

Mentions: Patient did not show any visual improvement after one week of treatment but pupillary reactions improved. During her subsequent follow-up after about 15 days her vision in both eyes improved to counting fingers 1/2 meters and at one month follow-up vision was 20/200 in both eyes and pupillary reactions were normal in both eyes. Her fundus examination showed reduced disc edema [Fig. 5 and 6]


A rare case of toxic optic neuropathy secondary to consumption of neem oil.

Suresha AR, Rajesh P, Anil Raj KS, Torgal R - Indian J Ophthalmol (2014)

Left Eye Fundus picture showing reduced disc edema
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4061674&req=5

Figure 6: Left Eye Fundus picture showing reduced disc edema
Mentions: Patient did not show any visual improvement after one week of treatment but pupillary reactions improved. During her subsequent follow-up after about 15 days her vision in both eyes improved to counting fingers 1/2 meters and at one month follow-up vision was 20/200 in both eyes and pupillary reactions were normal in both eyes. Her fundus examination showed reduced disc edema [Fig. 5 and 6]

Bottom Line: Magnetic resonance imaging (MRI) scan showed bilateral putaminal regions with altered signal, hypointensities in T1-weighted images, hyperintensities on T2-weighted, images and hyperintense on Fluid Attenuation Inversion Recovery (FLAIR) images suggestive of cytotoxic edema due to tissue hypoxia.Her vision improved to 20/200 in both eyes with treatment after two months.This is the first case report of such nature in the literature to the best of our knowledge.

View Article: PubMed Central - PubMed

Affiliation: Department of Ophthalmology, J. J. M. Medical College, Davangere, Karnataka, India.

ABSTRACT
A 35-year-old female was referred to our hospital with bilateral loss of vision of two days duration. She gave history of consumption of about 150 ml of neem oil five days back.Examination revealed no perception of light in both eyes. Both pupils were dilated and sluggishly reacting to light. Her fundus examination showed bilateral hyperemic, edematous discs and also edema extending along the superior and inferior temporal vascular arcade. Magnetic resonance imaging (MRI) scan showed bilateral putaminal regions with altered signal, hypointensities in T1-weighted images, hyperintensities on T2-weighted, images and hyperintense on Fluid Attenuation Inversion Recovery (FLAIR) images suggestive of cytotoxic edema due to tissue hypoxia. Her vision improved to 20/200 in both eyes with treatment after two months. This is the first case report of such nature in the literature to the best of our knowledge.

Show MeSH
Related in: MedlinePlus