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Predictability of the individual clinical outcome of extracorporeal shock wave therapy for cellulite.

Schlaudraff KU, Kiessling MC, Császár NB, Schmitz C - Clin Cosmet Investig Dermatol (2014)

Bottom Line: Compared with baseline, no patient's condition worsened, the treatment was well tolerated, and no unwanted side effects were observed.No statistically significant (ie, P<0.05) correlation was found between individual values for δ-1 and δ-2 and cellulite grade at baseline, BMI, weight, height, or age.The individual clinical outcome cannot be predicted by the patient's individual cellulite grade at baseline, BMI, weight, height, or age.

View Article: PubMed Central - PubMed

Affiliation: Concept Clinic, Geneva, Switzerland.

ABSTRACT

Background: Extracorporeal shock wave therapy has been successfully introduced for the treatment of cellulite in recent years. However, it is still unknown whether the individual clinical outcome of cellulite treatment with extracorporeal shock wave therapy can be predicted by the patient's individual cellulite grade at baseline, individual patient age, body mass index (BMI), weight, and/or height.

Methods: Fourteen Caucasian females with cellulite were enrolled in a prospective, single-center, randomized, open-label Phase II study. The mean (± standard error of the mean) cellulite grade at baseline was 2.5±0.09 and mean BMI was 22.8±1.17. All patients were treated with radial extracorporeal shock waves using the Swiss DolorClast(®) device (Electro Medical Systems, S.A., Nyon, Switzerland). Patients were treated unilaterally with 2 weekly treatments for 4 weeks on a randomly selected side (left or right), totaling eight treatments on the selected side. Treatment was performed at 3.5-4.0 bar, with 15,000 impulses per session applied at 15 Hz. Impulses were homogeneously distributed over the posterior thigh and buttock area (resulting in 7,500 impulses per area). Treatment success was evaluated after the last treatment and 4 weeks later by clinical examination, photographic documentation, contact thermography, and patient satisfaction questionnaires.

Results: The mean cellulite grade improved from 2.5±0.09 at baseline to 1.57±0.18 after the last treatment (ie, mean δ-1 was 0.93 cellulite grades) and 1.68±0.16 at follow-up (ie, mean δ-2 was 0.82 cellulite grades). Compared with baseline, no patient's condition worsened, the treatment was well tolerated, and no unwanted side effects were observed. No statistically significant (ie, P<0.05) correlation was found between individual values for δ-1 and δ-2 and cellulite grade at baseline, BMI, weight, height, or age.

Conclusion: Radial shock wave therapy is a safe and effective treatment option for cellulite. The individual clinical outcome cannot be predicted by the patient's individual cellulite grade at baseline, BMI, weight, height, or age.

No MeSH data available.


Related in: MedlinePlus

Clinical outcome of radial extracorporeal shock wave therapy for cellulite as a function of the patients’ pain during the treatment (A and B), the patients’ feeling of comfort during treatment (C and D), and the patients’ satisfaction with treatment (E and F) (calculated as individual difference in cellulite grades either between baseline and after the last treatment [δ-1] or between baseline and at follow-up [δ-2], respectively; the higher δ-1 and δ-2, the better the treatment success).Notes: Each dot represents an individual patient; overlapping data are indicated. Pain was assessed using a visual analog scale ranging from 0 (no pain) to 10 (maximum pain). The feeling of comfort was assessed using a scale ranging from 0 (maximum discomfort) to 10 (maximum comfort), and patients’ satisfaction using a scale ranging from 0 (maximum dissatisfaction) to 10 (maximum satisfaction). The Spearman’s nonparametric rank correlation coefficients (r) and the corresponding P-values are provided in red on top of each panel.
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f5-ccid-7-171: Clinical outcome of radial extracorporeal shock wave therapy for cellulite as a function of the patients’ pain during the treatment (A and B), the patients’ feeling of comfort during treatment (C and D), and the patients’ satisfaction with treatment (E and F) (calculated as individual difference in cellulite grades either between baseline and after the last treatment [δ-1] or between baseline and at follow-up [δ-2], respectively; the higher δ-1 and δ-2, the better the treatment success).Notes: Each dot represents an individual patient; overlapping data are indicated. Pain was assessed using a visual analog scale ranging from 0 (no pain) to 10 (maximum pain). The feeling of comfort was assessed using a scale ranging from 0 (maximum discomfort) to 10 (maximum comfort), and patients’ satisfaction using a scale ranging from 0 (maximum dissatisfaction) to 10 (maximum satisfaction). The Spearman’s nonparametric rank correlation coefficients (r) and the corresponding P-values are provided in red on top of each panel.

Mentions: No statistically significant (ie, P<0.05/8) correlation was found between δ-1 or δ-2 and cellulite grade at baseline, BMI, weight, height, age, pain during treatment, feeling of comfort during treatment, or satisfaction at the end of treatment (or at the end of the follow-up period, Figures 4 and 5).


