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A rare case of toxic optic neuropathy secondary to consumption of neem oil.

Suresha AR, Rajesh P, Anil Raj KS, Torgal R - Indian J Ophthalmol (2014)

Bottom Line: Magnetic resonance imaging (MRI) scan showed bilateral putaminal regions with altered signal, hypointensities in T1-weighted images, hyperintensities on T2-weighted, images and hyperintense on Fluid Attenuation Inversion Recovery (FLAIR) images suggestive of cytotoxic edema due to tissue hypoxia.Her vision improved to 20/200 in both eyes with treatment after two months.This is the first case report of such nature in the literature to the best of our knowledge.

View Article: PubMed Central - PubMed

Affiliation: Department of Ophthalmology, J. J. M. Medical College, Davangere, Karnataka, India.

ABSTRACT
A 35-year-old female was referred to our hospital with bilateral loss of vision of two days duration. She gave history of consumption of about 150 ml of neem oil five days back.Examination revealed no perception of light in both eyes. Both pupils were dilated and sluggishly reacting to light. Her fundus examination showed bilateral hyperemic, edematous discs and also edema extending along the superior and inferior temporal vascular arcade. Magnetic resonance imaging (MRI) scan showed bilateral putaminal regions with altered signal, hypointensities in T1-weighted images, hyperintensities on T2-weighted, images and hyperintense on Fluid Attenuation Inversion Recovery (FLAIR) images suggestive of cytotoxic edema due to tissue hypoxia. Her vision improved to 20/200 in both eyes with treatment after two months. This is the first case report of such nature in the literature to the best of our knowledge.

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Bilateral putaminal regions showed altered signal hypointensities in T1W images
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Figure 3: Bilateral putaminal regions showed altered signal hypointensities in T1W images

Mentions: Complete hemogram was within normal limits, Venereal Disease Research Laboratory (VDRL ), HIV1 and 2 were non-reactive. A magnetic resonance imaging (MRI) scan showed bilateral putaminal regions with altered signal, hypointensities in T1-weighted images, hyperintensities on T2-weighted images and hyperintense on Fluid Attenuation Inversion Recovery (FLAIR) images suggestive of cytotoxic edema due to tissue hypoxia [Fig. 3 and 4].


A rare case of toxic optic neuropathy secondary to consumption of neem oil.

Suresha AR, Rajesh P, Anil Raj KS, Torgal R - Indian J Ophthalmol (2014)

Bilateral putaminal regions showed altered signal hypointensities in T1W images
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4061674&req=5

Figure 3: Bilateral putaminal regions showed altered signal hypointensities in T1W images
Mentions: Complete hemogram was within normal limits, Venereal Disease Research Laboratory (VDRL ), HIV1 and 2 were non-reactive. A magnetic resonance imaging (MRI) scan showed bilateral putaminal regions with altered signal, hypointensities in T1-weighted images, hyperintensities on T2-weighted images and hyperintense on Fluid Attenuation Inversion Recovery (FLAIR) images suggestive of cytotoxic edema due to tissue hypoxia [Fig. 3 and 4].

Bottom Line: Magnetic resonance imaging (MRI) scan showed bilateral putaminal regions with altered signal, hypointensities in T1-weighted images, hyperintensities on T2-weighted, images and hyperintense on Fluid Attenuation Inversion Recovery (FLAIR) images suggestive of cytotoxic edema due to tissue hypoxia.Her vision improved to 20/200 in both eyes with treatment after two months.This is the first case report of such nature in the literature to the best of our knowledge.

View Article: PubMed Central - PubMed

Affiliation: Department of Ophthalmology, J. J. M. Medical College, Davangere, Karnataka, India.

ABSTRACT
A 35-year-old female was referred to our hospital with bilateral loss of vision of two days duration. She gave history of consumption of about 150 ml of neem oil five days back.Examination revealed no perception of light in both eyes. Both pupils were dilated and sluggishly reacting to light. Her fundus examination showed bilateral hyperemic, edematous discs and also edema extending along the superior and inferior temporal vascular arcade. Magnetic resonance imaging (MRI) scan showed bilateral putaminal regions with altered signal, hypointensities in T1-weighted images, hyperintensities on T2-weighted, images and hyperintense on Fluid Attenuation Inversion Recovery (FLAIR) images suggestive of cytotoxic edema due to tissue hypoxia. Her vision improved to 20/200 in both eyes with treatment after two months. This is the first case report of such nature in the literature to the best of our knowledge.

Show MeSH
Related in: MedlinePlus