Limits...
Comparison of alveolar ridge preservation methods using three-dimensional micro-computed tomographic analysis and two-dimensional histometric evaluation.

Park YS, Kim S, Oh SH, Park HJ, Lee S, Kim TI, Lee YK, Heo MS - Imaging Sci Dent (2014)

Bottom Line: However, there was no significant association between the data from histometry and micro-CT analysis.These results suggest that alveolar ridge preservation without primary wound closure enhanced new bone formation more effectively than that with primary wound closure.Further investigation is needed with respect to the comparison of histometry and micro-CT analysis.

View Article: PubMed Central - PubMed

Affiliation: Department of Oral Anatomy, Seoul National University School of Dentistry, Seoul, Korea.

ABSTRACT

Purpose: This study evaluated the efficacy of alveolar ridge preservation methods with and without primary wound closure and the relationship between histometric and micro-computed tomographic (CT) data.

Materials and methods: Porcine hydroxyapatite with polytetrafluoroethylene membrane was implanted into a canine extraction socket. The density of the total mineralized tissue, remaining hydroxyapatite, and new bone was analyzed by histometry and micro-CT. The statistical association between these methods was evaluated.

Results: Histometry and micro-CT showed that the group which underwent alveolar preservation without primary wound closure had significantly higher new bone density than the group with primary wound closure (P<0.05). However, there was no significant association between the data from histometry and micro-CT analysis.

Conclusion: These results suggest that alveolar ridge preservation without primary wound closure enhanced new bone formation more effectively than that with primary wound closure. Further investigation is needed with respect to the comparison of histometry and micro-CT analysis.

No MeSH data available.


Related in: MedlinePlus

Microphotograph shows the histologic specimen for mineral tissue measurement (H&E stain, 12.5×).
© Copyright Policy - open-access
Related In: Results  -  Collection

License
getmorefigures.php?uid=PMC4061298&req=5

Figure 2: Microphotograph shows the histologic specimen for mineral tissue measurement (H&E stain, 12.5×).

Mentions: For making histologic specimens, the mandibular blocks were dehydrated in 70-100% ethanol, embedded in methacrylate (Technovit 7200 VCL; Kulzer, Wehrheim, Germany), and sectioned in the mesio-distal plane by using a diamond saw (Exakt, Apparatebau, Norderstedt, Germany). From all the block sections, the central four sections were reduced to a final thickness of 30 µm and stained by hematoxylin-eosin (Fig. 2). The specimens were histologically analyzed under an optical microscope (Leica DM 2500, Leica Microsystems, Wetzlar, Germany).


Comparison of alveolar ridge preservation methods using three-dimensional micro-computed tomographic analysis and two-dimensional histometric evaluation.

Park YS, Kim S, Oh SH, Park HJ, Lee S, Kim TI, Lee YK, Heo MS - Imaging Sci Dent (2014)

Microphotograph shows the histologic specimen for mineral tissue measurement (H&E stain, 12.5×).
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4061298&req=5

Figure 2: Microphotograph shows the histologic specimen for mineral tissue measurement (H&E stain, 12.5×).
Mentions: For making histologic specimens, the mandibular blocks were dehydrated in 70-100% ethanol, embedded in methacrylate (Technovit 7200 VCL; Kulzer, Wehrheim, Germany), and sectioned in the mesio-distal plane by using a diamond saw (Exakt, Apparatebau, Norderstedt, Germany). From all the block sections, the central four sections were reduced to a final thickness of 30 µm and stained by hematoxylin-eosin (Fig. 2). The specimens were histologically analyzed under an optical microscope (Leica DM 2500, Leica Microsystems, Wetzlar, Germany).

Bottom Line: However, there was no significant association between the data from histometry and micro-CT analysis.These results suggest that alveolar ridge preservation without primary wound closure enhanced new bone formation more effectively than that with primary wound closure.Further investigation is needed with respect to the comparison of histometry and micro-CT analysis.

View Article: PubMed Central - PubMed

Affiliation: Department of Oral Anatomy, Seoul National University School of Dentistry, Seoul, Korea.

ABSTRACT

Purpose: This study evaluated the efficacy of alveolar ridge preservation methods with and without primary wound closure and the relationship between histometric and micro-computed tomographic (CT) data.

Materials and methods: Porcine hydroxyapatite with polytetrafluoroethylene membrane was implanted into a canine extraction socket. The density of the total mineralized tissue, remaining hydroxyapatite, and new bone was analyzed by histometry and micro-CT. The statistical association between these methods was evaluated.

Results: Histometry and micro-CT showed that the group which underwent alveolar preservation without primary wound closure had significantly higher new bone density than the group with primary wound closure (P<0.05). However, there was no significant association between the data from histometry and micro-CT analysis.

Conclusion: These results suggest that alveolar ridge preservation without primary wound closure enhanced new bone formation more effectively than that with primary wound closure. Further investigation is needed with respect to the comparison of histometry and micro-CT analysis.

No MeSH data available.


Related in: MedlinePlus