Predictability of the individual clinical outcome of extracorporeal shock wave therapy for cellulite.

Schlaudraff KU, Kiessling MC, Császár NB, Schmitz C - Clin Cosmet Investig Dermatol (2014)

Clinical outcome of radial extracorporeal shock wave therapy for cellulite as a function of the patients’ pain during the treatment (A and B), the patients’ feeling of comfort during treatment (C and D), and the patients’ satisfaction with treatment (E and F) (calculated as individual difference in cellulite grades either between baseline and after the last treatment [δ-1] or between baseline and at follow-up [δ-2], respectively; the higher δ-1 and δ-2, the better the treatment success).Notes: Each dot represents an individual patient; overlapping data are indicated. Pain was assessed using a visual analog scale ranging from 0 (no pain) to 10 (maximum pain). The feeling of comfort was assessed using a scale ranging from 0 (maximum discomfort) to 10 (maximum comfort), and patients’ satisfaction using a scale ranging from 0 (maximum dissatisfaction) to 10 (maximum satisfaction). The Spearman’s nonparametric rank correlation coefficients (r) and the corresponding P-values are provided in red on top of each panel.
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4043818&req=5

f5-ccid-7-171: Clinical outcome of radial extracorporeal shock wave therapy for cellulite as a function of the patients’ pain during the treatment (A and B), the patients’ feeling of comfort during treatment (C and D), and the patients’ satisfaction with treatment (E and F) (calculated as individual difference in cellulite grades either between baseline and after the last treatment [δ-1] or between baseline and at follow-up [δ-2], respectively; the higher δ-1 and δ-2, the better the treatment success).Notes: Each dot represents an individual patient; overlapping data are indicated. Pain was assessed using a visual analog scale ranging from 0 (no pain) to 10 (maximum pain). The feeling of comfort was assessed using a scale ranging from 0 (maximum discomfort) to 10 (maximum comfort), and patients’ satisfaction using a scale ranging from 0 (maximum dissatisfaction) to 10 (maximum satisfaction). The Spearman’s nonparametric rank correlation coefficients (r) and the corresponding P-values are provided in red on top of each panel.
Mentions: No statistically significant (ie, P<0.05/8) correlation was found between δ-1 or δ-2 and cellulite grade at baseline, BMI, weight, height, age, pain during treatment, feeling of comfort during treatment, or satisfaction at the end of treatment (or at the end of the follow-up period, Figures 4 and 5).

Bottom Line: Compared with baseline, no patient's condition worsened, the treatment was well tolerated, and no unwanted side effects were observed.No statistically significant (ie, P<0.05) correlation was found between individual values for δ-1 and δ-2 and cellulite grade at baseline, BMI, weight, height, or age.The individual clinical outcome cannot be predicted by the patient's individual cellulite grade at baseline, BMI, weight, height, or age.

View Article: PubMed Central - PubMed

Affiliation: Concept Clinic, Geneva, Switzerland.

ABSTRACT

Background: Extracorporeal shock wave therapy has been successfully introduced for the treatment of cellulite in recent years. However, it is still unknown whether the individual clinical outcome of cellulite treatment with extracorporeal shock wave therapy can be predicted by the patient's individual cellulite grade at baseline, individual patient age, body mass index (BMI), weight, and/or height.

Methods: Fourteen Caucasian females with cellulite were enrolled in a prospective, single-center, randomized, open-label Phase II study. The mean (± standard error of the mean) cellulite grade at baseline was 2.5±0.09 and mean BMI was 22.8±1.17. All patients were treated with radial extracorporeal shock waves using the Swiss DolorClast(®) device (Electro Medical Systems, S.A., Nyon, Switzerland). Patients were treated unilaterally with 2 weekly treatments for 4 weeks on a randomly selected side (left or right), totaling eight treatments on the selected side. Treatment was performed at 3.5-4.0 bar, with 15,000 impulses per session applied at 15 Hz. Impulses were homogeneously distributed over the posterior thigh and buttock area (resulting in 7,500 impulses per area). Treatment success was evaluated after the last treatment and 4 weeks later by clinical examination, photographic documentation, contact thermography, and patient satisfaction questionnaires.

Results: The mean cellulite grade improved from 2.5±0.09 at baseline to 1.57±0.18 after the last treatment (ie, mean δ-1 was 0.93 cellulite grades) and 1.68±0.16 at follow-up (ie, mean δ-2 was 0.82 cellulite grades). Compared with baseline, no patient's condition worsened, the treatment was well tolerated, and no unwanted side effects were observed. No statistically significant (ie, P<0.05) correlation was found between individual values for δ-1 and δ-2 and cellulite grade at baseline, BMI, weight, height, or age.

Conclusion: Radial shock wave therapy is a safe and effective treatment option for cellulite. The individual clinical outcome cannot be predicted by the patient's individual cellulite grade at baseline, BMI, weight, height, or age.

No MeSH data available.


Related in: MedlinePlus