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Effect of left ventricular assist device implantation and heart transplantation on habitual physical activity and quality of life.

Jakovljevic DG, McDiarmid A, Hallsworth K, Seferovic PM, Ninkovic VM, Parry G, Schueler S, Trenell MI, MacGowan GA - Am. J. Cardiol. (2014)

Bottom Line: This was associated with reduced energy expenditure and increased sedentary time (p <0.01).At any time point, HT demonstrated higher activity level than LVAD implantation (p <0.05), and this was associated with better QoL.In conclusion, patients in LVAD and HT patients demonstrate improved physical activity and QoL within the first 3 months after surgery, but physical activity and QoL remain unchanged afterward and well below that of healthy subjects.

View Article: PubMed Central - PubMed

Affiliation: Institute of Cellular Medicine, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom. Electronic address: d.jakovljevic@ncl.ac.uk.

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Related in: MedlinePlus

Longitudinal changes in the daily number of steps (A), physical activity duration (B), active energy expenditure (C), and QoL (D). Healthy data is a single reference data point and not a longitudinal series of data. ∗p <0.05, HT versus LVAD; †p <0.05, HF versus LVAD; ‡p <0.05, HF versus HT.
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fig1: Longitudinal changes in the daily number of steps (A), physical activity duration (B), active energy expenditure (C), and QoL (D). Healthy data is a single reference data point and not a longitudinal series of data. ∗p <0.05, HT versus LVAD; †p <0.05, HF versus LVAD; ‡p <0.05, HF versus HT.

Mentions: During the follow-up period there were no significant changes in body mass during 12 months after LVAD implantation or HT. The body mass was also not changed in patients with HF. Total daily energy expenditure increased significantly from baseline to 3 months in LVAD patients (p <0.05) but remained unchanged from 3 to 12 months after the surgery. In contrast, HT patients demonstrated significantly higher total energy expenditure at 12 months (Table 3). Daily number of steps significantly increased by 60% and 52% from baseline to 3 months in LVAD and HT patients, respectively. It remained, however, unchanged from 3 to 12 months and significantly lower than that of healthy subjects (Figure 1). This was further associated with significant increase in physical activity duration and active energy expenditure (Figure 1). MLHF scores decreased over time from baseline in both LVAD and HT patients indicating an improvement in QoL (Table 3, Figure 1). In contrast with LVAD and HT patients, those with HF had decreased daily number of steps, activity duration, and active energy expenditure at 12 months from baseline and increased MLHF scores (Figure 1).


Effect of left ventricular assist device implantation and heart transplantation on habitual physical activity and quality of life.

Jakovljevic DG, McDiarmid A, Hallsworth K, Seferovic PM, Ninkovic VM, Parry G, Schueler S, Trenell MI, MacGowan GA - Am. J. Cardiol. (2014)

Longitudinal changes in the daily number of steps (A), physical activity duration (B), active energy expenditure (C), and QoL (D). Healthy data is a single reference data point and not a longitudinal series of data. ∗p <0.05, HT versus LVAD; †p <0.05, HF versus LVAD; ‡p <0.05, HF versus HT.
© Copyright Policy - CC BY-NC-ND
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4061472&req=5

fig1: Longitudinal changes in the daily number of steps (A), physical activity duration (B), active energy expenditure (C), and QoL (D). Healthy data is a single reference data point and not a longitudinal series of data. ∗p <0.05, HT versus LVAD; †p <0.05, HF versus LVAD; ‡p <0.05, HF versus HT.
Mentions: During the follow-up period there were no significant changes in body mass during 12 months after LVAD implantation or HT. The body mass was also not changed in patients with HF. Total daily energy expenditure increased significantly from baseline to 3 months in LVAD patients (p <0.05) but remained unchanged from 3 to 12 months after the surgery. In contrast, HT patients demonstrated significantly higher total energy expenditure at 12 months (Table 3). Daily number of steps significantly increased by 60% and 52% from baseline to 3 months in LVAD and HT patients, respectively. It remained, however, unchanged from 3 to 12 months and significantly lower than that of healthy subjects (Figure 1). This was further associated with significant increase in physical activity duration and active energy expenditure (Figure 1). MLHF scores decreased over time from baseline in both LVAD and HT patients indicating an improvement in QoL (Table 3, Figure 1). In contrast with LVAD and HT patients, those with HF had decreased daily number of steps, activity duration, and active energy expenditure at 12 months from baseline and increased MLHF scores (Figure 1).

Bottom Line: This was associated with reduced energy expenditure and increased sedentary time (p <0.01).At any time point, HT demonstrated higher activity level than LVAD implantation (p <0.05), and this was associated with better QoL.In conclusion, patients in LVAD and HT patients demonstrate improved physical activity and QoL within the first 3 months after surgery, but physical activity and QoL remain unchanged afterward and well below that of healthy subjects.

View Article: PubMed Central - PubMed

Affiliation: Institute of Cellular Medicine, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom. Electronic address: d.jakovljevic@ncl.ac.uk.

Show MeSH
Related in: MedlinePlus