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Quantification of myocardial viability in diffuse and contiguous infarction using 3D inversion recovery MRI: Validation against microscopy

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Correlation between myocardial infarction measured on 3D MRI in beating hearts and microscopy (y = 1.1 × -3.5).
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Figure 1: Correlation between myocardial infarction measured on 3D MRI in beating hearts and microscopy (y = 1.1 × -3.5).

Mentions: There was no significant difference in infarction size between delayed contrast enhanced 3D and 2D MRI in both beating and non-beating hearts (Table 1). Furthermore, theses sequences demonstrated the gradients in infarction size as a function of insult severity. In beating hearts close correlations and agreements were found between infarction size measured on 3D and 2D MRI (r = 0.81-0.95 for all groups, bias: group I = 0.033 ± 1.2%, group II = 0.13 ± 1.2%, group III = -0.17 ± 1.8%). Acute large infarction was overestimated on 3D and 2D MRI in beating hearts compared with microscopy due to the inclusion of edematous border zone. Figure 1 demonstrates a close correlation between 3D MRI in beating hearts and microscopy of combined large and diffuse infarction (group III), but 3D MRI underestimated true myocardial infarction size (bias: -2.2 ± 1.6%) due to the inherent limited spatial resolution and the small islands of necrosis in the area at risk.


Quantification of myocardial viability in diffuse and contiguous infarction using 3D inversion recovery MRI: Validation against microscopy
Correlation between myocardial infarction measured on 3D MRI in beating hearts and microscopy (y = 1.1 × -3.5).
© Copyright Policy - open-access
Related In: Results  -  Collection

License 1 - License 2
Show All Figures
getmorefigures.php?uid=PMC4045604&req=5

Figure 1: Correlation between myocardial infarction measured on 3D MRI in beating hearts and microscopy (y = 1.1 × -3.5).
Mentions: There was no significant difference in infarction size between delayed contrast enhanced 3D and 2D MRI in both beating and non-beating hearts (Table 1). Furthermore, theses sequences demonstrated the gradients in infarction size as a function of insult severity. In beating hearts close correlations and agreements were found between infarction size measured on 3D and 2D MRI (r = 0.81-0.95 for all groups, bias: group I = 0.033 ± 1.2%, group II = 0.13 ± 1.2%, group III = -0.17 ± 1.8%). Acute large infarction was overestimated on 3D and 2D MRI in beating hearts compared with microscopy due to the inclusion of edematous border zone. Figure 1 demonstrates a close correlation between 3D MRI in beating hearts and microscopy of combined large and diffuse infarction (group III), but 3D MRI underestimated true myocardial infarction size (bias: -2.2 ± 1.6%) due to the inherent limited spatial resolution and the small islands of necrosis in the area at risk.

View Article: PubMed Central - HTML

No MeSH data available.


Related in: MedlinePlus