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Mentions: There was no significant difference in infarction size between delayed contrast enhanced 3D and 2D MRI in both beating and non-beating hearts (Table 1). Furthermore, theses sequences demonstrated the gradients in infarction size as a function of insult severity. In beating hearts close correlations and agreements were found between infarction size measured on 3D and 2D MRI (r = 0.81-0.95 for all groups, bias: group I = 0.033 ± 1.2%, group II = 0.13 ± 1.2%, group III = -0.17 ± 1.8%). Acute large infarction was overestimated on 3D and 2D MRI in beating hearts compared with microscopy due to the inclusion of edematous border zone. Figure 1 demonstrates a close correlation between 3D MRI in beating hearts and microscopy of combined large and diffuse infarction (group III), but 3D MRI underestimated true myocardial infarction size (bias: -2.2 ± 1.6%) due to the inherent limited spatial resolution and the small islands of necrosis in the area at risk.
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