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Analysis of laboratory testing results collected in an enhanced chlamydia surveillance system in Australia, 2008-2010.

Dimech W, Lim MS, Van Gemert C, Guy R, Boyle D, Donovan B, Hellard M, ACCESS collaborati - BMC Infect. Dis. (2014)

Bottom Line: Urethral swabs gave the highest positivity rate for all anatomical sites in both female (7.7%) and male patients (14%), followed by urine (7.6% and 9.4%, respectively) and eye (6.3% and 7.9%, respectively).The findings from these data highlight much lower levels of testing in young people aged 20 years or less; in particular female patients aged less than 16 years, despite being the group with the highest positivity rate.Strategies are needed to increase the uptake of testing in this high-risk group.

View Article: PubMed Central - HTML - PubMed

Affiliation: NRL, 4th Floor Healy Building, 41 Victoria Parade, Fitzroy 3065, Australia. wayne@nrl.gov.au.

ABSTRACT

Background: Chlamydial infection is the most common notifiable disease in Australia, Europe and the US. Australian notifications of chlamydia rose four-fold from 20,274 cases in 2002 to 80,846 cases in 2011; the majority of cases were among young people aged less than 29 years. Along with test positivity rates, an understanding of the number of tests performed and the demographics of individuals being tested are key epidemiological indicators. The ACCESS Laboratory Network was established in 2008 to address this issue.

Methods: The ACCESS Laboratory Network collected chlamydia testing data from 15 laboratories around Australia over a three-year period using data extraction software. All chlamydia testing data from participating laboratories were extracted from the laboratory information system; patient identifiers converted to a unique, non-reversible code and de-identified data sent to a single database. Analysis of data by anatomical site included all specimens, but in age and sex specific analysis, only one testing episode was counted.

Results: From 2008 to 2010 a total of 628,295 chlamydia tests were referred to the 15 laboratories. Of the 592,626 individual episodes presenting for testing, 70% were from female and 30% from male patients. In female patients, chlamydia positivity rate was 6.4% overall; the highest rate in 14 year olds (14.3%). In male patients, the chlamydia positivity rate was 9.4% overall; the highest in 19 year olds (16.5%). The most common sample type was urine (57%). In 3.2% of testing episodes, multiple anatomical sites were sampled. Urethral swabs gave the highest positivity rate for all anatomical sites in both female (7.7%) and male patients (14%), followed by urine (7.6% and 9.4%, respectively) and eye (6.3% and 7.9%, respectively).

Conclusions: The ACCESS Laboratory Network data are unique in both number and scope and are representative of chlamydia testing in both general practice and high-risk clinics. The findings from these data highlight much lower levels of testing in young people aged 20 years or less; in particular female patients aged less than 16 years, despite being the group with the highest positivity rate. Strategies are needed to increase the uptake of testing in this high-risk group.

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Chlamydia testing numbers and positivity rates by age and sex, 2008–2010.
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Figure 1: Chlamydia testing numbers and positivity rates by age and sex, 2008–2010.

Mentions: Of the 592,626 testing episodes, 415,069 (70%) tests were from female and 177,557 (30%) from male patients; 417,570 tests (70%) were from individuals aged 16–29 years (Table 1). The highest number of tests was among men and women aged between 20 and 29 (Figure 1). In female patients, 55.4% of samples were urine specimens and 29.3% were cervical (swabs) (Figure 2). The majority (79.6%) of samples collected from male patients were urine specimens (Figure 3).


Analysis of laboratory testing results collected in an enhanced chlamydia surveillance system in Australia, 2008-2010.

Dimech W, Lim MS, Van Gemert C, Guy R, Boyle D, Donovan B, Hellard M, ACCESS collaborati - BMC Infect. Dis. (2014)

Chlamydia testing numbers and positivity rates by age and sex, 2008–2010.
© Copyright Policy - open-access
Related In: Results  -  Collection

License 1 - License 2
Show All Figures
getmorefigures.php?uid=PMC4061452&req=5

Figure 1: Chlamydia testing numbers and positivity rates by age and sex, 2008–2010.
Mentions: Of the 592,626 testing episodes, 415,069 (70%) tests were from female and 177,557 (30%) from male patients; 417,570 tests (70%) were from individuals aged 16–29 years (Table 1). The highest number of tests was among men and women aged between 20 and 29 (Figure 1). In female patients, 55.4% of samples were urine specimens and 29.3% were cervical (swabs) (Figure 2). The majority (79.6%) of samples collected from male patients were urine specimens (Figure 3).

Bottom Line: Urethral swabs gave the highest positivity rate for all anatomical sites in both female (7.7%) and male patients (14%), followed by urine (7.6% and 9.4%, respectively) and eye (6.3% and 7.9%, respectively).The findings from these data highlight much lower levels of testing in young people aged 20 years or less; in particular female patients aged less than 16 years, despite being the group with the highest positivity rate.Strategies are needed to increase the uptake of testing in this high-risk group.

View Article: PubMed Central - HTML - PubMed

Affiliation: NRL, 4th Floor Healy Building, 41 Victoria Parade, Fitzroy 3065, Australia. wayne@nrl.gov.au.

ABSTRACT

Background: Chlamydial infection is the most common notifiable disease in Australia, Europe and the US. Australian notifications of chlamydia rose four-fold from 20,274 cases in 2002 to 80,846 cases in 2011; the majority of cases were among young people aged less than 29 years. Along with test positivity rates, an understanding of the number of tests performed and the demographics of individuals being tested are key epidemiological indicators. The ACCESS Laboratory Network was established in 2008 to address this issue.

Methods: The ACCESS Laboratory Network collected chlamydia testing data from 15 laboratories around Australia over a three-year period using data extraction software. All chlamydia testing data from participating laboratories were extracted from the laboratory information system; patient identifiers converted to a unique, non-reversible code and de-identified data sent to a single database. Analysis of data by anatomical site included all specimens, but in age and sex specific analysis, only one testing episode was counted.

Results: From 2008 to 2010 a total of 628,295 chlamydia tests were referred to the 15 laboratories. Of the 592,626 individual episodes presenting for testing, 70% were from female and 30% from male patients. In female patients, chlamydia positivity rate was 6.4% overall; the highest rate in 14 year olds (14.3%). In male patients, the chlamydia positivity rate was 9.4% overall; the highest in 19 year olds (16.5%). The most common sample type was urine (57%). In 3.2% of testing episodes, multiple anatomical sites were sampled. Urethral swabs gave the highest positivity rate for all anatomical sites in both female (7.7%) and male patients (14%), followed by urine (7.6% and 9.4%, respectively) and eye (6.3% and 7.9%, respectively).

Conclusions: The ACCESS Laboratory Network data are unique in both number and scope and are representative of chlamydia testing in both general practice and high-risk clinics. The findings from these data highlight much lower levels of testing in young people aged 20 years or less; in particular female patients aged less than 16 years, despite being the group with the highest positivity rate. Strategies are needed to increase the uptake of testing in this high-risk group.

Show MeSH
Related in: MedlinePlus